Multivariate Cox-proportional hazard analysis of 1-year events in the entire cohort
| Events . | With beta-blocker (N = 10 251) . | Without beta-blocker (N = 1949) . | Hazard ratioa (95% CI) . | P-value . | ||
|---|---|---|---|---|---|---|
| . | No. of patients with events . | Rate per 100 patient-yearb . | No. of patients with events . | Rate per 100 patient-yearb . | . | . |
| MACE | 919 | 9.7 | 247 | 14.3 | 0.84 (0.72–0.97) | 0.022 |
| Cardiac death | 248 | 2.5 | 99 | 5.5 | 0.74 (0.57–0.96) | 0.022 |
| All-cause death | 384 | 3.9 | 134 | 7.4 | 0.81 (0.65–1.00) | 0.053 |
| MI | 190 | 2.0 | 35 | 2.0 | 1.10 (0.75–1.63) | 0.620 |
| Revascularization | 448 | 4.7 | 84 | 4.8 | 0.99 (0.77–1.28) | 0.958 |
| Heart failurec | 250 | 2.6 | 76 | 4.3 | 0.82 (0.62–1.08) | 0.157 |
| Stroke | 110 | 1.1 | 16 | 0.9 | 1.37 (0.79–2.36) | 0.259 |
| MACCE | 1,009 | 10.7 | 259 | 15.1 | 0.87 (0.75–1.01) | 0.067 |
| Events . | With beta-blocker (N = 10 251) . | Without beta-blocker (N = 1949) . | Hazard ratioa (95% CI) . | P-value . | ||
|---|---|---|---|---|---|---|
| . | No. of patients with events . | Rate per 100 patient-yearb . | No. of patients with events . | Rate per 100 patient-yearb . | . | . |
| MACE | 919 | 9.7 | 247 | 14.3 | 0.84 (0.72–0.97) | 0.022 |
| Cardiac death | 248 | 2.5 | 99 | 5.5 | 0.74 (0.57–0.96) | 0.022 |
| All-cause death | 384 | 3.9 | 134 | 7.4 | 0.81 (0.65–1.00) | 0.053 |
| MI | 190 | 2.0 | 35 | 2.0 | 1.10 (0.75–1.63) | 0.620 |
| Revascularization | 448 | 4.7 | 84 | 4.8 | 0.99 (0.77–1.28) | 0.958 |
| Heart failurec | 250 | 2.6 | 76 | 4.3 | 0.82 (0.62–1.08) | 0.157 |
| Stroke | 110 | 1.1 | 16 | 0.9 | 1.37 (0.79–2.36) | 0.259 |
| MACCE | 1,009 | 10.7 | 259 | 15.1 | 0.87 (0.75–1.01) | 0.067 |
CI, confidence interval; MACCE, major adverse cardiocerebral event; MACE, major adverse cardiac event; MI, myocardial infarction.
Adjusted for age, sex, body mass index, hypertension, diabetes mellitus, prior angina, prior MI, prior heart failure, current smoker, Killip class, estimated glomerular filtration rate, left ventricular ejection fraction, type of myocardial infarction, coronary reperfusion, and medications (aspirin, P2Y12 inhibitors, inhibitors of renin-angiotensin system, and statins) at discharge.
Unadjusted event rate.
Re-hospitalization due to heart failure.
Multivariate Cox-proportional hazard analysis of 1-year events in the entire cohort
| Events . | With beta-blocker (N = 10 251) . | Without beta-blocker (N = 1949) . | Hazard ratioa (95% CI) . | P-value . | ||
|---|---|---|---|---|---|---|
| . | No. of patients with events . | Rate per 100 patient-yearb . | No. of patients with events . | Rate per 100 patient-yearb . | . | . |
| MACE | 919 | 9.7 | 247 | 14.3 | 0.84 (0.72–0.97) | 0.022 |
| Cardiac death | 248 | 2.5 | 99 | 5.5 | 0.74 (0.57–0.96) | 0.022 |
| All-cause death | 384 | 3.9 | 134 | 7.4 | 0.81 (0.65–1.00) | 0.053 |
| MI | 190 | 2.0 | 35 | 2.0 | 1.10 (0.75–1.63) | 0.620 |
| Revascularization | 448 | 4.7 | 84 | 4.8 | 0.99 (0.77–1.28) | 0.958 |
| Heart failurec | 250 | 2.6 | 76 | 4.3 | 0.82 (0.62–1.08) | 0.157 |
| Stroke | 110 | 1.1 | 16 | 0.9 | 1.37 (0.79–2.36) | 0.259 |
| MACCE | 1,009 | 10.7 | 259 | 15.1 | 0.87 (0.75–1.01) | 0.067 |
| Events . | With beta-blocker (N = 10 251) . | Without beta-blocker (N = 1949) . | Hazard ratioa (95% CI) . | P-value . | ||
|---|---|---|---|---|---|---|
| . | No. of patients with events . | Rate per 100 patient-yearb . | No. of patients with events . | Rate per 100 patient-yearb . | . | . |
| MACE | 919 | 9.7 | 247 | 14.3 | 0.84 (0.72–0.97) | 0.022 |
| Cardiac death | 248 | 2.5 | 99 | 5.5 | 0.74 (0.57–0.96) | 0.022 |
| All-cause death | 384 | 3.9 | 134 | 7.4 | 0.81 (0.65–1.00) | 0.053 |
| MI | 190 | 2.0 | 35 | 2.0 | 1.10 (0.75–1.63) | 0.620 |
| Revascularization | 448 | 4.7 | 84 | 4.8 | 0.99 (0.77–1.28) | 0.958 |
| Heart failurec | 250 | 2.6 | 76 | 4.3 | 0.82 (0.62–1.08) | 0.157 |
| Stroke | 110 | 1.1 | 16 | 0.9 | 1.37 (0.79–2.36) | 0.259 |
| MACCE | 1,009 | 10.7 | 259 | 15.1 | 0.87 (0.75–1.01) | 0.067 |
CI, confidence interval; MACCE, major adverse cardiocerebral event; MACE, major adverse cardiac event; MI, myocardial infarction.
Adjusted for age, sex, body mass index, hypertension, diabetes mellitus, prior angina, prior MI, prior heart failure, current smoker, Killip class, estimated glomerular filtration rate, left ventricular ejection fraction, type of myocardial infarction, coronary reperfusion, and medications (aspirin, P2Y12 inhibitors, inhibitors of renin-angiotensin system, and statins) at discharge.
Unadjusted event rate.
Re-hospitalization due to heart failure.
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