Risk Associations of Hospital-onset Clostridioides difficile Infection Determined by Unadjusted Bivariate Analysis (N = 8763)
| Characteristic . | OR (95% CI) . | P Value . |
|---|---|---|
| Demographics | ||
| Age ≥65 y | 1.27 (.75–2.14) | .4 |
| Male sex | 1.20 (.71–2.03) | .5 |
| Intensive care unit | 3.31 (1.62–6.77) | .001 |
| Concomitant medications | ||
| Metronidazole | 1.00 (.47–2.1) | 1.0 |
| Proton pump inhibitor | 1.78 (1.05–3.01) | .03 |
| Intervention | ||
| Saccharomyces boulardii and antibiotic | 0.68 (.41–1.1) | .2 |
| Characteristic . | OR (95% CI) . | P Value . |
|---|---|---|
| Demographics | ||
| Age ≥65 y | 1.27 (.75–2.14) | .4 |
| Male sex | 1.20 (.71–2.03) | .5 |
| Intensive care unit | 3.31 (1.62–6.77) | .001 |
| Concomitant medications | ||
| Metronidazole | 1.00 (.47–2.1) | 1.0 |
| Proton pump inhibitor | 1.78 (1.05–3.01) | .03 |
| Intervention | ||
| Saccharomyces boulardii and antibiotic | 0.68 (.41–1.1) | .2 |
Abbreviations: CI, confidence interval; HO-CDI, hospital-onset Clostridioides difficile infection; OR, odds ratio.
Risk Associations of Hospital-onset Clostridioides difficile Infection Determined by Unadjusted Bivariate Analysis (N = 8763)
| Characteristic . | OR (95% CI) . | P Value . |
|---|---|---|
| Demographics | ||
| Age ≥65 y | 1.27 (.75–2.14) | .4 |
| Male sex | 1.20 (.71–2.03) | .5 |
| Intensive care unit | 3.31 (1.62–6.77) | .001 |
| Concomitant medications | ||
| Metronidazole | 1.00 (.47–2.1) | 1.0 |
| Proton pump inhibitor | 1.78 (1.05–3.01) | .03 |
| Intervention | ||
| Saccharomyces boulardii and antibiotic | 0.68 (.41–1.1) | .2 |
| Characteristic . | OR (95% CI) . | P Value . |
|---|---|---|
| Demographics | ||
| Age ≥65 y | 1.27 (.75–2.14) | .4 |
| Male sex | 1.20 (.71–2.03) | .5 |
| Intensive care unit | 3.31 (1.62–6.77) | .001 |
| Concomitant medications | ||
| Metronidazole | 1.00 (.47–2.1) | 1.0 |
| Proton pump inhibitor | 1.78 (1.05–3.01) | .03 |
| Intervention | ||
| Saccharomyces boulardii and antibiotic | 0.68 (.41–1.1) | .2 |
Abbreviations: CI, confidence interval; HO-CDI, hospital-onset Clostridioides difficile infection; OR, odds ratio.
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