Table 1.

Message content and structure for the txt2protect intervention and control conditions

InterventionControl
Phase 1: Week 1Information: the basicsHIV/STI facts
• Basic information about HIV and STIs
• Details about HPV vaccination (safety, efficacy, and dosing)
• Vaccine recommendation from study team physician
• Details about how and where to get the first dose
Constructs: Knowledge, Attitudes, Susceptibility, Severity
• Basic information about HIV and STIs
• Prevalence, transmission, symptoms, health consequences, and current treatments
Sample message“This program has been designed to help you prevent HPV infection and its health consequences. Tomorrow we’ll talk about steps you can take to protect yourself.”“Although there are many STIs we could review, we’re going to focus on the five most common STIs: HPV, chlamydia, gonorrhea, genital herpes, and syphilis.”
Phase 1: Week 2Motivation: overcoming barriersPrevention and testing
• Overcoming common perceived barriers (HPV-related misinformation and lack of provider recommendation)
• Norms for HPV vaccination
• Reasons young MSM have decided to get vaccinated
Constructs: Attitudes, Norms, Susceptibility, Regret
• Using condoms correctly and overcoming barriers
• Vaccines to prevent STIs (Hepatitis A and B and HPV)
• Pre-exposure prophylaxis (PrEP)
• STI and HIV testing
Sample message“The next two days we’ll review reasons some young men haven’t received the HPV vaccine and ways to overcome those barriers.”“To wrap up Week 2, let’s talk about STI and HIV testing. Getting tested for STIs and HIV is an essential step for maintaining sexual health.”
Phase 1: Week 3Behavioral skills: next stepsHealthy relationships
• Vaccine cost and health insurance issues
• List of clinics offering HPV vaccine, search tool for local pharmacies (Health Map Vaccine Finder) [50]
• Talking with a provider/parent about the HPV vaccine or one’s sexual identity
• Action plan for getting vaccinated [51]
Constructs: Perceived behavioral control, Self-efficacy
• Tips for good communication
• Signs of an unhealthy relationship
• Meeting both partners’ health, emotional, and sexual needs
Sample message“Last week we mentioned you might need to advocate for your own health if a doctor doesn’t raise the issue. So, how can you bring up the HPV vaccine to a doctor?”“A healthy relationship is one that meets both partners’ health, emotional, and sexual needs. What this means may change over time as you grow as a person.”
Phase 2Reinforced Phase 1 content to encourage continued program engagement via “booster” messages
Sample message“If you’ve been wanting to get vaccinated but are having trouble finding the time, consider a walk-in clinic or pharmacy.”“Taking PrEP daily can reduce risk of getting HIV from sex by more than 90%. Using both PrEP and condoms can provide even greater protection.”
InterventionControl
Phase 1: Week 1Information: the basicsHIV/STI facts
• Basic information about HIV and STIs
• Details about HPV vaccination (safety, efficacy, and dosing)
• Vaccine recommendation from study team physician
• Details about how and where to get the first dose
Constructs: Knowledge, Attitudes, Susceptibility, Severity
• Basic information about HIV and STIs
• Prevalence, transmission, symptoms, health consequences, and current treatments
Sample message“This program has been designed to help you prevent HPV infection and its health consequences. Tomorrow we’ll talk about steps you can take to protect yourself.”“Although there are many STIs we could review, we’re going to focus on the five most common STIs: HPV, chlamydia, gonorrhea, genital herpes, and syphilis.”
Phase 1: Week 2Motivation: overcoming barriersPrevention and testing
• Overcoming common perceived barriers (HPV-related misinformation and lack of provider recommendation)
• Norms for HPV vaccination
• Reasons young MSM have decided to get vaccinated
Constructs: Attitudes, Norms, Susceptibility, Regret
• Using condoms correctly and overcoming barriers
• Vaccines to prevent STIs (Hepatitis A and B and HPV)
• Pre-exposure prophylaxis (PrEP)
• STI and HIV testing
Sample message“The next two days we’ll review reasons some young men haven’t received the HPV vaccine and ways to overcome those barriers.”“To wrap up Week 2, let’s talk about STI and HIV testing. Getting tested for STIs and HIV is an essential step for maintaining sexual health.”
Phase 1: Week 3Behavioral skills: next stepsHealthy relationships
• Vaccine cost and health insurance issues
• List of clinics offering HPV vaccine, search tool for local pharmacies (Health Map Vaccine Finder) [50]
• Talking with a provider/parent about the HPV vaccine or one’s sexual identity
• Action plan for getting vaccinated [51]
Constructs: Perceived behavioral control, Self-efficacy
• Tips for good communication
• Signs of an unhealthy relationship
• Meeting both partners’ health, emotional, and sexual needs
Sample message“Last week we mentioned you might need to advocate for your own health if a doctor doesn’t raise the issue. So, how can you bring up the HPV vaccine to a doctor?”“A healthy relationship is one that meets both partners’ health, emotional, and sexual needs. What this means may change over time as you grow as a person.”
Phase 2Reinforced Phase 1 content to encourage continued program engagement via “booster” messages
Sample message“If you’ve been wanting to get vaccinated but are having trouble finding the time, consider a walk-in clinic or pharmacy.”“Taking PrEP daily can reduce risk of getting HIV from sex by more than 90%. Using both PrEP and condoms can provide even greater protection.”

HPV human papillomavirus; MSM men who have sex with men; STI sexually transmitted infection.

Table 1.

Message content and structure for the txt2protect intervention and control conditions

InterventionControl
Phase 1: Week 1Information: the basicsHIV/STI facts
• Basic information about HIV and STIs
• Details about HPV vaccination (safety, efficacy, and dosing)
• Vaccine recommendation from study team physician
• Details about how and where to get the first dose
Constructs: Knowledge, Attitudes, Susceptibility, Severity
• Basic information about HIV and STIs
• Prevalence, transmission, symptoms, health consequences, and current treatments
Sample message“This program has been designed to help you prevent HPV infection and its health consequences. Tomorrow we’ll talk about steps you can take to protect yourself.”“Although there are many STIs we could review, we’re going to focus on the five most common STIs: HPV, chlamydia, gonorrhea, genital herpes, and syphilis.”
Phase 1: Week 2Motivation: overcoming barriersPrevention and testing
• Overcoming common perceived barriers (HPV-related misinformation and lack of provider recommendation)
• Norms for HPV vaccination
• Reasons young MSM have decided to get vaccinated
Constructs: Attitudes, Norms, Susceptibility, Regret
• Using condoms correctly and overcoming barriers
• Vaccines to prevent STIs (Hepatitis A and B and HPV)
• Pre-exposure prophylaxis (PrEP)
• STI and HIV testing
Sample message“The next two days we’ll review reasons some young men haven’t received the HPV vaccine and ways to overcome those barriers.”“To wrap up Week 2, let’s talk about STI and HIV testing. Getting tested for STIs and HIV is an essential step for maintaining sexual health.”
Phase 1: Week 3Behavioral skills: next stepsHealthy relationships
• Vaccine cost and health insurance issues
• List of clinics offering HPV vaccine, search tool for local pharmacies (Health Map Vaccine Finder) [50]
• Talking with a provider/parent about the HPV vaccine or one’s sexual identity
• Action plan for getting vaccinated [51]
Constructs: Perceived behavioral control, Self-efficacy
• Tips for good communication
• Signs of an unhealthy relationship
• Meeting both partners’ health, emotional, and sexual needs
Sample message“Last week we mentioned you might need to advocate for your own health if a doctor doesn’t raise the issue. So, how can you bring up the HPV vaccine to a doctor?”“A healthy relationship is one that meets both partners’ health, emotional, and sexual needs. What this means may change over time as you grow as a person.”
Phase 2Reinforced Phase 1 content to encourage continued program engagement via “booster” messages
Sample message“If you’ve been wanting to get vaccinated but are having trouble finding the time, consider a walk-in clinic or pharmacy.”“Taking PrEP daily can reduce risk of getting HIV from sex by more than 90%. Using both PrEP and condoms can provide even greater protection.”
InterventionControl
Phase 1: Week 1Information: the basicsHIV/STI facts
• Basic information about HIV and STIs
• Details about HPV vaccination (safety, efficacy, and dosing)
• Vaccine recommendation from study team physician
• Details about how and where to get the first dose
Constructs: Knowledge, Attitudes, Susceptibility, Severity
• Basic information about HIV and STIs
• Prevalence, transmission, symptoms, health consequences, and current treatments
Sample message“This program has been designed to help you prevent HPV infection and its health consequences. Tomorrow we’ll talk about steps you can take to protect yourself.”“Although there are many STIs we could review, we’re going to focus on the five most common STIs: HPV, chlamydia, gonorrhea, genital herpes, and syphilis.”
Phase 1: Week 2Motivation: overcoming barriersPrevention and testing
• Overcoming common perceived barriers (HPV-related misinformation and lack of provider recommendation)
• Norms for HPV vaccination
• Reasons young MSM have decided to get vaccinated
Constructs: Attitudes, Norms, Susceptibility, Regret
• Using condoms correctly and overcoming barriers
• Vaccines to prevent STIs (Hepatitis A and B and HPV)
• Pre-exposure prophylaxis (PrEP)
• STI and HIV testing
Sample message“The next two days we’ll review reasons some young men haven’t received the HPV vaccine and ways to overcome those barriers.”“To wrap up Week 2, let’s talk about STI and HIV testing. Getting tested for STIs and HIV is an essential step for maintaining sexual health.”
Phase 1: Week 3Behavioral skills: next stepsHealthy relationships
• Vaccine cost and health insurance issues
• List of clinics offering HPV vaccine, search tool for local pharmacies (Health Map Vaccine Finder) [50]
• Talking with a provider/parent about the HPV vaccine or one’s sexual identity
• Action plan for getting vaccinated [51]
Constructs: Perceived behavioral control, Self-efficacy
• Tips for good communication
• Signs of an unhealthy relationship
• Meeting both partners’ health, emotional, and sexual needs
Sample message“Last week we mentioned you might need to advocate for your own health if a doctor doesn’t raise the issue. So, how can you bring up the HPV vaccine to a doctor?”“A healthy relationship is one that meets both partners’ health, emotional, and sexual needs. What this means may change over time as you grow as a person.”
Phase 2Reinforced Phase 1 content to encourage continued program engagement via “booster” messages
Sample message“If you’ve been wanting to get vaccinated but are having trouble finding the time, consider a walk-in clinic or pharmacy.”“Taking PrEP daily can reduce risk of getting HIV from sex by more than 90%. Using both PrEP and condoms can provide even greater protection.”

HPV human papillomavirus; MSM men who have sex with men; STI sexually transmitted infection.

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