. | Univariate . | ORBI risk score adjustment . | |||||||
---|---|---|---|---|---|---|---|---|---|
. | Early CS . | Late CS . | |||||||
. | OR . | 95% CI . | p . | OR . | 95% CI . | p . | OR . | 95% CI . | p . |
ProANP (pmol/l), per two-fold increase | 3.21 | (2.64– 3.91) | <0.0001 | 2.54 | (1.98–3.25) | <0.0001 | 1.82 | (1.34–2.48) | 0.0001 |
Copeptin (pmol/l), per two-fold increase | 2.66 | (2.27–3.11) | <0.0001 | 1.33 | (1.15–1.52) | <0.0001 | 1.19 | (1.01–1.40) | 0.04 |
MRproADM (nmol/l), per two-fold increase | 2.96 | (2.37–3.70) | <0.0001 | 4.16 | (3.04–5.69) | <0.0001 | 3.13 | (2.12–4.63) | <0.0001 |
ST2 (ng/ml), per two-fold increase | 1.61 | (1.36–1.91) | <0.0001 | 2.40 | (1.94–2.97) | <0.0001 | 1.90 | (1.45–2.49) | <0.0001 |
. | Univariate . | ORBI risk score adjustment . | |||||||
---|---|---|---|---|---|---|---|---|---|
. | Early CS . | Late CS . | |||||||
. | OR . | 95% CI . | p . | OR . | 95% CI . | p . | OR . | 95% CI . | p . |
ProANP (pmol/l), per two-fold increase | 3.21 | (2.64– 3.91) | <0.0001 | 2.54 | (1.98–3.25) | <0.0001 | 1.82 | (1.34–2.48) | 0.0001 |
Copeptin (pmol/l), per two-fold increase | 2.66 | (2.27–3.11) | <0.0001 | 1.33 | (1.15–1.52) | <0.0001 | 1.19 | (1.01–1.40) | 0.04 |
MRproADM (nmol/l), per two-fold increase | 2.96 | (2.37–3.70) | <0.0001 | 4.16 | (3.04–5.69) | <0.0001 | 3.13 | (2.12–4.63) | <0.0001 |
ST2 (ng/ml), per two-fold increase | 1.61 | (1.36–1.91) | <0.0001 | 2.40 | (1.94–2.97) | <0.0001 | 1.90 | (1.45–2.49) | <0.0001 |
CI: confidence interval; CS: cardiogenic shock; MRproADM: mid-regional pro-adrenomedullin; OR: odds ratio; ORBI: Observatoire Régional Breton sur l’Infarctus; PCI: percutaneous intervention; PP: pulse pressure; proANP: pro-atrial natriuretic peptide; sBP: systolic blood pressure; ST2: stimulation-2; TIA: transient ischaemic attack; TIMI: Thrombolysis in Myocardial Infarction.
Multivariable logistic regression models. The combination of age>70 years old, previous stroke/TIA, presentation as cardiac arrest, anterior myocardial infarction, first medical contact-to-PCI delay>90 min, Killip Class on admission, heart rate >90/min on admission, sBP<125 mm Hg and PP<45 mm Hg on admission, glycaemia>10 mmol/l on admission, culprit lesion of the left main, post-PCI TIMI flow<3 comprised the ORBI risk score.
. | Univariate . | ORBI risk score adjustment . | |||||||
---|---|---|---|---|---|---|---|---|---|
. | Early CS . | Late CS . | |||||||
. | OR . | 95% CI . | p . | OR . | 95% CI . | p . | OR . | 95% CI . | p . |
ProANP (pmol/l), per two-fold increase | 3.21 | (2.64– 3.91) | <0.0001 | 2.54 | (1.98–3.25) | <0.0001 | 1.82 | (1.34–2.48) | 0.0001 |
Copeptin (pmol/l), per two-fold increase | 2.66 | (2.27–3.11) | <0.0001 | 1.33 | (1.15–1.52) | <0.0001 | 1.19 | (1.01–1.40) | 0.04 |
MRproADM (nmol/l), per two-fold increase | 2.96 | (2.37–3.70) | <0.0001 | 4.16 | (3.04–5.69) | <0.0001 | 3.13 | (2.12–4.63) | <0.0001 |
ST2 (ng/ml), per two-fold increase | 1.61 | (1.36–1.91) | <0.0001 | 2.40 | (1.94–2.97) | <0.0001 | 1.90 | (1.45–2.49) | <0.0001 |
. | Univariate . | ORBI risk score adjustment . | |||||||
---|---|---|---|---|---|---|---|---|---|
. | Early CS . | Late CS . | |||||||
. | OR . | 95% CI . | p . | OR . | 95% CI . | p . | OR . | 95% CI . | p . |
ProANP (pmol/l), per two-fold increase | 3.21 | (2.64– 3.91) | <0.0001 | 2.54 | (1.98–3.25) | <0.0001 | 1.82 | (1.34–2.48) | 0.0001 |
Copeptin (pmol/l), per two-fold increase | 2.66 | (2.27–3.11) | <0.0001 | 1.33 | (1.15–1.52) | <0.0001 | 1.19 | (1.01–1.40) | 0.04 |
MRproADM (nmol/l), per two-fold increase | 2.96 | (2.37–3.70) | <0.0001 | 4.16 | (3.04–5.69) | <0.0001 | 3.13 | (2.12–4.63) | <0.0001 |
ST2 (ng/ml), per two-fold increase | 1.61 | (1.36–1.91) | <0.0001 | 2.40 | (1.94–2.97) | <0.0001 | 1.90 | (1.45–2.49) | <0.0001 |
CI: confidence interval; CS: cardiogenic shock; MRproADM: mid-regional pro-adrenomedullin; OR: odds ratio; ORBI: Observatoire Régional Breton sur l’Infarctus; PCI: percutaneous intervention; PP: pulse pressure; proANP: pro-atrial natriuretic peptide; sBP: systolic blood pressure; ST2: stimulation-2; TIA: transient ischaemic attack; TIMI: Thrombolysis in Myocardial Infarction.
Multivariable logistic regression models. The combination of age>70 years old, previous stroke/TIA, presentation as cardiac arrest, anterior myocardial infarction, first medical contact-to-PCI delay>90 min, Killip Class on admission, heart rate >90/min on admission, sBP<125 mm Hg and PP<45 mm Hg on admission, glycaemia>10 mmol/l on admission, culprit lesion of the left main, post-PCI TIMI flow<3 comprised the ORBI risk score.
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