| Disease Category . | Respiratory Support Requirement . | Management . |
|---|---|---|
| Mild/ moderate | No new or increased supplemental oxygen requirement | Supportive care |
| Severe | New or increase from baseline supplemental oxygen requirement without need for new or increase in baseline noninvasive/invasive mechanical ventilationa | Supportive care alone is appropriate for the majority of children. Use of potentially active antivirals could be considered on a case-by-case basis,b preferably as part of a clinical trial if available. |
| Critical | New or increased requirement for invasive or noninvasive mechanical ventilation,a sepsis, or multiorgan failure; or rapidly worsening clinical trajectory that does not yet meet these criteria | Supportive care may be appropriate for children who are severely ill with coronavirus disease 2019. Use of potentially active antivirals should be considered, preferably as part of a clinical trial if available. |
| Disease Category . | Respiratory Support Requirement . | Management . |
|---|---|---|
| Mild/ moderate | No new or increased supplemental oxygen requirement | Supportive care |
| Severe | New or increase from baseline supplemental oxygen requirement without need for new or increase in baseline noninvasive/invasive mechanical ventilationa | Supportive care alone is appropriate for the majority of children. Use of potentially active antivirals could be considered on a case-by-case basis,b preferably as part of a clinical trial if available. |
| Critical | New or increased requirement for invasive or noninvasive mechanical ventilation,a sepsis, or multiorgan failure; or rapidly worsening clinical trajectory that does not yet meet these criteria | Supportive care may be appropriate for children who are severely ill with coronavirus disease 2019. Use of potentially active antivirals should be considered, preferably as part of a clinical trial if available. |
aNoninvasive mechanical ventilation includes high-flow nasal canula, continuous positive airway pressure, or bilevel positive airway pressure.
bCase-by-case considerations could include underlying medical conditions and health status that may confer risk for more serious illness.
| Disease Category . | Respiratory Support Requirement . | Management . |
|---|---|---|
| Mild/ moderate | No new or increased supplemental oxygen requirement | Supportive care |
| Severe | New or increase from baseline supplemental oxygen requirement without need for new or increase in baseline noninvasive/invasive mechanical ventilationa | Supportive care alone is appropriate for the majority of children. Use of potentially active antivirals could be considered on a case-by-case basis,b preferably as part of a clinical trial if available. |
| Critical | New or increased requirement for invasive or noninvasive mechanical ventilation,a sepsis, or multiorgan failure; or rapidly worsening clinical trajectory that does not yet meet these criteria | Supportive care may be appropriate for children who are severely ill with coronavirus disease 2019. Use of potentially active antivirals should be considered, preferably as part of a clinical trial if available. |
| Disease Category . | Respiratory Support Requirement . | Management . |
|---|---|---|
| Mild/ moderate | No new or increased supplemental oxygen requirement | Supportive care |
| Severe | New or increase from baseline supplemental oxygen requirement without need for new or increase in baseline noninvasive/invasive mechanical ventilationa | Supportive care alone is appropriate for the majority of children. Use of potentially active antivirals could be considered on a case-by-case basis,b preferably as part of a clinical trial if available. |
| Critical | New or increased requirement for invasive or noninvasive mechanical ventilation,a sepsis, or multiorgan failure; or rapidly worsening clinical trajectory that does not yet meet these criteria | Supportive care may be appropriate for children who are severely ill with coronavirus disease 2019. Use of potentially active antivirals should be considered, preferably as part of a clinical trial if available. |
aNoninvasive mechanical ventilation includes high-flow nasal canula, continuous positive airway pressure, or bilevel positive airway pressure.
bCase-by-case considerations could include underlying medical conditions and health status that may confer risk for more serious illness.
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