| . | MSSA n = 211 . | MRSA n = 37 . | P-value . |
|---|---|---|---|
| Demographic characteristics, n (%) | |||
| Male sex | 125 (59) | 20 (54) | 0.56 |
| Gestational age, weeks, median (IQR)a | 31 (28-35) | 31 (30-34) | 0.71 |
| Birthweight, grams, median (IQR) | 1350 (960-2420) | 1350 (985-2150) | 0.68 |
| Vaginal delivery | 60 (28) | 9 (24) | 0.61 |
| In-hospital birth | 190 (90) | 36 (97) | 0.22 |
| Multiple gestation | 64 (30) | 13 (35) | 0.56 |
| Race | 0.19 | ||
| White | 120 (57) | 20 (54) | — |
| Black/African American | 45 (21) | 4 (11) | — |
| Asian | 10 (5) | 4 (11) | — |
| Unknown/Other | 36 (17) | 9 (24) | — |
| Ethnicity | 0.83 | ||
| Hispanic | 59 (28) | 11 (30) | — |
| Non-Hispanic | 91 (43) | 14 (38) | — |
| Unknown | 61 (29) | 12 (32) | — |
| Age at first positive surveillance culture, days, median (IQR) | 24 (13-40) | 18 (9-32) | 0.06 |
| Clinical characteristics, n (%) | |||
| Admitting diagnosis | |||
| Prematurity | 148 (70) | 26 (70) | 0.99 |
| Congenital disorder | 50 (24) | 8 (22) | — |
| Cardiovascular | 31 (15) | 5 (14) | 0.85 |
| Other congenital disorderb | 19 (9) | 3 (8) | 0.72 |
| Respiratory | 6 (3) | 2 (5) | 0.34 |
| Other diagnosisc | 5 (2) | 1 (3) | 1.00 |
| Procedures, devices, and antibiotic therapy within 2 wk prior to positive culture, n (%) | |||
| Surgical procedure | 19 (9) | 4 (11) | 0.76 |
| Mechanical ventilation | |||
| Invasive | 46 (22) | 6 (16) | 0.44 |
| Noninvasive | 154 (73) | 28 (76) | 0.73 |
| Central line | 88 (42) | 15 (41) | 0.89 |
| Nasogastric tube | 120 (57) | 20 (54) | 0.75 |
| Antibiotic therapy | 95 (45) | 23 (62) | 0.05 |
| Retinopathy of prematurity exam | 35 (17) | 4 (11) | 0.37 |
| Outcomes | |||
| Mortality | 4 (2) | 1 (3) | 0.56 |
| Developed Staphylococcus aureus infection | 12 (6) | 4 (11) | 0.27 |
| Length of stay, days, median (IQR) | 57 (31-88) | 58 (35-107) | 0.43 |
| . | MSSA n = 211 . | MRSA n = 37 . | P-value . |
|---|---|---|---|
| Demographic characteristics, n (%) | |||
| Male sex | 125 (59) | 20 (54) | 0.56 |
| Gestational age, weeks, median (IQR)a | 31 (28-35) | 31 (30-34) | 0.71 |
| Birthweight, grams, median (IQR) | 1350 (960-2420) | 1350 (985-2150) | 0.68 |
| Vaginal delivery | 60 (28) | 9 (24) | 0.61 |
| In-hospital birth | 190 (90) | 36 (97) | 0.22 |
| Multiple gestation | 64 (30) | 13 (35) | 0.56 |
| Race | 0.19 | ||
| White | 120 (57) | 20 (54) | — |
| Black/African American | 45 (21) | 4 (11) | — |
| Asian | 10 (5) | 4 (11) | — |
| Unknown/Other | 36 (17) | 9 (24) | — |
| Ethnicity | 0.83 | ||
| Hispanic | 59 (28) | 11 (30) | — |
| Non-Hispanic | 91 (43) | 14 (38) | — |
| Unknown | 61 (29) | 12 (32) | — |
| Age at first positive surveillance culture, days, median (IQR) | 24 (13-40) | 18 (9-32) | 0.06 |
| Clinical characteristics, n (%) | |||
| Admitting diagnosis | |||
| Prematurity | 148 (70) | 26 (70) | 0.99 |
| Congenital disorder | 50 (24) | 8 (22) | — |
| Cardiovascular | 31 (15) | 5 (14) | 0.85 |
| Other congenital disorderb | 19 (9) | 3 (8) | 0.72 |
| Respiratory | 6 (3) | 2 (5) | 0.34 |
| Other diagnosisc | 5 (2) | 1 (3) | 1.00 |
| Procedures, devices, and antibiotic therapy within 2 wk prior to positive culture, n (%) | |||
| Surgical procedure | 19 (9) | 4 (11) | 0.76 |
| Mechanical ventilation | |||
| Invasive | 46 (22) | 6 (16) | 0.44 |
| Noninvasive | 154 (73) | 28 (76) | 0.73 |
| Central line | 88 (42) | 15 (41) | 0.89 |
| Nasogastric tube | 120 (57) | 20 (54) | 0.75 |
| Antibiotic therapy | 95 (45) | 23 (62) | 0.05 |
| Retinopathy of prematurity exam | 35 (17) | 4 (11) | 0.37 |
| Outcomes | |||
| Mortality | 4 (2) | 1 (3) | 0.56 |
| Developed Staphylococcus aureus infection | 12 (6) | 4 (11) | 0.27 |
| Length of stay, days, median (IQR) | 57 (31-88) | 58 (35-107) | 0.43 |
Abbreviations: MSSA, methicillin-sensitive Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus; IQR, interquartile range.
aOne infant had missing gestational age information.
bOther congenital disorders included gastrointestinal disorders, neurologic disorders, congenital diaphragmatic hernia, congenital tongue anomaly, craniofacial bone abnormalities, gastroschisis, overgrowth syndrome, Pierre-Robin Sequence, and Trisomy 21.
cOther disorders included cyanosis, hypotonia, persistent vomiting, and neonatal abstinence syndrome.
| . | MSSA n = 211 . | MRSA n = 37 . | P-value . |
|---|---|---|---|
| Demographic characteristics, n (%) | |||
| Male sex | 125 (59) | 20 (54) | 0.56 |
| Gestational age, weeks, median (IQR)a | 31 (28-35) | 31 (30-34) | 0.71 |
| Birthweight, grams, median (IQR) | 1350 (960-2420) | 1350 (985-2150) | 0.68 |
| Vaginal delivery | 60 (28) | 9 (24) | 0.61 |
| In-hospital birth | 190 (90) | 36 (97) | 0.22 |
| Multiple gestation | 64 (30) | 13 (35) | 0.56 |
| Race | 0.19 | ||
| White | 120 (57) | 20 (54) | — |
| Black/African American | 45 (21) | 4 (11) | — |
| Asian | 10 (5) | 4 (11) | — |
| Unknown/Other | 36 (17) | 9 (24) | — |
| Ethnicity | 0.83 | ||
| Hispanic | 59 (28) | 11 (30) | — |
| Non-Hispanic | 91 (43) | 14 (38) | — |
| Unknown | 61 (29) | 12 (32) | — |
| Age at first positive surveillance culture, days, median (IQR) | 24 (13-40) | 18 (9-32) | 0.06 |
| Clinical characteristics, n (%) | |||
| Admitting diagnosis | |||
| Prematurity | 148 (70) | 26 (70) | 0.99 |
| Congenital disorder | 50 (24) | 8 (22) | — |
| Cardiovascular | 31 (15) | 5 (14) | 0.85 |
| Other congenital disorderb | 19 (9) | 3 (8) | 0.72 |
| Respiratory | 6 (3) | 2 (5) | 0.34 |
| Other diagnosisc | 5 (2) | 1 (3) | 1.00 |
| Procedures, devices, and antibiotic therapy within 2 wk prior to positive culture, n (%) | |||
| Surgical procedure | 19 (9) | 4 (11) | 0.76 |
| Mechanical ventilation | |||
| Invasive | 46 (22) | 6 (16) | 0.44 |
| Noninvasive | 154 (73) | 28 (76) | 0.73 |
| Central line | 88 (42) | 15 (41) | 0.89 |
| Nasogastric tube | 120 (57) | 20 (54) | 0.75 |
| Antibiotic therapy | 95 (45) | 23 (62) | 0.05 |
| Retinopathy of prematurity exam | 35 (17) | 4 (11) | 0.37 |
| Outcomes | |||
| Mortality | 4 (2) | 1 (3) | 0.56 |
| Developed Staphylococcus aureus infection | 12 (6) | 4 (11) | 0.27 |
| Length of stay, days, median (IQR) | 57 (31-88) | 58 (35-107) | 0.43 |
| . | MSSA n = 211 . | MRSA n = 37 . | P-value . |
|---|---|---|---|
| Demographic characteristics, n (%) | |||
| Male sex | 125 (59) | 20 (54) | 0.56 |
| Gestational age, weeks, median (IQR)a | 31 (28-35) | 31 (30-34) | 0.71 |
| Birthweight, grams, median (IQR) | 1350 (960-2420) | 1350 (985-2150) | 0.68 |
| Vaginal delivery | 60 (28) | 9 (24) | 0.61 |
| In-hospital birth | 190 (90) | 36 (97) | 0.22 |
| Multiple gestation | 64 (30) | 13 (35) | 0.56 |
| Race | 0.19 | ||
| White | 120 (57) | 20 (54) | — |
| Black/African American | 45 (21) | 4 (11) | — |
| Asian | 10 (5) | 4 (11) | — |
| Unknown/Other | 36 (17) | 9 (24) | — |
| Ethnicity | 0.83 | ||
| Hispanic | 59 (28) | 11 (30) | — |
| Non-Hispanic | 91 (43) | 14 (38) | — |
| Unknown | 61 (29) | 12 (32) | — |
| Age at first positive surveillance culture, days, median (IQR) | 24 (13-40) | 18 (9-32) | 0.06 |
| Clinical characteristics, n (%) | |||
| Admitting diagnosis | |||
| Prematurity | 148 (70) | 26 (70) | 0.99 |
| Congenital disorder | 50 (24) | 8 (22) | — |
| Cardiovascular | 31 (15) | 5 (14) | 0.85 |
| Other congenital disorderb | 19 (9) | 3 (8) | 0.72 |
| Respiratory | 6 (3) | 2 (5) | 0.34 |
| Other diagnosisc | 5 (2) | 1 (3) | 1.00 |
| Procedures, devices, and antibiotic therapy within 2 wk prior to positive culture, n (%) | |||
| Surgical procedure | 19 (9) | 4 (11) | 0.76 |
| Mechanical ventilation | |||
| Invasive | 46 (22) | 6 (16) | 0.44 |
| Noninvasive | 154 (73) | 28 (76) | 0.73 |
| Central line | 88 (42) | 15 (41) | 0.89 |
| Nasogastric tube | 120 (57) | 20 (54) | 0.75 |
| Antibiotic therapy | 95 (45) | 23 (62) | 0.05 |
| Retinopathy of prematurity exam | 35 (17) | 4 (11) | 0.37 |
| Outcomes | |||
| Mortality | 4 (2) | 1 (3) | 0.56 |
| Developed Staphylococcus aureus infection | 12 (6) | 4 (11) | 0.27 |
| Length of stay, days, median (IQR) | 57 (31-88) | 58 (35-107) | 0.43 |
Abbreviations: MSSA, methicillin-sensitive Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus; IQR, interquartile range.
aOne infant had missing gestational age information.
bOther congenital disorders included gastrointestinal disorders, neurologic disorders, congenital diaphragmatic hernia, congenital tongue anomaly, craniofacial bone abnormalities, gastroschisis, overgrowth syndrome, Pierre-Robin Sequence, and Trisomy 21.
cOther disorders included cyanosis, hypotonia, persistent vomiting, and neonatal abstinence syndrome.
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