Table 2 Open in new tab CMR...

	Inducible ischaemia– (N = 528)	Inducible ischaemia+ (N = 131)	P value
Cardiac rhythm, n (%)
Sinus rhythm	492 (93.2)	123 (93.9)	0.77
Sinus rhythm with extrasystoles	2 (0.4)	1 (0.8)	0.98
Atrial fibrillation/supraventricular arrhythmias	34 (6.4)	7 (5.3)	0.72
LV ejection fraction (%)	60.2 ± 8.7	56.2 ± 10.8	<0.001
LV end-diastolic volume index (mL/m²)	71.2 ± 19.9	70.9 ± 19.9	0.56
LV end-systolic volume index (mL/m²)	28.6 ± 11.2	30.3 ± 11.6	0.21
LV systolic ejection volume index (mL/m²)	42.1 ± 13.2	40.5 ± 13.8	0.03
LV mass (g/m²)	74.7 ± 6.2	72.4 ± 10.1	0.29
RV ejection fraction (%)	59.3 ± 11.9	57.1 ± 13.7	0.34
RV end-diastolic volume index (mL/m²)	70.2 ± 9.8	72.8 ± 12.1	0.56
RV end-systolic volume index (mL/m²)	21.8 ± 5.3	23.9 ± 6.2	0.49
Resting wall motion abnormality, n (%)	28 (5.3)	8 (6.1)	0.82
Wall motion abnormality during peak of the vasodilator stress, n (%)	37 (7.0)	70 (53.4)	<0.0001
Presence of LGE, n (%)	22 (4.2)	47 (35.9)	<0.0001
Number of segments with LGE	2.6 ± 1.2	2.6 ± 1.7	0.87
Presence of viability,^an (%)	17 (3.2)	45 (34.4)	<0.0001
Number of segments with inducible ischaemia	0.0 ± 0.0	3.8 ± 1.1	<0.0001
RPP at baseline (mmHg/bpm)	9.34 (7.78–10.91)	9.39 (7.81–11.30)	0.48
RPP at stress (mmHg/bpm)	10.37 (8.76–12.14)	11.10 (9.76–13.27) 0.08

Inducible ischaemia– (N = 528)

Inducible ischaemia+ (N = 131)

P value

Cardiac rhythm, n (%)

Sinus rhythm

492 (93.2)

123 (93.9)

0.77

Sinus rhythm with extrasystoles

2 (0.4)

1 (0.8)

0.98

Atrial fibrillation/supraventricular arrhythmias

34 (6.4)

7 (5.3)

0.72

LV ejection fraction (%)

60.2 ± 8.7

56.2 ± 10.8

<0.001

LV end-diastolic volume index (mL/m²)

71.2 ± 19.9

70.9 ± 19.9

0.56

LV end-systolic volume index (mL/m²)

28.6 ± 11.2

30.3 ± 11.6

0.21

LV systolic ejection volume index (mL/m²)

42.1 ± 13.2

40.5 ± 13.8

0.03

LV mass (g/m²)

74.7 ± 6.2

72.4 ± 10.1

0.29

RV ejection fraction (%)

59.3 ± 11.9

57.1 ± 13.7

0.34

RV end-diastolic volume index (mL/m²)

70.2 ± 9.8

72.8 ± 12.1

0.56

RV end-systolic volume index (mL/m²)

21.8 ± 5.3

23.9 ± 6.2

0.49

Resting wall motion abnormality, n (%)

28 (5.3)

8 (6.1)

0.82

Wall motion abnormality during peak of the vasodilator stress, n (%)

37 (7.0)

70 (53.4)

<0.0001

Presence of LGE, n (%)

22 (4.2)

47 (35.9)

<0.0001

Number of segments with LGE

2.6 ± 1.2

2.6 ± 1.7

0.87

Presence of viability,^an (%)

17 (3.2)

45 (34.4)

<0.0001

Number of segments with inducible ischaemia

0.0 ± 0.0

3.8 ± 1.1

<0.0001

RPP at baseline (mmHg/bpm)

9.34 (7.78–10.91)

9.39 (7.81–11.30)

0.48

RPP at stress (mmHg/bpm)

10.37 (8.76–12.14)

11.10 (9.76–13.27) 0.08

	Inducible ischaemia– (N = 528)	Inducible ischaemia+ (N = 131)	P value
Cardiac rhythm, n (%)
Sinus rhythm	492 (93.2)	123 (93.9)	0.77
Sinus rhythm with extrasystoles	2 (0.4)	1 (0.8)	0.98
Atrial fibrillation/supraventricular arrhythmias	34 (6.4)	7 (5.3)	0.72
LV ejection fraction (%)	60.2 ± 8.7	56.2 ± 10.8	<0.001
LV end-diastolic volume index (mL/m²)	71.2 ± 19.9	70.9 ± 19.9	0.56
LV end-systolic volume index (mL/m²)	28.6 ± 11.2	30.3 ± 11.6	0.21
LV systolic ejection volume index (mL/m²)	42.1 ± 13.2	40.5 ± 13.8	0.03
LV mass (g/m²)	74.7 ± 6.2	72.4 ± 10.1	0.29
RV ejection fraction (%)	59.3 ± 11.9	57.1 ± 13.7	0.34
RV end-diastolic volume index (mL/m²)	70.2 ± 9.8	72.8 ± 12.1	0.56
RV end-systolic volume index (mL/m²)	21.8 ± 5.3	23.9 ± 6.2	0.49
Resting wall motion abnormality, n (%)	28 (5.3)	8 (6.1)	0.82
Wall motion abnormality during peak of the vasodilator stress, n (%)	37 (7.0)	70 (53.4)	<0.0001
Presence of LGE, n (%)	22 (4.2)	47 (35.9)	<0.0001
Number of segments with LGE	2.6 ± 1.2	2.6 ± 1.7	0.87
Presence of viability,^an (%)	17 (3.2)	45 (34.4)	<0.0001
Number of segments with inducible ischaemia	0.0 ± 0.0	3.8 ± 1.1	<0.0001
RPP at baseline (mmHg/bpm)	9.34 (7.78–10.91)	9.39 (7.81–11.30)	0.48
RPP at stress (mmHg/bpm)	10.37 (8.76–12.14)	11.10 (9.76–13.27) 0.08

Table 2

Open in new tab

CMR characteristics of patients (n = 659)

	Inducible ischaemia– (N = 528)	Inducible ischaemia+ (N = 131)	P value
Cardiac rhythm, n (%)
Sinus rhythm	492 (93.2)	123 (93.9)	0.77
Sinus rhythm with extrasystoles	2 (0.4)	1 (0.8)	0.98
Atrial fibrillation/supraventricular arrhythmias	34 (6.4)	7 (5.3)	0.72
LV ejection fraction (%)	60.2 ± 8.7	56.2 ± 10.8	<0.001
LV end-diastolic volume index (mL/m²)	71.2 ± 19.9	70.9 ± 19.9	0.56
LV end-systolic volume index (mL/m²)	28.6 ± 11.2	30.3 ± 11.6	0.21
LV systolic ejection volume index (mL/m²)	42.1 ± 13.2	40.5 ± 13.8	0.03
LV mass (g/m²)	74.7 ± 6.2	72.4 ± 10.1	0.29
RV ejection fraction (%)	59.3 ± 11.9	57.1 ± 13.7	0.34
RV end-diastolic volume index (mL/m²)	70.2 ± 9.8	72.8 ± 12.1	0.56
RV end-systolic volume index (mL/m²)	21.8 ± 5.3	23.9 ± 6.2	0.49
Resting wall motion abnormality, n (%)	28 (5.3)	8 (6.1)	0.82
Wall motion abnormality during peak of the vasodilator stress, n (%)	37 (7.0)	70 (53.4)	<0.0001
Presence of LGE, n (%)	22 (4.2)	47 (35.9)	<0.0001
Number of segments with LGE	2.6 ± 1.2	2.6 ± 1.7	0.87
Presence of viability,^an (%)	17 (3.2)	45 (34.4)	<0.0001
Number of segments with inducible ischaemia	0.0 ± 0.0	3.8 ± 1.1	<0.0001
RPP at baseline (mmHg/bpm)	9.34 (7.78–10.91)	9.39 (7.81–11.30)	0.48
RPP at stress (mmHg/bpm)	10.37 (8.76–12.14)	11.10 (9.76–13.27) 0.08

	Inducible ischaemia– (N = 528)	Inducible ischaemia+ (N = 131)	P value
Cardiac rhythm, n (%)
Sinus rhythm	492 (93.2)	123 (93.9)	0.77
Sinus rhythm with extrasystoles	2 (0.4)	1 (0.8)	0.98
Atrial fibrillation/supraventricular arrhythmias	34 (6.4)	7 (5.3)	0.72
LV ejection fraction (%)	60.2 ± 8.7	56.2 ± 10.8	<0.001
LV end-diastolic volume index (mL/m²)	71.2 ± 19.9	70.9 ± 19.9	0.56
LV end-systolic volume index (mL/m²)	28.6 ± 11.2	30.3 ± 11.6	0.21
LV systolic ejection volume index (mL/m²)	42.1 ± 13.2	40.5 ± 13.8	0.03
LV mass (g/m²)	74.7 ± 6.2	72.4 ± 10.1	0.29
RV ejection fraction (%)	59.3 ± 11.9	57.1 ± 13.7	0.34
RV end-diastolic volume index (mL/m²)	70.2 ± 9.8	72.8 ± 12.1	0.56
RV end-systolic volume index (mL/m²)	21.8 ± 5.3	23.9 ± 6.2	0.49
Resting wall motion abnormality, n (%)	28 (5.3)	8 (6.1)	0.82
Wall motion abnormality during peak of the vasodilator stress, n (%)	37 (7.0)	70 (53.4)	<0.0001
Presence of LGE, n (%)	22 (4.2)	47 (35.9)	<0.0001
Number of segments with LGE	2.6 ± 1.2	2.6 ± 1.7	0.87
Presence of viability,^an (%)	17 (3.2)	45 (34.4)	<0.0001
Number of segments with inducible ischaemia	0.0 ± 0.0	3.8 ± 1.1	<0.0001
RPP at baseline (mmHg/bpm)	9.34 (7.78–10.91)	9.39 (7.81–11.30)	0.48
RPP at stress (mmHg/bpm)	10.37 (8.76–12.14)	11.10 (9.76–13.27) 0.08

Values are expressed as n (%), mean ± SD, or median (interquartile range).

+, with ischaemia; –, without ischaemia; CMR, cardiovascular magnetic resonance; LA, left atrium; LGE, late gadolinium enhancement; RPP, rate-pressure product (pressure mmHg × heart rate bpm)/1000.

Defined by the presence of LGE with <50% transmurality.²⁴

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