Epidemiologic and Clinical Characteristics of Patients With Invasive Haemophilus influenzae Serotype a Disease—United States and Alaska, 2008–2017
| Characteristics . | United Statesa (N = 386) . | Alaska(N = 49) . |
|---|---|---|
| Age in years, median (range) | 30 (0–92) | 1 (0–77) |
| Sex, % | ||
| Male | 50.0 | 61.2 |
| Race, % | ||
| White | 59.3 | 4.1 |
| Black | 14.8 | 0.0 |
| AI/AN | 14.8 | 93.9 |
| Asian/PI | 1.3 | 2.0 |
| Unknown | 9.8 | 0.0 |
| Ethnicity, % | ||
| Hispanic/Latino | 15.0 | N/A |
| Non-Hispanic/Latino | 68.1 | N/A |
| Unknown | 16.8 | N/A |
| Clinical syndrome,b % | ||
| Bacteremic pneumonia | 41.3 | 18.4 |
| Bacteremia | 32.0 | 12.2 |
| Meningitis | 23.9 | 38.8 |
| Septic arthritis | 7.8 | 16.3 |
| Cellulitis | 4.4 | 12.2 |
| Epiglottitis | 3.9 | 0.0 |
| Other invasive disease | 0.5 | 2.1 |
| Hospitalized, % | 94.8 | 87.8 |
| Duration of hospitalization in days, median (range) | 7 (0–126) | 8 (0–68) |
| Died,c % | 7.8 | 10.2 |
| Characteristics . | United Statesa (N = 386) . | Alaska(N = 49) . |
|---|---|---|
| Age in years, median (range) | 30 (0–92) | 1 (0–77) |
| Sex, % | ||
| Male | 50.0 | 61.2 |
| Race, % | ||
| White | 59.3 | 4.1 |
| Black | 14.8 | 0.0 |
| AI/AN | 14.8 | 93.9 |
| Asian/PI | 1.3 | 2.0 |
| Unknown | 9.8 | 0.0 |
| Ethnicity, % | ||
| Hispanic/Latino | 15.0 | N/A |
| Non-Hispanic/Latino | 68.1 | N/A |
| Unknown | 16.8 | N/A |
| Clinical syndrome,b % | ||
| Bacteremic pneumonia | 41.3 | 18.4 |
| Bacteremia | 32.0 | 12.2 |
| Meningitis | 23.9 | 38.8 |
| Septic arthritis | 7.8 | 16.3 |
| Cellulitis | 4.4 | 12.2 |
| Epiglottitis | 3.9 | 0.0 |
| Other invasive disease | 0.5 | 2.1 |
| Hospitalized, % | 94.8 | 87.8 |
| Duration of hospitalization in days, median (range) | 7 (0–126) | 8 (0–68) |
| Died,c % | 7.8 | 10.2 |
Abbreviations: AI/AN, American Indian and Alaska Native; N/A, not available; PI, Pacific Islander.
aNote: data shown in this column are from Active Bacterial Core surveillance sites and do not include all cases in the United States.
bInformation on clinical syndrome was available for 385/386 (99.7%) cases in the United States and 49/49 (100%) cases in Alaska. Clinical syndrome was not mutually exclusive.
cInformation on outcome was available for 384/386 (99.5%) cases in the United States and 49/49 (100%) cases in Alaska.
Epidemiologic and Clinical Characteristics of Patients With Invasive Haemophilus influenzae Serotype a Disease—United States and Alaska, 2008–2017
| Characteristics . | United Statesa (N = 386) . | Alaska(N = 49) . |
|---|---|---|
| Age in years, median (range) | 30 (0–92) | 1 (0–77) |
| Sex, % | ||
| Male | 50.0 | 61.2 |
| Race, % | ||
| White | 59.3 | 4.1 |
| Black | 14.8 | 0.0 |
| AI/AN | 14.8 | 93.9 |
| Asian/PI | 1.3 | 2.0 |
| Unknown | 9.8 | 0.0 |
| Ethnicity, % | ||
| Hispanic/Latino | 15.0 | N/A |
| Non-Hispanic/Latino | 68.1 | N/A |
| Unknown | 16.8 | N/A |
| Clinical syndrome,b % | ||
| Bacteremic pneumonia | 41.3 | 18.4 |
| Bacteremia | 32.0 | 12.2 |
| Meningitis | 23.9 | 38.8 |
| Septic arthritis | 7.8 | 16.3 |
| Cellulitis | 4.4 | 12.2 |
| Epiglottitis | 3.9 | 0.0 |
| Other invasive disease | 0.5 | 2.1 |
| Hospitalized, % | 94.8 | 87.8 |
| Duration of hospitalization in days, median (range) | 7 (0–126) | 8 (0–68) |
| Died,c % | 7.8 | 10.2 |
| Characteristics . | United Statesa (N = 386) . | Alaska(N = 49) . |
|---|---|---|
| Age in years, median (range) | 30 (0–92) | 1 (0–77) |
| Sex, % | ||
| Male | 50.0 | 61.2 |
| Race, % | ||
| White | 59.3 | 4.1 |
| Black | 14.8 | 0.0 |
| AI/AN | 14.8 | 93.9 |
| Asian/PI | 1.3 | 2.0 |
| Unknown | 9.8 | 0.0 |
| Ethnicity, % | ||
| Hispanic/Latino | 15.0 | N/A |
| Non-Hispanic/Latino | 68.1 | N/A |
| Unknown | 16.8 | N/A |
| Clinical syndrome,b % | ||
| Bacteremic pneumonia | 41.3 | 18.4 |
| Bacteremia | 32.0 | 12.2 |
| Meningitis | 23.9 | 38.8 |
| Septic arthritis | 7.8 | 16.3 |
| Cellulitis | 4.4 | 12.2 |
| Epiglottitis | 3.9 | 0.0 |
| Other invasive disease | 0.5 | 2.1 |
| Hospitalized, % | 94.8 | 87.8 |
| Duration of hospitalization in days, median (range) | 7 (0–126) | 8 (0–68) |
| Died,c % | 7.8 | 10.2 |
Abbreviations: AI/AN, American Indian and Alaska Native; N/A, not available; PI, Pacific Islander.
aNote: data shown in this column are from Active Bacterial Core surveillance sites and do not include all cases in the United States.
bInformation on clinical syndrome was available for 385/386 (99.7%) cases in the United States and 49/49 (100%) cases in Alaska. Clinical syndrome was not mutually exclusive.
cInformation on outcome was available for 384/386 (99.5%) cases in the United States and 49/49 (100%) cases in Alaska.
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