Table 2 Open in new tab Comparing...

	Admitted Then Discharged (n = 1,445)	Admitted Then Died (n = 118)	Admitted, Ventilated, Discharged (n = 202)	Admitted, Ventilated, Died (n = 119)	Total (N = 1884)
No. of days to initial ventilation, median (IQR)^a,^b			1.00 (0, 2.00)	1.00 (0, 3.00)
No. of days to discharge/death, median (IQR)^a,^b	4.00 (2.00, 7.00)	5.00 (1.00, 9.00)	20.0 (12.0, 31.8)	11.0 (6.00, 20.0)	5.00 (2.00, 10.0)
Age, median (IQR), years^a,^b	56.0 (41.0, 71.0)	82.5 (73.0, 91.0)	60.5 (51.0, 70.8)	70.0 (63.0, 80.5)	60.0 (44.0, 73.0)
Age, %, years^a
<60	817	56.5	3	2.5	99	49.0	22	18.5	941	49.9
60–74	356	24.6	30	25.4	72	35.6	52	43.7	510	27.1
>74	272	18.8	85	72.0	31	15.3	45	37.8	433	23.0
Race, %^a
White	376	26.0	59	50.0	52	25.7	43	36.1	530	28.1
Black	499	34.5	39	33.1	80	39.6	47	39.5	665	35.3
Latinx/other	569	39.4	20	16.9	70	34.7	29	24.4	688	36.5
Missing data	1	0.1	0	0	0	0	0	0	1	0.1
Sex, %^c
Female	702	48.6	49	41.5	85	42.1	52	43.7	888	47.1
Male	743	51.4	69	58.5	117	57.9	67	56.3	996	52.9
Body mass index, %^a,^d
<18.5	35	2.4	12	10.2	4	2.0	2	1.7	53	2.8
18.5– 24.9	304	21.0	44	37.3	32	15.8	29	24.4	409	21.7
25.0–29.9	379	26.2	23	19.5	48	23.8	30	25.2	480	25.5
30.0–39.9	405	28.0	14	11.9	58	28.7	27	22.7	504	26.8
≥40.0	116	8.0	2	1.7	22	10.9	13	10.9	153	8.1
Missing data	206	14.3	23	19.5	38	18.8	18	15.1	285	15.1
Diabetes^a,^e	374	25.9	28	23.7	72	35.6	46	38.7	520	27.6
Smoking history, %^a
Current smoker	78	5.4	7	5.9	19	9.4	6	5.0	110	5.8
Former smoker	284	19.7	35	29.7	57	28.2	33	27.7	409	21.7
Never smoker	957	66.2	48	40.7	109	54.0	50	42.0	1,164	61.8
Missing data	126	8.7	28	23.7	17	8.4	30	25.2	201	10.7
CCI score, median (IQR)^a	1.00 [0, 2.00]	2.00 [1.00, 3.00]	1.00 [0, 3.00]	1.00 [1.00, 3.00]	1.00 [0, 2.00]
CCI score, %^a
0	658	45.5	14	11.9	74	36.6	27	22.7	773	41.0
1–2	580	40.1	56	47.5	76	37.6	59	49.6	771	40.9
3–4	170	11.8	38	32.2	35	17.3	20	16.8	263	14.0
>5	30	2.1	10	8.5	17	8.4	13	10.9	70	3.7
Missing data	7	0.5	0	0	0	0	0	0	7	0.4
Ever had DNR/DNI order, %^a	175	12.1	112	94.9	35	17.3	105	88.2	427	22.7

Admitted Then Discharged (n = 1,445)

Admitted Then Died (n = 118)

Admitted, Ventilated, Discharged (n = 202)

Admitted, Ventilated, Died (n = 119)

Total (N = 1884)

Patient Characteristic

No.

No. of days to initial ventilation, median (IQR)^a,^b

1.00 (0, 2.00)

1.00 (0, 3.00)

No. of days to discharge/death, median (IQR)^a,^b

4.00 (2.00, 7.00)

5.00 (1.00, 9.00)

20.0 (12.0, 31.8)

11.0 (6.00, 20.0)

5.00 (2.00, 10.0)

Age, median (IQR), years^a,^b

56.0 (41.0, 71.0)

82.5 (73.0, 91.0)

60.5 (51.0, 70.8)

70.0 (63.0, 80.5)

60.0 (44.0, 73.0)

Age, %, years^a

<60

817

56.5

2.5

49.0

18.5

941

49.9

60–74

356

24.6

25.4

35.6

43.7

510

27.1

>74

272

18.8

72.0

15.3

37.8

433

23.0

Race, %^a

White

376

26.0

50.0

25.7

36.1

530

28.1

Black

499

34.5

33.1

39.6

39.5

665

35.3

Latinx/other

569

39.4

16.9

34.7

24.4

688

36.5

Missing data

0.1

Sex, %^c

Female

702

48.6

41.5

42.1

43.7

888

47.1

Male

743

51.4

58.5

117

57.9

56.3

996

52.9

Body mass index, %^a,^d

<18.5

2.4

10.2

2.0

1.7

2.8

18.5– 24.9

304

21.0

37.3

15.8

24.4

409

21.7

25.0–29.9

379

26.2

19.5

23.8

25.2

480

25.5

30.0–39.9

405

28.0

11.9

28.7

22.7

504

26.8

≥40.0

116

8.0

1.7

10.9

153

8.1

Missing data

206

14.3

19.5

18.8

15.1

285

15.1

Diabetes^a,^e

374

25.9

23.7

35.6

38.7

520

27.6

Smoking history, %^a

Current smoker

5.4

5.9

9.4

5.0

110

5.8

Former smoker

284

19.7

29.7

28.2

27.7

409

21.7

Never smoker

957

66.2

40.7

109

54.0

42.0

1,164

61.8

Missing data

126

8.7

23.7

8.4

25.2

201

10.7

CCI score, median (IQR)^a

1.00 [0, 2.00]

2.00 [1.00, 3.00]

1.00 [0, 3.00]

1.00 [1.00, 3.00]

1.00 [0, 2.00]

CCI score, %^a

658

45.5

11.9

36.6

22.7

773

41.0

1–2

580

40.1

47.5

37.6

49.6

771

40.9

3–4

170

11.8

32.2

17.3

16.8

263

14.0

2.1

8.5

8.4

10.9

3.7

Missing data

0.5

0.4

Ever had DNR/DNI order, %^a

175

12.1

112

94.9

17.3

105

88.2

427

22.7

	Admitted Then Discharged (n = 1,445)	Admitted Then Died (n = 118)	Admitted, Ventilated, Discharged (n = 202)	Admitted, Ventilated, Died (n = 119)	Total (N = 1884)
No. of days to initial ventilation, median (IQR)^a,^b			1.00 (0, 2.00)	1.00 (0, 3.00)
No. of days to discharge/death, median (IQR)^a,^b	4.00 (2.00, 7.00)	5.00 (1.00, 9.00)	20.0 (12.0, 31.8)	11.0 (6.00, 20.0)	5.00 (2.00, 10.0)
Age, median (IQR), years^a,^b	56.0 (41.0, 71.0)	82.5 (73.0, 91.0)	60.5 (51.0, 70.8)	70.0 (63.0, 80.5)	60.0 (44.0, 73.0)
Age, %, years^a
<60	817	56.5	3	2.5	99	49.0	22	18.5	941	49.9
60–74	356	24.6	30	25.4	72	35.6	52	43.7	510	27.1
>74	272	18.8	85	72.0	31	15.3	45	37.8	433	23.0
Race, %^a
White	376	26.0	59	50.0	52	25.7	43	36.1	530	28.1
Black	499	34.5	39	33.1	80	39.6	47	39.5	665	35.3
Latinx/other	569	39.4	20	16.9	70	34.7	29	24.4	688	36.5
Missing data	1	0.1	0	0	0	0	0	0	1	0.1
Sex, %^c
Female	702	48.6	49	41.5	85	42.1	52	43.7	888	47.1
Male	743	51.4	69	58.5	117	57.9	67	56.3	996	52.9
Body mass index, %^a,^d
<18.5	35	2.4	12	10.2	4	2.0	2	1.7	53	2.8
18.5– 24.9	304	21.0	44	37.3	32	15.8	29	24.4	409	21.7
25.0–29.9	379	26.2	23	19.5	48	23.8	30	25.2	480	25.5
30.0–39.9	405	28.0	14	11.9	58	28.7	27	22.7	504	26.8
≥40.0	116	8.0	2	1.7	22	10.9	13	10.9	153	8.1
Missing data	206	14.3	23	19.5	38	18.8	18	15.1	285	15.1
Diabetes^a,^e	374	25.9	28	23.7	72	35.6	46	38.7	520	27.6
Smoking history, %^a
Current smoker	78	5.4	7	5.9	19	9.4	6	5.0	110	5.8
Former smoker	284	19.7	35	29.7	57	28.2	33	27.7	409	21.7
Never smoker	957	66.2	48	40.7	109	54.0	50	42.0	1,164	61.8
Missing data	126	8.7	28	23.7	17	8.4	30	25.2	201	10.7
CCI score, median (IQR)^a	1.00 [0, 2.00]	2.00 [1.00, 3.00]	1.00 [0, 3.00]	1.00 [1.00, 3.00]	1.00 [0, 2.00]
CCI score, %^a
0	658	45.5	14	11.9	74	36.6	27	22.7	773	41.0
1–2	580	40.1	56	47.5	76	37.6	59	49.6	771	40.9
3–4	170	11.8	38	32.2	35	17.3	20	16.8	263	14.0
>5	30	2.1	10	8.5	17	8.4	13	10.9	70	3.7
Missing data	7	0.5	0	0	0	0	0	0	7	0.4
Ever had DNR/DNI order, %^a	175	12.1	112	94.9	35	17.3	105	88.2	427	22.7

Table 2

Open in new tab

Comparing Characteristics of Patients With COVID-19 Across Outcome Strata From Within the Johns Hopkins COVID-19 Precision Medicine Analytics Platform Registry, Baltimore, Maryland, April 3, 2020–June 25, 2020

	Admitted Then Discharged (n = 1,445)		Admitted Then Died (n = 118)		Admitted, Ventilated, Discharged (n = 202)		Admitted, Ventilated, Died (n = 119)		Total (N = 1884)
Patient Characteristic	No.	%	No.	%	No.	%	No.	%	No.	%
No. of days to initial ventilation, median (IQR)^a,^b					1.00 (0, 2.00)		1.00 (0, 3.00)
No. of days to discharge/death, median (IQR)^a,^b	4.00 (2.00, 7.00)		5.00 (1.00, 9.00)		20.0 (12.0, 31.8)		11.0 (6.00, 20.0)		5.00 (2.00, 10.0)
Age, median (IQR), years^a,^b	56.0 (41.0, 71.0)		82.5 (73.0, 91.0)		60.5 (51.0, 70.8)		70.0 (63.0, 80.5)		60.0 (44.0, 73.0)
Age, %, years^a
<60	817	56.5	3	2.5	99	49.0	22	18.5	941	49.9
60–74	356	24.6	30	25.4	72	35.6	52	43.7	510	27.1
>74	272	18.8	85	72.0	31	15.3	45	37.8	433	23.0
Race, %^a
White	376	26.0	59	50.0	52	25.7	43	36.1	530	28.1
Black	499	34.5	39	33.1	80	39.6	47	39.5	665	35.3
Latinx/other	569	39.4	20	16.9	70	34.7	29	24.4	688	36.5
Missing data	1	0.1	0	0	0	0	0	0	1	0.1
Sex, %^c
Female	702	48.6	49	41.5	85	42.1	52	43.7	888	47.1
Male	743	51.4	69	58.5	117	57.9	67	56.3	996	52.9
Body mass index, %^a,^d
<18.5	35	2.4	12	10.2	4	2.0	2	1.7	53	2.8
18.5– 24.9	304	21.0	44	37.3	32	15.8	29	24.4	409	21.7
25.0–29.9	379	26.2	23	19.5	48	23.8	30	25.2	480	25.5
30.0–39.9	405	28.0	14	11.9	58	28.7	27	22.7	504	26.8
≥40.0	116	8.0	2	1.7	22	10.9	13	10.9	153	8.1
Missing data	206	14.3	23	19.5	38	18.8	18	15.1	285	15.1
Diabetes^a,^e	374	25.9	28	23.7	72	35.6	46	38.7	520	27.6
Smoking history, %^a
Current smoker	78	5.4	7	5.9	19	9.4	6	5.0	110	5.8
Former smoker	284	19.7	35	29.7	57	28.2	33	27.7	409	21.7
Never smoker	957	66.2	48	40.7	109	54.0	50	42.0	1,164	61.8
Missing data	126	8.7	28	23.7	17	8.4	30	25.2	201	10.7
CCI score, median (IQR)^a	1.00 [0, 2.00]		2.00 [1.00, 3.00]		1.00 [0, 3.00]		1.00 [1.00, 3.00]		1.00 [0, 2.00]
CCI score, %^a
0	658	45.5	14	11.9	74	36.6	27	22.7	773	41.0
1–2	580	40.1	56	47.5	76	37.6	59	49.6	771	40.9
3–4	170	11.8	38	32.2	35	17.3	20	16.8	263	14.0
>5	30	2.1	10	8.5	17	8.4	13	10.9	70	3.7
Missing data	7	0.5	0	0	0	0	0	0	7	0.4
Ever had DNR/DNI order, %^a	175	12.1	112	94.9	35	17.3	105	88.2	427	22.7

	Admitted Then Discharged (n = 1,445)		Admitted Then Died (n = 118)		Admitted, Ventilated, Discharged (n = 202)		Admitted, Ventilated, Died (n = 119)		Total (N = 1884)
Patient Characteristic	No.	%	No.	%	No.	%	No.	%	No.	%
No. of days to initial ventilation, median (IQR)^a,^b					1.00 (0, 2.00)		1.00 (0, 3.00)
No. of days to discharge/death, median (IQR)^a,^b	4.00 (2.00, 7.00)		5.00 (1.00, 9.00)		20.0 (12.0, 31.8)		11.0 (6.00, 20.0)		5.00 (2.00, 10.0)
Age, median (IQR), years^a,^b	56.0 (41.0, 71.0)		82.5 (73.0, 91.0)		60.5 (51.0, 70.8)		70.0 (63.0, 80.5)		60.0 (44.0, 73.0)
Age, %, years^a
<60	817	56.5	3	2.5	99	49.0	22	18.5	941	49.9
60–74	356	24.6	30	25.4	72	35.6	52	43.7	510	27.1
>74	272	18.8	85	72.0	31	15.3	45	37.8	433	23.0
Race, %^a
White	376	26.0	59	50.0	52	25.7	43	36.1	530	28.1
Black	499	34.5	39	33.1	80	39.6	47	39.5	665	35.3
Latinx/other	569	39.4	20	16.9	70	34.7	29	24.4	688	36.5
Missing data	1	0.1	0	0	0	0	0	0	1	0.1
Sex, %^c
Female	702	48.6	49	41.5	85	42.1	52	43.7	888	47.1
Male	743	51.4	69	58.5	117	57.9	67	56.3	996	52.9
Body mass index, %^a,^d
<18.5	35	2.4	12	10.2	4	2.0	2	1.7	53	2.8
18.5– 24.9	304	21.0	44	37.3	32	15.8	29	24.4	409	21.7
25.0–29.9	379	26.2	23	19.5	48	23.8	30	25.2	480	25.5
30.0–39.9	405	28.0	14	11.9	58	28.7	27	22.7	504	26.8
≥40.0	116	8.0	2	1.7	22	10.9	13	10.9	153	8.1
Missing data	206	14.3	23	19.5	38	18.8	18	15.1	285	15.1
Diabetes^a,^e	374	25.9	28	23.7	72	35.6	46	38.7	520	27.6
Smoking history, %^a
Current smoker	78	5.4	7	5.9	19	9.4	6	5.0	110	5.8
Former smoker	284	19.7	35	29.7	57	28.2	33	27.7	409	21.7
Never smoker	957	66.2	48	40.7	109	54.0	50	42.0	1,164	61.8
Missing data	126	8.7	28	23.7	17	8.4	30	25.2	201	10.7
CCI score, median (IQR)^a	1.00 [0, 2.00]		2.00 [1.00, 3.00]		1.00 [0, 3.00]		1.00 [1.00, 3.00]		1.00 [0, 2.00]
CCI score, %^a
0	658	45.5	14	11.9	74	36.6	27	22.7	773	41.0
1–2	580	40.1	56	47.5	76	37.6	59	49.6	771	40.9
3–4	170	11.8	38	32.2	35	17.3	20	16.8	263	14.0
>5	30	2.1	10	8.5	17	8.4	13	10.9	70	3.7
Missing data	7	0.5	0	0	0	0	0	0	7	0.4
Ever had DNR/DNI order, %^a	175	12.1	112	94.9	35	17.3	105	88.2	427	22.7

Abbreviations: CCI, Charlson Comorbidity Index; COVID-19, coronavirus disease 2019; IQR, interquartile range; DNI, do not intubate; DNR, do not resuscitate.

^a Comparison across 4 strata statistically significant such that P < 0.001.

^b Values expressed as median (IQR).

^c Comparison across 4 strata groups not statistically significant.

^d Calculated as weight (kg)/height (m²).

^e Diabetes history missing for 7 patients (0.4%).

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