Table 1.

Baseline patient characteristics and operative details

VariableStudy population (N = 1126)
Age (years)67.1 ± 12.1
Gender (male)820 (72.8)
Body mass index (kg/m2)30.1 ± 6.1
Body surface area (m2)2.1 ± 0.3
Diabetes335 (29.8)
Dialysis22 (2.0)
Lung disease274 (24.3)
COPD96 (8.5) 
Cerebrovascular disease164 (14.6)
Peripheral artery disease151 (13.4)
Prior myocardial infarction131 (11.6)
Heart failure168 (14.9)
Hypertension938 (83.3)
Dyslipidaemia841 (74.7)
Liver disease31 (2.8)
Family history of CAD223 (19.8)
Arrhythmia211 (18.7)
Atrial fibrillation188 (16.7)
Persistent/permanent87 (7.7)
Other atrial fibrillation 101 (9.0)
Smoking history (current/former)616 (54.7)
Illicit drug use56 (5.0)
Alcohol use (drinks/week)
None458 (40.7)
<2/week417 (37.0)
2–7/week159 (14.1)
>7/week92 (8.2)
Depression151 (13.4)
Endocarditis58 (5.1)
Mediastinal radiation18 (1.6)
Immunosuppression39 (3.5)
Cardiogenic shock28 (2.5)
Albumin3.7 ± 0.5
Ejection fraction (%)55.3 ± 13.2
Haemoglobin (g/dl)13.3 ± 2.1 
Platelets (x10^3/uL)214 ± 68
Degree of aortic insufficiency
None269 (23.9)
Trace148 (13.1)
Mild337 (29.9)
Moderate182 (16.2)
Severe190 (16.9)
Society of thoracic surgeons score0.03 ± 0.03
Redo operations114 (10.1)
Indication
Endocarditis58 (5.1)
Root/aorta operation88 (7.8)
Aortic stenosis765 (67.9)
Aortic insufficiency215 (19.1)
Operative status
Elective899 (79.8)
Urgent193 (17.1)
Emergent34 (3.0)
Operative approach
Sternotomy983 (87.3)
Mini-sternotomy127 (11.3)
Right thoracotomy16 (1.4)
Concomitant procedure
Coronary artery bypass grafting413 (36.7)
Mitral or tricuspid valve86 (7.6)
Antiarrhythmic procedure52 (4.6)
Root operation85 (7.6)
Cross clamp time (min)129.1 ± 58.4
Cardiopulmonary bypass time (min)161.5 ± 73.6
VariableStudy population (N = 1126)
Age (years)67.1 ± 12.1
Gender (male)820 (72.8)
Body mass index (kg/m2)30.1 ± 6.1
Body surface area (m2)2.1 ± 0.3
Diabetes335 (29.8)
Dialysis22 (2.0)
Lung disease274 (24.3)
COPD96 (8.5) 
Cerebrovascular disease164 (14.6)
Peripheral artery disease151 (13.4)
Prior myocardial infarction131 (11.6)
Heart failure168 (14.9)
Hypertension938 (83.3)
Dyslipidaemia841 (74.7)
Liver disease31 (2.8)
Family history of CAD223 (19.8)
Arrhythmia211 (18.7)
Atrial fibrillation188 (16.7)
Persistent/permanent87 (7.7)
Other atrial fibrillation 101 (9.0)
Smoking history (current/former)616 (54.7)
Illicit drug use56 (5.0)
Alcohol use (drinks/week)
None458 (40.7)
<2/week417 (37.0)
2–7/week159 (14.1)
>7/week92 (8.2)
Depression151 (13.4)
Endocarditis58 (5.1)
Mediastinal radiation18 (1.6)
Immunosuppression39 (3.5)
Cardiogenic shock28 (2.5)
Albumin3.7 ± 0.5
Ejection fraction (%)55.3 ± 13.2
Haemoglobin (g/dl)13.3 ± 2.1 
Platelets (x10^3/uL)214 ± 68
Degree of aortic insufficiency
None269 (23.9)
Trace148 (13.1)
Mild337 (29.9)
Moderate182 (16.2)
Severe190 (16.9)
Society of thoracic surgeons score0.03 ± 0.03
Redo operations114 (10.1)
Indication
Endocarditis58 (5.1)
Root/aorta operation88 (7.8)
Aortic stenosis765 (67.9)
Aortic insufficiency215 (19.1)
Operative status
Elective899 (79.8)
Urgent193 (17.1)
Emergent34 (3.0)
Operative approach
Sternotomy983 (87.3)
Mini-sternotomy127 (11.3)
Right thoracotomy16 (1.4)
Concomitant procedure
Coronary artery bypass grafting413 (36.7)
Mitral or tricuspid valve86 (7.6)
Antiarrhythmic procedure52 (4.6)
Root operation85 (7.6)
Cross clamp time (min)129.1 ± 58.4
Cardiopulmonary bypass time (min)161.5 ± 73.6

Continuous variables are presented as mean ± SD and categorical variables as number (%).

Table 1.

Baseline patient characteristics and operative details

VariableStudy population (N = 1126)
Age (years)67.1 ± 12.1
Gender (male)820 (72.8)
Body mass index (kg/m2)30.1 ± 6.1
Body surface area (m2)2.1 ± 0.3
Diabetes335 (29.8)
Dialysis22 (2.0)
Lung disease274 (24.3)
COPD96 (8.5) 
Cerebrovascular disease164 (14.6)
Peripheral artery disease151 (13.4)
Prior myocardial infarction131 (11.6)
Heart failure168 (14.9)
Hypertension938 (83.3)
Dyslipidaemia841 (74.7)
Liver disease31 (2.8)
Family history of CAD223 (19.8)
Arrhythmia211 (18.7)
Atrial fibrillation188 (16.7)
Persistent/permanent87 (7.7)
Other atrial fibrillation 101 (9.0)
Smoking history (current/former)616 (54.7)
Illicit drug use56 (5.0)
Alcohol use (drinks/week)
None458 (40.7)
<2/week417 (37.0)
2–7/week159 (14.1)
>7/week92 (8.2)
Depression151 (13.4)
Endocarditis58 (5.1)
Mediastinal radiation18 (1.6)
Immunosuppression39 (3.5)
Cardiogenic shock28 (2.5)
Albumin3.7 ± 0.5
Ejection fraction (%)55.3 ± 13.2
Haemoglobin (g/dl)13.3 ± 2.1 
Platelets (x10^3/uL)214 ± 68
Degree of aortic insufficiency
None269 (23.9)
Trace148 (13.1)
Mild337 (29.9)
Moderate182 (16.2)
Severe190 (16.9)
Society of thoracic surgeons score0.03 ± 0.03
Redo operations114 (10.1)
Indication
Endocarditis58 (5.1)
Root/aorta operation88 (7.8)
Aortic stenosis765 (67.9)
Aortic insufficiency215 (19.1)
Operative status
Elective899 (79.8)
Urgent193 (17.1)
Emergent34 (3.0)
Operative approach
Sternotomy983 (87.3)
Mini-sternotomy127 (11.3)
Right thoracotomy16 (1.4)
Concomitant procedure
Coronary artery bypass grafting413 (36.7)
Mitral or tricuspid valve86 (7.6)
Antiarrhythmic procedure52 (4.6)
Root operation85 (7.6)
Cross clamp time (min)129.1 ± 58.4
Cardiopulmonary bypass time (min)161.5 ± 73.6
VariableStudy population (N = 1126)
Age (years)67.1 ± 12.1
Gender (male)820 (72.8)
Body mass index (kg/m2)30.1 ± 6.1
Body surface area (m2)2.1 ± 0.3
Diabetes335 (29.8)
Dialysis22 (2.0)
Lung disease274 (24.3)
COPD96 (8.5) 
Cerebrovascular disease164 (14.6)
Peripheral artery disease151 (13.4)
Prior myocardial infarction131 (11.6)
Heart failure168 (14.9)
Hypertension938 (83.3)
Dyslipidaemia841 (74.7)
Liver disease31 (2.8)
Family history of CAD223 (19.8)
Arrhythmia211 (18.7)
Atrial fibrillation188 (16.7)
Persistent/permanent87 (7.7)
Other atrial fibrillation 101 (9.0)
Smoking history (current/former)616 (54.7)
Illicit drug use56 (5.0)
Alcohol use (drinks/week)
None458 (40.7)
<2/week417 (37.0)
2–7/week159 (14.1)
>7/week92 (8.2)
Depression151 (13.4)
Endocarditis58 (5.1)
Mediastinal radiation18 (1.6)
Immunosuppression39 (3.5)
Cardiogenic shock28 (2.5)
Albumin3.7 ± 0.5
Ejection fraction (%)55.3 ± 13.2
Haemoglobin (g/dl)13.3 ± 2.1 
Platelets (x10^3/uL)214 ± 68
Degree of aortic insufficiency
None269 (23.9)
Trace148 (13.1)
Mild337 (29.9)
Moderate182 (16.2)
Severe190 (16.9)
Society of thoracic surgeons score0.03 ± 0.03
Redo operations114 (10.1)
Indication
Endocarditis58 (5.1)
Root/aorta operation88 (7.8)
Aortic stenosis765 (67.9)
Aortic insufficiency215 (19.1)
Operative status
Elective899 (79.8)
Urgent193 (17.1)
Emergent34 (3.0)
Operative approach
Sternotomy983 (87.3)
Mini-sternotomy127 (11.3)
Right thoracotomy16 (1.4)
Concomitant procedure
Coronary artery bypass grafting413 (36.7)
Mitral or tricuspid valve86 (7.6)
Antiarrhythmic procedure52 (4.6)
Root operation85 (7.6)
Cross clamp time (min)129.1 ± 58.4
Cardiopulmonary bypass time (min)161.5 ± 73.6

Continuous variables are presented as mean ± SD and categorical variables as number (%).

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