| Subtotal Resection for Newly Diagnosed Atypical Meningioma . | Postoperative Upfront RT (n = 15) . | Postoperative Observation (n = 15) . | . |
|---|---|---|---|
| Age at diagnosis, median, years (IQR) | 56 (17) | 73 (19) | P = .08 |
| Female, n (%) | 9 (60%) | 7 (47%) | |
| Follow-up, median, months (IQR) | 65 (56) | 39 (42) | P = .35 |
| Simpson | |||
| IV | 15 | 15 | |
| V | 0 | 0 | |
| Location | |||
| Convexity/parasagittal | 7 | 8 | χ 2P = 1 |
| Other | 8 | 7 | |
| Mitotic count, median (IQR) | 4 (0) | 6 (3) | P = .1 |
| EBRT regimens, total dose/fractions (n) | 50.4 Gy/28 fx (1); 54 Gy/30 fx (2); 59.4 Gy/33 fx (3); 60 Gy/30 fx (2); 60.4 Gy/33 fx (1); unspecified (1) | ||
| SRS regimens, total dose/fractions (n) | 25 Gy/5 fx (2); 30 Gy/6 fx (1); 33 Gy/3 fx (2) |
| Subtotal Resection for Newly Diagnosed Atypical Meningioma . | Postoperative Upfront RT (n = 15) . | Postoperative Observation (n = 15) . | . |
|---|---|---|---|
| Age at diagnosis, median, years (IQR) | 56 (17) | 73 (19) | P = .08 |
| Female, n (%) | 9 (60%) | 7 (47%) | |
| Follow-up, median, months (IQR) | 65 (56) | 39 (42) | P = .35 |
| Simpson | |||
| IV | 15 | 15 | |
| V | 0 | 0 | |
| Location | |||
| Convexity/parasagittal | 7 | 8 | χ 2P = 1 |
| Other | 8 | 7 | |
| Mitotic count, median (IQR) | 4 (0) | 6 (3) | P = .1 |
| EBRT regimens, total dose/fractions (n) | 50.4 Gy/28 fx (1); 54 Gy/30 fx (2); 59.4 Gy/33 fx (3); 60 Gy/30 fx (2); 60.4 Gy/33 fx (1); unspecified (1) | ||
| SRS regimens, total dose/fractions (n) | 25 Gy/5 fx (2); 30 Gy/6 fx (1); 33 Gy/3 fx (2) |
No statistically significant differences between upfront and non-upfront RT cases, although median age of non-RT group was higher. “Other” locations include meningiomas in anterior skull base, foramen magnum, posterior fossa, sella, sphenoid wing, and tentorium. EBRT, external beam radiotherapy; IQR, interquartile range; RT, radiotherapy; SRS, stereotactic radiosurgery.
| Subtotal Resection for Newly Diagnosed Atypical Meningioma . | Postoperative Upfront RT (n = 15) . | Postoperative Observation (n = 15) . | . |
|---|---|---|---|
| Age at diagnosis, median, years (IQR) | 56 (17) | 73 (19) | P = .08 |
| Female, n (%) | 9 (60%) | 7 (47%) | |
| Follow-up, median, months (IQR) | 65 (56) | 39 (42) | P = .35 |
| Simpson | |||
| IV | 15 | 15 | |
| V | 0 | 0 | |
| Location | |||
| Convexity/parasagittal | 7 | 8 | χ 2P = 1 |
| Other | 8 | 7 | |
| Mitotic count, median (IQR) | 4 (0) | 6 (3) | P = .1 |
| EBRT regimens, total dose/fractions (n) | 50.4 Gy/28 fx (1); 54 Gy/30 fx (2); 59.4 Gy/33 fx (3); 60 Gy/30 fx (2); 60.4 Gy/33 fx (1); unspecified (1) | ||
| SRS regimens, total dose/fractions (n) | 25 Gy/5 fx (2); 30 Gy/6 fx (1); 33 Gy/3 fx (2) |
| Subtotal Resection for Newly Diagnosed Atypical Meningioma . | Postoperative Upfront RT (n = 15) . | Postoperative Observation (n = 15) . | . |
|---|---|---|---|
| Age at diagnosis, median, years (IQR) | 56 (17) | 73 (19) | P = .08 |
| Female, n (%) | 9 (60%) | 7 (47%) | |
| Follow-up, median, months (IQR) | 65 (56) | 39 (42) | P = .35 |
| Simpson | |||
| IV | 15 | 15 | |
| V | 0 | 0 | |
| Location | |||
| Convexity/parasagittal | 7 | 8 | χ 2P = 1 |
| Other | 8 | 7 | |
| Mitotic count, median (IQR) | 4 (0) | 6 (3) | P = .1 |
| EBRT regimens, total dose/fractions (n) | 50.4 Gy/28 fx (1); 54 Gy/30 fx (2); 59.4 Gy/33 fx (3); 60 Gy/30 fx (2); 60.4 Gy/33 fx (1); unspecified (1) | ||
| SRS regimens, total dose/fractions (n) | 25 Gy/5 fx (2); 30 Gy/6 fx (1); 33 Gy/3 fx (2) |
No statistically significant differences between upfront and non-upfront RT cases, although median age of non-RT group was higher. “Other” locations include meningiomas in anterior skull base, foramen magnum, posterior fossa, sella, sphenoid wing, and tentorium. EBRT, external beam radiotherapy; IQR, interquartile range; RT, radiotherapy; SRS, stereotactic radiosurgery.
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