Table 3.
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Hepcidin expression in mouse liver, kidney and plasma under control conditions and 18 h following RBT-3 administration

GroupHepatic
HAMP1 mRNA		Kidney HAMP1
mRNA		Plasma
hepcidin
(ng/mL)		Hepatic
hepcidin
(ng/mg protein)		Kidney hepcidin
(ng/mg protein)
Control (n = 5)27 ± 40.9 ± 0.2359 ± 532.0 ± 0.31.4 ± 0.1
24 h post-RBT-3 (n = 5)46 ± 6578 ± 1981057 ± 1786.2 ± 0.46.6 ± 1.5
P-value0.0280.01<0.001<0.001<0.005
GroupHepatic
HAMP1 mRNA		Kidney HAMP1
mRNA		Plasma
hepcidin
(ng/mL)		Hepatic
hepcidin
(ng/mg protein)		Kidney hepcidin
(ng/mg protein)
Control (n = 5)27 ± 40.9 ± 0.2359 ± 532.0 ± 0.31.4 ± 0.1
24 h post-RBT-3 (n = 5)46 ± 6578 ± 1981057 ± 1786.2 ± 0.46.6 ± 1.5
P-value0.0280.01<0.001<0.001<0.005

The HAMP1 mRNAs are factored by GAPDH. The values are mean ± SEM. P-values were derived by unpaired Student’s t-test.

Table 3.
Open in new tab

Hepcidin expression in mouse liver, kidney and plasma under control conditions and 18 h following RBT-3 administration

GroupHepatic
HAMP1 mRNA		Kidney HAMP1
mRNA		Plasma
hepcidin
(ng/mL)		Hepatic
hepcidin
(ng/mg protein)		Kidney hepcidin
(ng/mg protein)
Control (n = 5)27 ± 40.9 ± 0.2359 ± 532.0 ± 0.31.4 ± 0.1
24 h post-RBT-3 (n = 5)46 ± 6578 ± 1981057 ± 1786.2 ± 0.46.6 ± 1.5
P-value0.0280.01<0.001<0.001<0.005
GroupHepatic
HAMP1 mRNA		Kidney HAMP1
mRNA		Plasma
hepcidin
(ng/mL)		Hepatic
hepcidin
(ng/mg protein)		Kidney hepcidin
(ng/mg protein)
Control (n = 5)27 ± 40.9 ± 0.2359 ± 532.0 ± 0.31.4 ± 0.1
24 h post-RBT-3 (n = 5)46 ± 6578 ± 1981057 ± 1786.2 ± 0.46.6 ± 1.5
P-value0.0280.01<0.001<0.001<0.005

The HAMP1 mRNAs are factored by GAPDH. The values are mean ± SEM. P-values were derived by unpaired Student’s t-test.

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