FastQC | https://www.bioinformatics.babraham.ac.uk/projects/fastqc/ | Quality visualization | 2010 | 2019 | 5090 | [44] |
PRINSEQ | http://prinseq.sourceforge.net/ | Quality visualization and QC | 2011 | 2013 | 2930 | [45] |
Fastx-Toolkit | http://hannonlab.cshl.edu/fastx_toolkit/ | Quality visualization and QC | 2009 | 2014 | ~500 | [46] |
Cutadapt | https://github.com/marcelm/cutadapt | QC | 2010 | 2020 | 9194 | [47] |
Trimmomatic | http://www.usadellab.org/cms/index.php?page=trimmomatic | QC | 2014 | – | 18 221 | [48] |
AdapterRemoval | https://github.com/MikkelSchubert/adapterremoval | QC | 2012 | 2016 | ~800 | [49, 50] |
SOAPnuke | https://github.com/BGI-flexlab/SOAPnuke | QC | 2018 | 2020 | 200 | [51] |
AlienTrimmer | ftp://ftp.pasteur.fr/pub/gensoft/projects/AlienTrimmer/ | QC | 2013 | 2016 | 116 | [52] |
Fastp | https://github.com/OpenGene/fastp | QC | 2018 | – | 852 | [53] |
BBDuk | https://sourceforge.net/projects/bbmap/ | QC | 2014 | 2020 | – | [54] |
EA-Utils | https://expressionanalysis.github.io/ea-utils/ | QC | 2011 | 2015 | ~500 | [55] |
Reaper | http://www.ebi.ac.uk/~stijn/reaper | QC | 2013 | – | 236 | [56] |
Sickle | https://github.com/najoshi/sickle | QC | 2011 | 2014 | 320 | – |
NGS QC Toolkit | http://www.nipgr.ac.in/ngsqctoolkit.html | QC | 2012 | – | 1721 | [57] |
SeqPurge | https://github.com/imgag/ngs-bits | QC | 2016 | 2020 | 51 | [58] |
Atropos | https://github.com/jdidion/atropos | QC | 2017 | – | 53 | [59] |
Btrim | http://graphics.med.yale.edu/trim/ | QC | 2011 | 2014 | 355 | [60] |
cutPrimers | https://github.com/aakechin/cutPrimers | QC | 2017 | 2019 | 25 | [61] |
Flexbar | https://github.com/seqan/flexbar | QC | 2012 | 2017 | 421 | [62] |
leeHom | https://bioinf.eva.mpg.de/leehom/ | QC, read merging | 2014 | 2020 | 125 | [63] |
ngsShoRT | https://research.bioinformatics.udel.edu/genomics/ngsShoRT/ | QC | 2013 | – | 5 | [64] |
NxTrim | https://github.com/sequencing/NxTrim | QC | 2015 | 2018 | 106 | [65] |
PEAT | http://jhhung.github.io/PEAT | QC | 2015 | – | 37 | [66] |
pTrimmer | https://github.com/DMU-lilab/pTrimmer | QC | 2019 | 2020 | – | [67] |
QcReads | https://sourceforge.net/projects/qcreads/ | QC | 2013 | 2019 | 5 | [68] |
Qtrim | http://hiv.sanbi.ac.za/tools/qtrim | QC | 2014 | – | 24 | [69] |
Skewer | https://sourceforge.net/projects/skewer | QC | 2014 | 2016 | 552 | [70] |