| . | No CS . | Late CS . | p (Late CS vs no CS) . | Early CS . |
|---|---|---|---|---|
| Number of patients, n . | 2022 . | 64 . | 161 . | |
| Sex (male), n (%) | 1459 (72) | 43 (67) | 0.38 | 116 (72) |
| Age, mean (SD) | 63 (13) | 69 (12) | 0.0002 | 65 (13) |
| Hypertension, n (%) | 872 (44) | 37 (59) | 0.02 | 91 (60) |
| Diabetes, n (%) | 278 (14) | 16 (26) | 0.09 | 24 (16) |
| Smoking, n (%) | 1383 (70) | 49 (82) | 0.009 | 102 (82) |
| Previous stroke/TIA | 138 (6.9) | 9 (15) | 0.06 | 14 (9.3) |
| Body mass index, mean (SD) | 27 (5) | 26 (5) | 0.50 | 26 (5) |
| Known heart failure, n (%) | 67 (3.3) | 6 (9.4) | 0.01 | 14 (8.7) |
| Known ischaemic heart disease, n (%) | 312 (15) | 16 (25) | 0.04 | 33 (21) |
| Known kidney dysfunction, n (%) | 94 (4.7) | 6 (9.4) | 0.09 | 6 (3.7) |
| Admission findings | ||||
| Time from symptom debut to ECG recording, min: median (25th; 75th percentile) | 47 (29; 132) | 104 (37; 810) | 0.26 | 93 (44; 252) |
| Time from ECG recording to acute CAG, min; median (25th; 75th percentile) | 85 (67; 115.5) | 92 (74; 144) | 0.08 | 97 (70; 133) |
| STEMI localisation (ECG) | ||||
| Anterior, n (%) | 764 (42) | 35 (65) | 0.007 | 48 (48) |
| Inferior/posterior, n (%) | 946 (52) | 17 (31) | 45 (45) | |
| Lateral, n (%) | 69 (3.8) | 2 (3.7) | 3 (3.0) | |
| LBBB, n (%) | 45 (2.5) | 0 (0.0) | 3 (3.0) | |
| Pre-hospital anticoagulants | ||||
| Aspirin, n (%) | 1915 (96) | 57 (90) | 0.04 | 111 (73) |
| ADP-receptor inhibitor n (%) | 1696 (85) | 44 (70) | 0.0009 | 72 (48) |
| Heparin, n (%) | 1740 (87) | 52 (83) | 0.27 | 108 (70) |
| Heart rate, mean (SD) | 78 (18) | 89 (24) | <0.0001 | 82 (25) |
| Systolic blood pressure, mean (SD) | 129 (25) | 114 (25) | <0.0001 | 92 (25) |
| Left ventricular ejection fraction, mean (SD) | 47 (11) | 30 (13) | <0.0001 | 31 (14) |
| Comatose cardiac arrest patients, n (%) | 71 (3.5) | 11 (17) | <0.0001 | 92 (57) |
| Number of vessels affected | ||||
| 0-vessel disease, n (%) | 287 (14) | 5 (7.9) | 0.007 | 9 (5.8) |
| 1-vessel disease, n (%) | 1108 (55) | 27 (43) | 54 (35) | |
| 2- vessel disease, n (%) | 388 (19) | 16 (25) | 44 (28) | |
| 3-vessel disease, n (%) | 235 (12) | 15 (24) | 48 (31) | |
| Primary PCI, n (%) | 1615 (80) | 45 (73) | 0.15 | 131 (81) |
| Culprit artery post-PCI TIMI flow | ||||
| 3 | 1489 (95) | 33 (83) | 0.0009 | 106 (88) |
| 2 | 46 (2.9) | 5 (13) | 9 (7.4) | |
| 0–1 | 28 (1.8) | 2 (5.0) | 6 (5.0) | |
| Troponin level (deciles), median (25th; 75th percentile) | 4.0 (2.0; 7.0) | 6.5 (4.5; 8.0) | <0.0001 | 5.5 (3.0; 9.0) |
| . | No CS . | Late CS . | p (Late CS vs no CS) . | Early CS . |
|---|---|---|---|---|
| Number of patients, n . | 2022 . | 64 . | 161 . | |
| Sex (male), n (%) | 1459 (72) | 43 (67) | 0.38 | 116 (72) |
| Age, mean (SD) | 63 (13) | 69 (12) | 0.0002 | 65 (13) |
| Hypertension, n (%) | 872 (44) | 37 (59) | 0.02 | 91 (60) |
| Diabetes, n (%) | 278 (14) | 16 (26) | 0.09 | 24 (16) |
| Smoking, n (%) | 1383 (70) | 49 (82) | 0.009 | 102 (82) |
| Previous stroke/TIA | 138 (6.9) | 9 (15) | 0.06 | 14 (9.3) |
| Body mass index, mean (SD) | 27 (5) | 26 (5) | 0.50 | 26 (5) |
| Known heart failure, n (%) | 67 (3.3) | 6 (9.4) | 0.01 | 14 (8.7) |
| Known ischaemic heart disease, n (%) | 312 (15) | 16 (25) | 0.04 | 33 (21) |
| Known kidney dysfunction, n (%) | 94 (4.7) | 6 (9.4) | 0.09 | 6 (3.7) |
| Admission findings | ||||
| Time from symptom debut to ECG recording, min: median (25th; 75th percentile) | 47 (29; 132) | 104 (37; 810) | 0.26 | 93 (44; 252) |
| Time from ECG recording to acute CAG, min; median (25th; 75th percentile) | 85 (67; 115.5) | 92 (74; 144) | 0.08 | 97 (70; 133) |
| STEMI localisation (ECG) | ||||
| Anterior, n (%) | 764 (42) | 35 (65) | 0.007 | 48 (48) |
| Inferior/posterior, n (%) | 946 (52) | 17 (31) | 45 (45) | |
| Lateral, n (%) | 69 (3.8) | 2 (3.7) | 3 (3.0) | |
| LBBB, n (%) | 45 (2.5) | 0 (0.0) | 3 (3.0) | |
| Pre-hospital anticoagulants | ||||
| Aspirin, n (%) | 1915 (96) | 57 (90) | 0.04 | 111 (73) |
| ADP-receptor inhibitor n (%) | 1696 (85) | 44 (70) | 0.0009 | 72 (48) |
| Heparin, n (%) | 1740 (87) | 52 (83) | 0.27 | 108 (70) |
| Heart rate, mean (SD) | 78 (18) | 89 (24) | <0.0001 | 82 (25) |
| Systolic blood pressure, mean (SD) | 129 (25) | 114 (25) | <0.0001 | 92 (25) |
| Left ventricular ejection fraction, mean (SD) | 47 (11) | 30 (13) | <0.0001 | 31 (14) |
| Comatose cardiac arrest patients, n (%) | 71 (3.5) | 11 (17) | <0.0001 | 92 (57) |
| Number of vessels affected | ||||
| 0-vessel disease, n (%) | 287 (14) | 5 (7.9) | 0.007 | 9 (5.8) |
| 1-vessel disease, n (%) | 1108 (55) | 27 (43) | 54 (35) | |
| 2- vessel disease, n (%) | 388 (19) | 16 (25) | 44 (28) | |
| 3-vessel disease, n (%) | 235 (12) | 15 (24) | 48 (31) | |
| Primary PCI, n (%) | 1615 (80) | 45 (73) | 0.15 | 131 (81) |
| Culprit artery post-PCI TIMI flow | ||||
| 3 | 1489 (95) | 33 (83) | 0.0009 | 106 (88) |
| 2 | 46 (2.9) | 5 (13) | 9 (7.4) | |
| 0–1 | 28 (1.8) | 2 (5.0) | 6 (5.0) | |
| Troponin level (deciles), median (25th; 75th percentile) | 4.0 (2.0; 7.0) | 6.5 (4.5; 8.0) | <0.0001 | 5.5 (3.0; 9.0) |
ADP: adenosine di-phosphate; CAG: coronary angiography; CS: cardiogenic shock; ECG: electrocardiogram; LBBB: left bundle branch block; PCI: percutaneous intervention; SD: standard deviation; STEMI: ST-elevation myocardial infarction; TIA: transient ischaemic attack; TIMI: Thrombolysis in Myocardial Infarction.
| . | No CS . | Late CS . | p (Late CS vs no CS) . | Early CS . |
|---|---|---|---|---|
| Number of patients, n . | 2022 . | 64 . | 161 . | |
| Sex (male), n (%) | 1459 (72) | 43 (67) | 0.38 | 116 (72) |
| Age, mean (SD) | 63 (13) | 69 (12) | 0.0002 | 65 (13) |
| Hypertension, n (%) | 872 (44) | 37 (59) | 0.02 | 91 (60) |
| Diabetes, n (%) | 278 (14) | 16 (26) | 0.09 | 24 (16) |
| Smoking, n (%) | 1383 (70) | 49 (82) | 0.009 | 102 (82) |
| Previous stroke/TIA | 138 (6.9) | 9 (15) | 0.06 | 14 (9.3) |
| Body mass index, mean (SD) | 27 (5) | 26 (5) | 0.50 | 26 (5) |
| Known heart failure, n (%) | 67 (3.3) | 6 (9.4) | 0.01 | 14 (8.7) |
| Known ischaemic heart disease, n (%) | 312 (15) | 16 (25) | 0.04 | 33 (21) |
| Known kidney dysfunction, n (%) | 94 (4.7) | 6 (9.4) | 0.09 | 6 (3.7) |
| Admission findings | ||||
| Time from symptom debut to ECG recording, min: median (25th; 75th percentile) | 47 (29; 132) | 104 (37; 810) | 0.26 | 93 (44; 252) |
| Time from ECG recording to acute CAG, min; median (25th; 75th percentile) | 85 (67; 115.5) | 92 (74; 144) | 0.08 | 97 (70; 133) |
| STEMI localisation (ECG) | ||||
| Anterior, n (%) | 764 (42) | 35 (65) | 0.007 | 48 (48) |
| Inferior/posterior, n (%) | 946 (52) | 17 (31) | 45 (45) | |
| Lateral, n (%) | 69 (3.8) | 2 (3.7) | 3 (3.0) | |
| LBBB, n (%) | 45 (2.5) | 0 (0.0) | 3 (3.0) | |
| Pre-hospital anticoagulants | ||||
| Aspirin, n (%) | 1915 (96) | 57 (90) | 0.04 | 111 (73) |
| ADP-receptor inhibitor n (%) | 1696 (85) | 44 (70) | 0.0009 | 72 (48) |
| Heparin, n (%) | 1740 (87) | 52 (83) | 0.27 | 108 (70) |
| Heart rate, mean (SD) | 78 (18) | 89 (24) | <0.0001 | 82 (25) |
| Systolic blood pressure, mean (SD) | 129 (25) | 114 (25) | <0.0001 | 92 (25) |
| Left ventricular ejection fraction, mean (SD) | 47 (11) | 30 (13) | <0.0001 | 31 (14) |
| Comatose cardiac arrest patients, n (%) | 71 (3.5) | 11 (17) | <0.0001 | 92 (57) |
| Number of vessels affected | ||||
| 0-vessel disease, n (%) | 287 (14) | 5 (7.9) | 0.007 | 9 (5.8) |
| 1-vessel disease, n (%) | 1108 (55) | 27 (43) | 54 (35) | |
| 2- vessel disease, n (%) | 388 (19) | 16 (25) | 44 (28) | |
| 3-vessel disease, n (%) | 235 (12) | 15 (24) | 48 (31) | |
| Primary PCI, n (%) | 1615 (80) | 45 (73) | 0.15 | 131 (81) |
| Culprit artery post-PCI TIMI flow | ||||
| 3 | 1489 (95) | 33 (83) | 0.0009 | 106 (88) |
| 2 | 46 (2.9) | 5 (13) | 9 (7.4) | |
| 0–1 | 28 (1.8) | 2 (5.0) | 6 (5.0) | |
| Troponin level (deciles), median (25th; 75th percentile) | 4.0 (2.0; 7.0) | 6.5 (4.5; 8.0) | <0.0001 | 5.5 (3.0; 9.0) |
| . | No CS . | Late CS . | p (Late CS vs no CS) . | Early CS . |
|---|---|---|---|---|
| Number of patients, n . | 2022 . | 64 . | 161 . | |
| Sex (male), n (%) | 1459 (72) | 43 (67) | 0.38 | 116 (72) |
| Age, mean (SD) | 63 (13) | 69 (12) | 0.0002 | 65 (13) |
| Hypertension, n (%) | 872 (44) | 37 (59) | 0.02 | 91 (60) |
| Diabetes, n (%) | 278 (14) | 16 (26) | 0.09 | 24 (16) |
| Smoking, n (%) | 1383 (70) | 49 (82) | 0.009 | 102 (82) |
| Previous stroke/TIA | 138 (6.9) | 9 (15) | 0.06 | 14 (9.3) |
| Body mass index, mean (SD) | 27 (5) | 26 (5) | 0.50 | 26 (5) |
| Known heart failure, n (%) | 67 (3.3) | 6 (9.4) | 0.01 | 14 (8.7) |
| Known ischaemic heart disease, n (%) | 312 (15) | 16 (25) | 0.04 | 33 (21) |
| Known kidney dysfunction, n (%) | 94 (4.7) | 6 (9.4) | 0.09 | 6 (3.7) |
| Admission findings | ||||
| Time from symptom debut to ECG recording, min: median (25th; 75th percentile) | 47 (29; 132) | 104 (37; 810) | 0.26 | 93 (44; 252) |
| Time from ECG recording to acute CAG, min; median (25th; 75th percentile) | 85 (67; 115.5) | 92 (74; 144) | 0.08 | 97 (70; 133) |
| STEMI localisation (ECG) | ||||
| Anterior, n (%) | 764 (42) | 35 (65) | 0.007 | 48 (48) |
| Inferior/posterior, n (%) | 946 (52) | 17 (31) | 45 (45) | |
| Lateral, n (%) | 69 (3.8) | 2 (3.7) | 3 (3.0) | |
| LBBB, n (%) | 45 (2.5) | 0 (0.0) | 3 (3.0) | |
| Pre-hospital anticoagulants | ||||
| Aspirin, n (%) | 1915 (96) | 57 (90) | 0.04 | 111 (73) |
| ADP-receptor inhibitor n (%) | 1696 (85) | 44 (70) | 0.0009 | 72 (48) |
| Heparin, n (%) | 1740 (87) | 52 (83) | 0.27 | 108 (70) |
| Heart rate, mean (SD) | 78 (18) | 89 (24) | <0.0001 | 82 (25) |
| Systolic blood pressure, mean (SD) | 129 (25) | 114 (25) | <0.0001 | 92 (25) |
| Left ventricular ejection fraction, mean (SD) | 47 (11) | 30 (13) | <0.0001 | 31 (14) |
| Comatose cardiac arrest patients, n (%) | 71 (3.5) | 11 (17) | <0.0001 | 92 (57) |
| Number of vessels affected | ||||
| 0-vessel disease, n (%) | 287 (14) | 5 (7.9) | 0.007 | 9 (5.8) |
| 1-vessel disease, n (%) | 1108 (55) | 27 (43) | 54 (35) | |
| 2- vessel disease, n (%) | 388 (19) | 16 (25) | 44 (28) | |
| 3-vessel disease, n (%) | 235 (12) | 15 (24) | 48 (31) | |
| Primary PCI, n (%) | 1615 (80) | 45 (73) | 0.15 | 131 (81) |
| Culprit artery post-PCI TIMI flow | ||||
| 3 | 1489 (95) | 33 (83) | 0.0009 | 106 (88) |
| 2 | 46 (2.9) | 5 (13) | 9 (7.4) | |
| 0–1 | 28 (1.8) | 2 (5.0) | 6 (5.0) | |
| Troponin level (deciles), median (25th; 75th percentile) | 4.0 (2.0; 7.0) | 6.5 (4.5; 8.0) | <0.0001 | 5.5 (3.0; 9.0) |
ADP: adenosine di-phosphate; CAG: coronary angiography; CS: cardiogenic shock; ECG: electrocardiogram; LBBB: left bundle branch block; PCI: percutaneous intervention; SD: standard deviation; STEMI: ST-elevation myocardial infarction; TIA: transient ischaemic attack; TIMI: Thrombolysis in Myocardial Infarction.
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