Table 3.

Safety outcomes

ToxicityProphylaxis patients N =47, n (%)Treatment patients N =48, n (%)
Leucopenia
 WBC count <3.5 × 109/L8 (17); 8 SOT27 (56); 7 SOT and 20 HSCT
 WBC count >20% decrease from baseline24 (51); 24 SOT24 (50); 7 SOT and 17 HSCT
Thrombocytopenia
 platelet count <100 × 109/L17 (36); 17 SOT31 (65); 3 SOT and 28 HSCT
 platelet count >50% decrease from baseline4 (9); 4 SOT9 (19); 1 SOT and 8 HSCT
ToxicityProphylaxis patients N =47, n (%)Treatment patients N =48, n (%)
Leucopenia
 WBC count <3.5 × 109/L8 (17); 8 SOT27 (56); 7 SOT and 20 HSCT
 WBC count >20% decrease from baseline24 (51); 24 SOT24 (50); 7 SOT and 17 HSCT
Thrombocytopenia
 platelet count <100 × 109/L17 (36); 17 SOT31 (65); 3 SOT and 28 HSCT
 platelet count >50% decrease from baseline4 (9); 4 SOT9 (19); 1 SOT and 8 HSCT

WBC count normal range = 4–10 × 109/L.

Platelet count normal range = 150–400 × 109/L.

Table 3.

Safety outcomes

ToxicityProphylaxis patients N =47, n (%)Treatment patients N =48, n (%)
Leucopenia
 WBC count <3.5 × 109/L8 (17); 8 SOT27 (56); 7 SOT and 20 HSCT
 WBC count >20% decrease from baseline24 (51); 24 SOT24 (50); 7 SOT and 17 HSCT
Thrombocytopenia
 platelet count <100 × 109/L17 (36); 17 SOT31 (65); 3 SOT and 28 HSCT
 platelet count >50% decrease from baseline4 (9); 4 SOT9 (19); 1 SOT and 8 HSCT
ToxicityProphylaxis patients N =47, n (%)Treatment patients N =48, n (%)
Leucopenia
 WBC count <3.5 × 109/L8 (17); 8 SOT27 (56); 7 SOT and 20 HSCT
 WBC count >20% decrease from baseline24 (51); 24 SOT24 (50); 7 SOT and 17 HSCT
Thrombocytopenia
 platelet count <100 × 109/L17 (36); 17 SOT31 (65); 3 SOT and 28 HSCT
 platelet count >50% decrease from baseline4 (9); 4 SOT9 (19); 1 SOT and 8 HSCT

WBC count normal range = 4–10 × 109/L.

Platelet count normal range = 150–400 × 109/L.

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