Table 2
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Phenotypic and genetic correlations for maternal vs. paternal lifespan and age vs. lifespan. N- Overlap is the number of samples which have phenotypes measured for both traits. N - SNPs is the number of variants used in LD Score regression analysis. Phenotypic variance (PVAR), the slope of the correlation (beta), and the Pearson correlation coefficient (rp). Genetic heritability (h2g) and genetic correlation (rg)
TraitsPhenotypic CorrelationGenetic Correlation
LifespanLifespanN - OverlapPVAR Mat.PVAR Pat.rpN - SNPs%h2g Maternal (SE)%h2g Paternal (SE)rg (SE)
Maternal_1918Paternal_1918112498161.53166.200.0683854943.66 (0.64)7.54 (0.58)0.651 (0.090)
Maternal_1940Paternal_1940219514153.42160.270.0953867245.34 (0.36)7.62 (0.32)0.937 (0.041)
AgeLifespanN - OverlapPVAR AgePVAR LifespanrpN - SNPs%h2g Age (SE)%h2g Lifespan (SE)rg (SE)
MaleMaternal9049662.03153.940.0953859743.04 (0.42)4.78 (0.92)0.700 (0.127)
MalePaternal9831359.88162.090.0003860862.68 (0.37)7.04 (0.86)0.432 (0.097)
FemaleMaternal10957166.67153.840.0983862093.69 (0.44)4.88 (0.76)0.693 (0.094)
FemalePaternal11580659.86161.660.0043862932.61 (0.40)7.54 (0.80)0.527 (0.094)
TraitsPhenotypic CorrelationGenetic Correlation
LifespanLifespanN - OverlapPVAR Mat.PVAR Pat.rpN - SNPs%h2g Maternal (SE)%h2g Paternal (SE)rg (SE)
Maternal_1918Paternal_1918112498161.53166.200.0683854943.66 (0.64)7.54 (0.58)0.651 (0.090)
Maternal_1940Paternal_1940219514153.42160.270.0953867245.34 (0.36)7.62 (0.32)0.937 (0.041)
AgeLifespanN - OverlapPVAR AgePVAR LifespanrpN - SNPs%h2g Age (SE)%h2g Lifespan (SE)rg (SE)
MaleMaternal9049662.03153.940.0953859743.04 (0.42)4.78 (0.92)0.700 (0.127)
MalePaternal9831359.88162.090.0003860862.68 (0.37)7.04 (0.86)0.432 (0.097)
FemaleMaternal10957166.67153.840.0983862093.69 (0.44)4.88 (0.76)0.693 (0.094)
FemalePaternal11580659.86161.660.0043862932.61 (0.40)7.54 (0.80)0.527 (0.094)
Table 2
Open in new tab
Phenotypic and genetic correlations for maternal vs. paternal lifespan and age vs. lifespan. N- Overlap is the number of samples which have phenotypes measured for both traits. N - SNPs is the number of variants used in LD Score regression analysis. Phenotypic variance (PVAR), the slope of the correlation (beta), and the Pearson correlation coefficient (rp). Genetic heritability (h2g) and genetic correlation (rg)
TraitsPhenotypic CorrelationGenetic Correlation
LifespanLifespanN - OverlapPVAR Mat.PVAR Pat.rpN - SNPs%h2g Maternal (SE)%h2g Paternal (SE)rg (SE)
Maternal_1918Paternal_1918112498161.53166.200.0683854943.66 (0.64)7.54 (0.58)0.651 (0.090)
Maternal_1940Paternal_1940219514153.42160.270.0953867245.34 (0.36)7.62 (0.32)0.937 (0.041)
AgeLifespanN - OverlapPVAR AgePVAR LifespanrpN - SNPs%h2g Age (SE)%h2g Lifespan (SE)rg (SE)
MaleMaternal9049662.03153.940.0953859743.04 (0.42)4.78 (0.92)0.700 (0.127)
MalePaternal9831359.88162.090.0003860862.68 (0.37)7.04 (0.86)0.432 (0.097)
FemaleMaternal10957166.67153.840.0983862093.69 (0.44)4.88 (0.76)0.693 (0.094)
FemalePaternal11580659.86161.660.0043862932.61 (0.40)7.54 (0.80)0.527 (0.094)
TraitsPhenotypic CorrelationGenetic Correlation
LifespanLifespanN - OverlapPVAR Mat.PVAR Pat.rpN - SNPs%h2g Maternal (SE)%h2g Paternal (SE)rg (SE)
Maternal_1918Paternal_1918112498161.53166.200.0683854943.66 (0.64)7.54 (0.58)0.651 (0.090)
Maternal_1940Paternal_1940219514153.42160.270.0953867245.34 (0.36)7.62 (0.32)0.937 (0.041)
AgeLifespanN - OverlapPVAR AgePVAR LifespanrpN - SNPs%h2g Age (SE)%h2g Lifespan (SE)rg (SE)
MaleMaternal9049662.03153.940.0953859743.04 (0.42)4.78 (0.92)0.700 (0.127)
MalePaternal9831359.88162.090.0003860862.68 (0.37)7.04 (0.86)0.432 (0.097)
FemaleMaternal10957166.67153.840.0983862093.69 (0.44)4.88 (0.76)0.693 (0.094)
FemalePaternal11580659.86161.660.0043862932.61 (0.40)7.54 (0.80)0.527 (0.094)
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