Table 2. Open in new tab Demographics of...

Table 2.

Demographics of Germinoma Patients With Positive Cytology Treated with CSI and Non-CSI

	CSI (n = 11)	non-CSI (n = 11)	P-value
Age at diagnosis, range (median), years	7–40 (12)	9–28 (16)	.94^b
Sex, male:female	7:3	7:4	1.00^a
Location			.15^a
Pineal	1	4
Neurohypophysis	1	2
Basal ganglia	0	1
Bifocal	9	4
CSF sampling			.66
Lumbar tap	5	3
Ventricle	6	8
HCG/HCG-β elevation			.18^a
Yes	9	5
No	2	6
Verification of histological diagnosis			1.00^a
Unverified	3	4
Verified	8	7
Histological diagnosis			.47^a
Pure germinoma	8	6
Germinoma with STGC	0	1
Radiation field
Whole ventricle	0	5
Whole brain	0	6
CSI	11	0
Radiation dose, range (median), Gy
Primary site	24–52 (44)	24–51 (40)	.39^b
Whole ventricle	23–44 (24)	24–45 (30)	.57^b
Whole brain	23–32 (24)	10–45 (30)	.31^b
Craniospinal	18–35 (24)	0
Chemotherapy			1.00^a
Yes	8	7
No	3	4
Follow-up periods, range (median), months	12–265 (101)	2–228 (75)	.25^b

	CSI (n = 11)	non-CSI (n = 11)	P-value
Age at diagnosis, range (median), years	7–40 (12)	9–28 (16)	.94^b
Sex, male:female	7:3	7:4	1.00^a
Location			.15^a
Pineal	1	4
Neurohypophysis	1	2
Basal ganglia	0	1
Bifocal	9	4
CSF sampling			.66
Lumbar tap	5	3
Ventricle	6	8
HCG/HCG-β elevation			.18^a
Yes	9	5
No	2	6
Verification of histological diagnosis			1.00^a
Unverified	3	4
Verified	8	7
Histological diagnosis			.47^a
Pure germinoma	8	6
Germinoma with STGC	0	1
Radiation field
Whole ventricle	0	5
Whole brain	0	6
CSI	11	0
Radiation dose, range (median), Gy
Primary site	24–52 (44)	24–51 (40)	.39^b
Whole ventricle	23–44 (24)	24–45 (30)	.57^b
Whole brain	23–32 (24)	10–45 (30)	.31^b
Craniospinal	18–35 (24)	0
Chemotherapy			1.00^a
Yes	8	7
No	3	4
Follow-up periods, range (median), months	12–265 (101)	2–228 (75)	.25^b

CSI, craniospinal irradiation; STGC, syncytiotrophoblastic giant cell.

^aFisher’s exact test;

^bStudent’s t-test.