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Table 1

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The distributions of IL1β and ILRN gene polymorphisms and haplotypes in H. pylori positive and negative patients

	H. pylori				χ² or FE	p value
	Positive (n = 50)		Negative (n = 50)
	No.	%	No.	%
IL1β-31 genotype					0.455	1.000
C/C	1	2.0	2	4.0
C/T	30	60.0	30	60.0
T/T	19	38.0	18	36.0
IL1β-31 allele					0.090	0.764
C	32	32.0	34	34.0
T	68	68.0	66	66.0
IL1β-511 genotype					19.947^*	0.001^*
C/C	9	18.0	19	38.0
C/T	36	72.0	14	28.0
T/T	5	10.0	17	34.0
IL1β-511 allele					0.080	0.777
C	54	54.0	52	52.0
T	46	46.0	48	48.0
ILRN genotype					1.052	0.811
2/2	0	0.0	1	2.0
2/L	11	22.0	12	24.0
L/L	39	78.0	37	74.0
ILRN allele					0.411	0.521
2	11	11.0	14	14.0
L	89	89.0	86	86.0
Number of polymorphisms
Absent	8	16.0	12	24.0
One	14	28.0	25	50.0	10.063^*	0.018^*
Two	21	42.0	8	16.0
Three	7	14.0	5	10.0
Haplotypes
C-C-2		8.0		6.0	0.332	0.564
C-C-L		20.0		15.0	1.099	0.295
T-C-2		2.0		1.0	0.344	1.000
T-C-L		24.0		30.0	1.449	0.229
C-T-2		1.0		3.0	1.042	0.617
C-T-L		3.0		10.0	4.332^*	0.037*
T-T-2		0.0		4.0	4.167	0.117
T-T-L		42.0		31.0	6.139^*	0.013*

	H. pylori				χ² or FE	p value
	Positive (n = 50)		Negative (n = 50)
	No.	%	No.	%
IL1β-31 genotype					0.455	1.000
C/C	1	2.0	2	4.0
C/T	30	60.0	30	60.0
T/T	19	38.0	18	36.0
IL1β-31 allele					0.090	0.764
C	32	32.0	34	34.0
T	68	68.0	66	66.0
IL1β-511 genotype					19.947^*	0.001^*
C/C	9	18.0	19	38.0
C/T	36	72.0	14	28.0
T/T	5	10.0	17	34.0
IL1β-511 allele					0.080	0.777
C	54	54.0	52	52.0
T	46	46.0	48	48.0
ILRN genotype					1.052	0.811
2/2	0	0.0	1	2.0
2/L	11	22.0	12	24.0
L/L	39	78.0	37	74.0
ILRN allele					0.411	0.521
2	11	11.0	14	14.0
L	89	89.0	86	86.0
Number of polymorphisms
Absent	8	16.0	12	24.0
One	14	28.0	25	50.0	10.063^*	0.018^*
Two	21	42.0	8	16.0
Three	7	14.0	5	10.0
Haplotypes
C-C-2		8.0		6.0	0.332	0.564
C-C-L		20.0		15.0	1.099	0.295
T-C-2		2.0		1.0	0.344	1.000
T-C-L		24.0		30.0	1.449	0.229
C-T-2		1.0		3.0	1.042	0.617
C-T-L		3.0		10.0	4.332^*	0.037*
T-T-2		0.0		4.0	4.167	0.117
T-T-L		42.0		31.0	6.139^*	0.013*

Combination of alleles in each haplotype is in the following order: (IL1β-31/IL1β-511/ILRN).

χ², Chi square test. FE, Fisher exact.

Statistically significant at p ≤ 0.05.

Table 1

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The distributions of IL1β and ILRN gene polymorphisms and haplotypes in H. pylori positive and negative patients

	H. pylori				χ² or FE	p value
	Positive (n = 50)		Negative (n = 50)
	No.	%	No.	%
IL1β-31 genotype					0.455	1.000
C/C	1	2.0	2	4.0
C/T	30	60.0	30	60.0
T/T	19	38.0	18	36.0
IL1β-31 allele					0.090	0.764
C	32	32.0	34	34.0
T	68	68.0	66	66.0
IL1β-511 genotype					19.947^*	0.001^*
C/C	9	18.0	19	38.0
C/T	36	72.0	14	28.0
T/T	5	10.0	17	34.0
IL1β-511 allele					0.080	0.777
C	54	54.0	52	52.0
T	46	46.0	48	48.0
ILRN genotype					1.052	0.811
2/2	0	0.0	1	2.0
2/L	11	22.0	12	24.0
L/L	39	78.0	37	74.0
ILRN allele					0.411	0.521
2	11	11.0	14	14.0
L	89	89.0	86	86.0
Number of polymorphisms
Absent	8	16.0	12	24.0
One	14	28.0	25	50.0	10.063^*	0.018^*
Two	21	42.0	8	16.0
Three	7	14.0	5	10.0
Haplotypes
C-C-2		8.0		6.0	0.332	0.564
C-C-L		20.0		15.0	1.099	0.295
T-C-2		2.0		1.0	0.344	1.000
T-C-L		24.0		30.0	1.449	0.229
C-T-2		1.0		3.0	1.042	0.617
C-T-L		3.0		10.0	4.332^*	0.037*
T-T-2		0.0		4.0	4.167	0.117
T-T-L		42.0		31.0	6.139^*	0.013*

	H. pylori				χ² or FE	p value
	Positive (n = 50)		Negative (n = 50)
	No.	%	No.	%
IL1β-31 genotype					0.455	1.000
C/C	1	2.0	2	4.0
C/T	30	60.0	30	60.0
T/T	19	38.0	18	36.0
IL1β-31 allele					0.090	0.764
C	32	32.0	34	34.0
T	68	68.0	66	66.0
IL1β-511 genotype					19.947^*	0.001^*
C/C	9	18.0	19	38.0
C/T	36	72.0	14	28.0
T/T	5	10.0	17	34.0
IL1β-511 allele					0.080	0.777
C	54	54.0	52	52.0
T	46	46.0	48	48.0
ILRN genotype					1.052	0.811
2/2	0	0.0	1	2.0
2/L	11	22.0	12	24.0
L/L	39	78.0	37	74.0
ILRN allele					0.411	0.521
2	11	11.0	14	14.0
L	89	89.0	86	86.0
Number of polymorphisms
Absent	8	16.0	12	24.0
One	14	28.0	25	50.0	10.063^*	0.018^*
Two	21	42.0	8	16.0
Three	7	14.0	5	10.0
Haplotypes
C-C-2		8.0		6.0	0.332	0.564
C-C-L		20.0		15.0	1.099	0.295
T-C-2		2.0		1.0	0.344	1.000
T-C-L		24.0		30.0	1.449	0.229
C-T-2		1.0		3.0	1.042	0.617
C-T-L		3.0		10.0	4.332^*	0.037*
T-T-2		0.0		4.0	4.167	0.117
T-T-L		42.0		31.0	6.139^*	0.013*

Combination of alleles in each haplotype is in the following order: (IL1β-31/IL1β-511/ILRN).

χ², Chi square test. FE, Fisher exact.

Statistically significant at p ≤ 0.05.