| . | . | Agreement between continuous alternative ASDAS formulae with original-ASDAS (N = 823 patients, 2647 observations) . | Agreement between alternative ASDAS formulae with original-ASDAS-defined states of disease activity (N = 823 patients, 2647 observations) . |
|---|---|---|---|
| . | Mean difference with original-ASDAS . | ICC (95% CI) . | Weighted kappa (95% CI) . |
| ASDAS-Q1 | 0.12 | 0.97 (0.94, 0.98) | 0.86 (0.85, 0.87) |
| ASDAS-Q2 | 0.08 | 0.98 (0.97, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q14 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q23 | 0.12 | 0.98 (0.95, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q26 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q145 | 0.07 | 0.98 (0.97, 0.99) | 0.89 (0.88, 0.90) |
| ASDAS-Q236 | 0.10 | 0.98 (0.96, 0.99) | 0.89 (0.88, 0.89) |
| ASDAS-BT | 0.06 | 0.98 (0.98, 0.99) | 0.90 (0.90, 0.91) |
| ASDAS–C1 | −0.47 | 0.87 (0.07, 0.96) | 0.56 (0.55, 0.57) |
| ASDAS-C2 | −1.81 | 0.52 (−0.08, 0.81) | 0.32 (0.32, 0.33) |
| ASDAS-C3 | 0.17 | 0.97 (0.90, 0.98) | 0.84 (0.83,0.84) |
| . | . | Agreement between continuous alternative ASDAS formulae with original-ASDAS (N = 823 patients, 2647 observations) . | Agreement between alternative ASDAS formulae with original-ASDAS-defined states of disease activity (N = 823 patients, 2647 observations) . |
|---|---|---|---|
| . | Mean difference with original-ASDAS . | ICC (95% CI) . | Weighted kappa (95% CI) . |
| ASDAS-Q1 | 0.12 | 0.97 (0.94, 0.98) | 0.86 (0.85, 0.87) |
| ASDAS-Q2 | 0.08 | 0.98 (0.97, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q14 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q23 | 0.12 | 0.98 (0.95, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q26 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q145 | 0.07 | 0.98 (0.97, 0.99) | 0.89 (0.88, 0.90) |
| ASDAS-Q236 | 0.10 | 0.98 (0.96, 0.99) | 0.89 (0.88, 0.89) |
| ASDAS-BT | 0.06 | 0.98 (0.98, 0.99) | 0.90 (0.90, 0.91) |
| ASDAS–C1 | −0.47 | 0.87 (0.07, 0.96) | 0.56 (0.55, 0.57) |
| ASDAS-C2 | −1.81 | 0.52 (−0.08, 0.81) | 0.32 (0.32, 0.33) |
| ASDAS-C3 | 0.17 | 0.97 (0.90, 0.98) | 0.84 (0.83,0.84) |
Agreement calculated as a continuous score (ICC) and as a categorical variable (ASDAS disease activity states). The alternative-ASDAS formulae were calculated using as a replacement for PGA: question 1 (Q1), Q2, average of Q1 and Q4 (Q14) or Q2 and Q3 (Q23) or Q2 and Q6 (Q26), average of Q1, Q4 and Q5 (Q145) or Q2, Q3 and Q6 (Q236) and total score (BT) of the BASDAI, or a constant value (ASDAS-C1, -C2, -C3). ASDAS: Ankylosing Spondylitis Disease Activity Scores; original-ASDAS: ASDAS according to the usual formula [5, 6]; ICC: intraclass correlation coefficient.
| . | . | Agreement between continuous alternative ASDAS formulae with original-ASDAS (N = 823 patients, 2647 observations) . | Agreement between alternative ASDAS formulae with original-ASDAS-defined states of disease activity (N = 823 patients, 2647 observations) . |
|---|---|---|---|
| . | Mean difference with original-ASDAS . | ICC (95% CI) . | Weighted kappa (95% CI) . |
| ASDAS-Q1 | 0.12 | 0.97 (0.94, 0.98) | 0.86 (0.85, 0.87) |
| ASDAS-Q2 | 0.08 | 0.98 (0.97, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q14 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q23 | 0.12 | 0.98 (0.95, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q26 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q145 | 0.07 | 0.98 (0.97, 0.99) | 0.89 (0.88, 0.90) |
| ASDAS-Q236 | 0.10 | 0.98 (0.96, 0.99) | 0.89 (0.88, 0.89) |
| ASDAS-BT | 0.06 | 0.98 (0.98, 0.99) | 0.90 (0.90, 0.91) |
| ASDAS–C1 | −0.47 | 0.87 (0.07, 0.96) | 0.56 (0.55, 0.57) |
| ASDAS-C2 | −1.81 | 0.52 (−0.08, 0.81) | 0.32 (0.32, 0.33) |
| ASDAS-C3 | 0.17 | 0.97 (0.90, 0.98) | 0.84 (0.83,0.84) |
| . | . | Agreement between continuous alternative ASDAS formulae with original-ASDAS (N = 823 patients, 2647 observations) . | Agreement between alternative ASDAS formulae with original-ASDAS-defined states of disease activity (N = 823 patients, 2647 observations) . |
|---|---|---|---|
| . | Mean difference with original-ASDAS . | ICC (95% CI) . | Weighted kappa (95% CI) . |
| ASDAS-Q1 | 0.12 | 0.97 (0.94, 0.98) | 0.86 (0.85, 0.87) |
| ASDAS-Q2 | 0.08 | 0.98 (0.97, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q14 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.87, 0.88) |
| ASDAS-Q23 | 0.12 | 0.98 (0.95, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q26 | 0.10 | 0.98 (0.96, 0.99) | 0.88 (0.88, 0.89) |
| ASDAS-Q145 | 0.07 | 0.98 (0.97, 0.99) | 0.89 (0.88, 0.90) |
| ASDAS-Q236 | 0.10 | 0.98 (0.96, 0.99) | 0.89 (0.88, 0.89) |
| ASDAS-BT | 0.06 | 0.98 (0.98, 0.99) | 0.90 (0.90, 0.91) |
| ASDAS–C1 | −0.47 | 0.87 (0.07, 0.96) | 0.56 (0.55, 0.57) |
| ASDAS-C2 | −1.81 | 0.52 (−0.08, 0.81) | 0.32 (0.32, 0.33) |
| ASDAS-C3 | 0.17 | 0.97 (0.90, 0.98) | 0.84 (0.83,0.84) |
Agreement calculated as a continuous score (ICC) and as a categorical variable (ASDAS disease activity states). The alternative-ASDAS formulae were calculated using as a replacement for PGA: question 1 (Q1), Q2, average of Q1 and Q4 (Q14) or Q2 and Q3 (Q23) or Q2 and Q6 (Q26), average of Q1, Q4 and Q5 (Q145) or Q2, Q3 and Q6 (Q236) and total score (BT) of the BASDAI, or a constant value (ASDAS-C1, -C2, -C3). ASDAS: Ankylosing Spondylitis Disease Activity Scores; original-ASDAS: ASDAS according to the usual formula [5, 6]; ICC: intraclass correlation coefficient.
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