| . | MSA-C (n = 25) . | MSA-P (n = 24) . | P value . |
|---|---|---|---|
| Male sex, n (%) | 20 (80.0) | 13 (54.1) | 0.054 |
| Age at disease onset, y | 57.6 ± 6.7 | 59.7 ± 11.2 | 0.483 |
| Age at stridor onset, y | 60.1 ± 7.1 | 63.1 ± 11.7 | 0.335 |
| Stridor as the first manifestation of the disease, n (%) | 1 (4.0) | 3 (12.5) | 0.257 |
| Age at V-PSG, y | 61.5 ± 6.9 | 63.2 ± 10.8 | 0.555 |
| Inspiratory stridor, n (%) | 25 (100) | 22 (91.7) | 0.141 |
| Expiratory stridor, n (%) | 2 (8.0) | 2 (8.3) | 1.000 |
| Inspiratory and expiratory stridor, n (%) | 2 (8.0) | 0 (0) | 0.149 |
| AHI, n | 16.8 ± 17.0 | 20.9 ± 19.9 | 0.472 |
| AHI > 5, n (%) | 19 (76.0) | 21 (87.5) | 0.480 |
| AHI > 10, n (%) | 11 (44.0) | 17 (70.8) | 0.087 |
| AHI > 30, n (%) | 4 (16.0) | 4 (16.6) | 1.000 |
| Obstructive apnea index, n | 16.2 ± 16.8 | 20.7 ± 19.8 | 0.383 |
| Central apnea index, n | 0.5 ± 1.2 | 0.2 ± 0.7 | 0.850 |
| CT90, n | 13.0 ± 21.8 | 15.4 ± 22.9 | 0.780 |
| Nadir O2Hb, n | 84.2 ± 8.1 | 83.2 ± 7.1 | 0.580 |
| Stridor during wakefulness, n (%) | 0 (0) | 7 (29.2) | 0.004 |
| Laryngoscopy, n (%) | 23 (92.0) | 19 (79.2) | 0.199 |
| Abnormal vocal cord mobility in laryngoscopy, n (%) | 21 (91.3) | 18 (95.0) | 0.667 |
| Vocal cord bilateral impairment, n (%) | 13 (61.9) | 14 (77.8) | 0.284 |
| Vocal cord unilateral impairment, n (%) | 8 (38.1) | 4 (22.2) | 0.284 |
| Vocal cord flickering, n (%) | 3 (14.3) | 1 (5.5) | 0.393 |
| CPAP therapy, n (%) | 23 (92.0) | 19 (79.1) | 0.123 |
| CPAP pressure, cmH2O | 8.7 ± 2.3 | 7.9 ± 2.4 | 0.255 |
| Tracheostomy, n (%) | 5 (20.0) | 8 (33.3) | 0.291 |
| . | MSA-C (n = 25) . | MSA-P (n = 24) . | P value . |
|---|---|---|---|
| Male sex, n (%) | 20 (80.0) | 13 (54.1) | 0.054 |
| Age at disease onset, y | 57.6 ± 6.7 | 59.7 ± 11.2 | 0.483 |
| Age at stridor onset, y | 60.1 ± 7.1 | 63.1 ± 11.7 | 0.335 |
| Stridor as the first manifestation of the disease, n (%) | 1 (4.0) | 3 (12.5) | 0.257 |
| Age at V-PSG, y | 61.5 ± 6.9 | 63.2 ± 10.8 | 0.555 |
| Inspiratory stridor, n (%) | 25 (100) | 22 (91.7) | 0.141 |
| Expiratory stridor, n (%) | 2 (8.0) | 2 (8.3) | 1.000 |
| Inspiratory and expiratory stridor, n (%) | 2 (8.0) | 0 (0) | 0.149 |
| AHI, n | 16.8 ± 17.0 | 20.9 ± 19.9 | 0.472 |
| AHI > 5, n (%) | 19 (76.0) | 21 (87.5) | 0.480 |
| AHI > 10, n (%) | 11 (44.0) | 17 (70.8) | 0.087 |
| AHI > 30, n (%) | 4 (16.0) | 4 (16.6) | 1.000 |
| Obstructive apnea index, n | 16.2 ± 16.8 | 20.7 ± 19.8 | 0.383 |
| Central apnea index, n | 0.5 ± 1.2 | 0.2 ± 0.7 | 0.850 |
| CT90, n | 13.0 ± 21.8 | 15.4 ± 22.9 | 0.780 |
| Nadir O2Hb, n | 84.2 ± 8.1 | 83.2 ± 7.1 | 0.580 |
| Stridor during wakefulness, n (%) | 0 (0) | 7 (29.2) | 0.004 |
| Laryngoscopy, n (%) | 23 (92.0) | 19 (79.2) | 0.199 |
| Abnormal vocal cord mobility in laryngoscopy, n (%) | 21 (91.3) | 18 (95.0) | 0.667 |
| Vocal cord bilateral impairment, n (%) | 13 (61.9) | 14 (77.8) | 0.284 |
| Vocal cord unilateral impairment, n (%) | 8 (38.1) | 4 (22.2) | 0.284 |
| Vocal cord flickering, n (%) | 3 (14.3) | 1 (5.5) | 0.393 |
| CPAP therapy, n (%) | 23 (92.0) | 19 (79.1) | 0.123 |
| CPAP pressure, cmH2O | 8.7 ± 2.3 | 7.9 ± 2.4 | 0.255 |
| Tracheostomy, n (%) | 5 (20.0) | 8 (33.3) | 0.291 |
Values are expressed as mean, standard deviation, number, and percentatges. MSA, multiple system atrophy; MSA-C, cerebellar subtype of multiple system atrophy; MSA-P, parkinsonian subtype of múltiple system atrophy; V-PSG, video-polysomnography; AHI, apnea–hypopnea index; CT90, cummulative percentatge of total sleep time with oxyhemoglobin saturation below 90; O2Hb, oxyhemoglobin saturation; CPAP, continuous positive airway pressure.
| . | MSA-C (n = 25) . | MSA-P (n = 24) . | P value . |
|---|---|---|---|
| Male sex, n (%) | 20 (80.0) | 13 (54.1) | 0.054 |
| Age at disease onset, y | 57.6 ± 6.7 | 59.7 ± 11.2 | 0.483 |
| Age at stridor onset, y | 60.1 ± 7.1 | 63.1 ± 11.7 | 0.335 |
| Stridor as the first manifestation of the disease, n (%) | 1 (4.0) | 3 (12.5) | 0.257 |
| Age at V-PSG, y | 61.5 ± 6.9 | 63.2 ± 10.8 | 0.555 |
| Inspiratory stridor, n (%) | 25 (100) | 22 (91.7) | 0.141 |
| Expiratory stridor, n (%) | 2 (8.0) | 2 (8.3) | 1.000 |
| Inspiratory and expiratory stridor, n (%) | 2 (8.0) | 0 (0) | 0.149 |
| AHI, n | 16.8 ± 17.0 | 20.9 ± 19.9 | 0.472 |
| AHI > 5, n (%) | 19 (76.0) | 21 (87.5) | 0.480 |
| AHI > 10, n (%) | 11 (44.0) | 17 (70.8) | 0.087 |
| AHI > 30, n (%) | 4 (16.0) | 4 (16.6) | 1.000 |
| Obstructive apnea index, n | 16.2 ± 16.8 | 20.7 ± 19.8 | 0.383 |
| Central apnea index, n | 0.5 ± 1.2 | 0.2 ± 0.7 | 0.850 |
| CT90, n | 13.0 ± 21.8 | 15.4 ± 22.9 | 0.780 |
| Nadir O2Hb, n | 84.2 ± 8.1 | 83.2 ± 7.1 | 0.580 |
| Stridor during wakefulness, n (%) | 0 (0) | 7 (29.2) | 0.004 |
| Laryngoscopy, n (%) | 23 (92.0) | 19 (79.2) | 0.199 |
| Abnormal vocal cord mobility in laryngoscopy, n (%) | 21 (91.3) | 18 (95.0) | 0.667 |
| Vocal cord bilateral impairment, n (%) | 13 (61.9) | 14 (77.8) | 0.284 |
| Vocal cord unilateral impairment, n (%) | 8 (38.1) | 4 (22.2) | 0.284 |
| Vocal cord flickering, n (%) | 3 (14.3) | 1 (5.5) | 0.393 |
| CPAP therapy, n (%) | 23 (92.0) | 19 (79.1) | 0.123 |
| CPAP pressure, cmH2O | 8.7 ± 2.3 | 7.9 ± 2.4 | 0.255 |
| Tracheostomy, n (%) | 5 (20.0) | 8 (33.3) | 0.291 |
| . | MSA-C (n = 25) . | MSA-P (n = 24) . | P value . |
|---|---|---|---|
| Male sex, n (%) | 20 (80.0) | 13 (54.1) | 0.054 |
| Age at disease onset, y | 57.6 ± 6.7 | 59.7 ± 11.2 | 0.483 |
| Age at stridor onset, y | 60.1 ± 7.1 | 63.1 ± 11.7 | 0.335 |
| Stridor as the first manifestation of the disease, n (%) | 1 (4.0) | 3 (12.5) | 0.257 |
| Age at V-PSG, y | 61.5 ± 6.9 | 63.2 ± 10.8 | 0.555 |
| Inspiratory stridor, n (%) | 25 (100) | 22 (91.7) | 0.141 |
| Expiratory stridor, n (%) | 2 (8.0) | 2 (8.3) | 1.000 |
| Inspiratory and expiratory stridor, n (%) | 2 (8.0) | 0 (0) | 0.149 |
| AHI, n | 16.8 ± 17.0 | 20.9 ± 19.9 | 0.472 |
| AHI > 5, n (%) | 19 (76.0) | 21 (87.5) | 0.480 |
| AHI > 10, n (%) | 11 (44.0) | 17 (70.8) | 0.087 |
| AHI > 30, n (%) | 4 (16.0) | 4 (16.6) | 1.000 |
| Obstructive apnea index, n | 16.2 ± 16.8 | 20.7 ± 19.8 | 0.383 |
| Central apnea index, n | 0.5 ± 1.2 | 0.2 ± 0.7 | 0.850 |
| CT90, n | 13.0 ± 21.8 | 15.4 ± 22.9 | 0.780 |
| Nadir O2Hb, n | 84.2 ± 8.1 | 83.2 ± 7.1 | 0.580 |
| Stridor during wakefulness, n (%) | 0 (0) | 7 (29.2) | 0.004 |
| Laryngoscopy, n (%) | 23 (92.0) | 19 (79.2) | 0.199 |
| Abnormal vocal cord mobility in laryngoscopy, n (%) | 21 (91.3) | 18 (95.0) | 0.667 |
| Vocal cord bilateral impairment, n (%) | 13 (61.9) | 14 (77.8) | 0.284 |
| Vocal cord unilateral impairment, n (%) | 8 (38.1) | 4 (22.2) | 0.284 |
| Vocal cord flickering, n (%) | 3 (14.3) | 1 (5.5) | 0.393 |
| CPAP therapy, n (%) | 23 (92.0) | 19 (79.1) | 0.123 |
| CPAP pressure, cmH2O | 8.7 ± 2.3 | 7.9 ± 2.4 | 0.255 |
| Tracheostomy, n (%) | 5 (20.0) | 8 (33.3) | 0.291 |
Values are expressed as mean, standard deviation, number, and percentatges. MSA, multiple system atrophy; MSA-C, cerebellar subtype of multiple system atrophy; MSA-P, parkinsonian subtype of múltiple system atrophy; V-PSG, video-polysomnography; AHI, apnea–hypopnea index; CT90, cummulative percentatge of total sleep time with oxyhemoglobin saturation below 90; O2Hb, oxyhemoglobin saturation; CPAP, continuous positive airway pressure.
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