Correlation of patient-assessed PRISM with other patient- and physician-reported outcomes.
| Visit . | Number of patients . | Spearman correlation coefficient [95% CI] . | p-value . |
|---|---|---|---|
| PRISM [patient] vs SIBDQ | |||
| Visit 1 (baseline) | 1782 | 0.50 [0.47–0.54] | <0.0001 |
| Visit 2 (Month 6) | 1558 | 0.52 [0.48–0.56] | <0.0001 |
| Visit 3 (Month 12) | 1413 | 0.54 [0.50–0.58] | <0.0001 |
| Visit 4 (Month 18) | 1299 | 0.55 [0.51–0.59] | <0.0001 |
| Visit 5 (Month 24) | 1247 | 0.55 [0.51–0.59] | <0.0001 |
| PRISM [patient] vs PHQ-9 | |||
| Visit 1 (baseline) | 1788 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 2 (Month 6) | 1562 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 3 (Month 12) | 1415 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1301 | -0.44 [-0.48–-0.40] | <0.0001 |
| Visit 5 (Month 24) | 1247 | -0.43 [-0.47–-0.38] | <0.0001 |
| PRISM [patient] vs RFIPC | |||
| Visit 1 (baseline) | 1775 | -0.40 [-0.44–-0.36] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.39 [-0.43–-0.35] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 4 (Month 18) | 1298 | -0.45 [-0.49–-0.41] | <0.0001 |
| Visit 5 (Month 24) | 1242 | -0.46 [-0.50–-0.42] | <0.0001 |
| PRISM [patient] vs P-SCCAI | |||
| Visit 1 (baseline) | 1783 | -0.43 [-0.47–-0.40] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.49 [-0.52–-0.45] | <0.0001 |
| Visit 3 (Month 12) | 1413 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 4 (Month 18) | 1297 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 5 (Month 24) | 1240 | -0.50 [-0.54–-0.45] | <0.0001 |
| PRISM [patient] vs SCCAI | |||
| Visit 1 (baseline) | 1790 | -0.38 [-0.42–-0.34] | <0.0001 |
| Visit 2 (Month 6) | 1557 | -0.43 [-0.47–-0.39] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1299 | -0.43 [-0.47–-0.38] | <0.0001 |
| Visit 5 (Month 24) | 1246 | -0.44 [-0.48–-0.39] | <0.0001 |
| Visit . | Number of patients . | Spearman correlation coefficient [95% CI] . | p-value . |
|---|---|---|---|
| PRISM [patient] vs SIBDQ | |||
| Visit 1 (baseline) | 1782 | 0.50 [0.47–0.54] | <0.0001 |
| Visit 2 (Month 6) | 1558 | 0.52 [0.48–0.56] | <0.0001 |
| Visit 3 (Month 12) | 1413 | 0.54 [0.50–0.58] | <0.0001 |
| Visit 4 (Month 18) | 1299 | 0.55 [0.51–0.59] | <0.0001 |
| Visit 5 (Month 24) | 1247 | 0.55 [0.51–0.59] | <0.0001 |
| PRISM [patient] vs PHQ-9 | |||
| Visit 1 (baseline) | 1788 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 2 (Month 6) | 1562 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 3 (Month 12) | 1415 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1301 | -0.44 [-0.48–-0.40] | <0.0001 |
| Visit 5 (Month 24) | 1247 | -0.43 [-0.47–-0.38] | <0.0001 |
| PRISM [patient] vs RFIPC | |||
| Visit 1 (baseline) | 1775 | -0.40 [-0.44–-0.36] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.39 [-0.43–-0.35] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 4 (Month 18) | 1298 | -0.45 [-0.49–-0.41] | <0.0001 |
| Visit 5 (Month 24) | 1242 | -0.46 [-0.50–-0.42] | <0.0001 |
| PRISM [patient] vs P-SCCAI | |||
| Visit 1 (baseline) | 1783 | -0.43 [-0.47–-0.40] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.49 [-0.52–-0.45] | <0.0001 |
| Visit 3 (Month 12) | 1413 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 4 (Month 18) | 1297 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 5 (Month 24) | 1240 | -0.50 [-0.54–-0.45] | <0.0001 |
| PRISM [patient] vs SCCAI | |||
| Visit 1 (baseline) | 1790 | -0.38 [-0.42–-0.34] | <0.0001 |
| Visit 2 (Month 6) | 1557 | -0.43 [-0.47–-0.39] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1299 | -0.43 [-0.47–-0.38] | <0.0001 |
| Visit 5 (Month 24) | 1246 | -0.44 [-0.48–-0.39] | <0.0001 |
CI, confidence interval; PRISM, Pictorial Representation of Illness and Self-Measure; PHQ-9, Patient Health Questionnaire; P-SCCAI, patient-modified SCCAI; RFIPC, Rating Form of IBD Patient Concerns; SCCAI, Simple Clinical Colitis Activity Index; SIBDQ, Short Inflammatory Bowel Disease Questionnaire.
Correlation of patient-assessed PRISM with other patient- and physician-reported outcomes.
| Visit . | Number of patients . | Spearman correlation coefficient [95% CI] . | p-value . |
|---|---|---|---|
| PRISM [patient] vs SIBDQ | |||
| Visit 1 (baseline) | 1782 | 0.50 [0.47–0.54] | <0.0001 |
| Visit 2 (Month 6) | 1558 | 0.52 [0.48–0.56] | <0.0001 |
| Visit 3 (Month 12) | 1413 | 0.54 [0.50–0.58] | <0.0001 |
| Visit 4 (Month 18) | 1299 | 0.55 [0.51–0.59] | <0.0001 |
| Visit 5 (Month 24) | 1247 | 0.55 [0.51–0.59] | <0.0001 |
| PRISM [patient] vs PHQ-9 | |||
| Visit 1 (baseline) | 1788 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 2 (Month 6) | 1562 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 3 (Month 12) | 1415 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1301 | -0.44 [-0.48–-0.40] | <0.0001 |
| Visit 5 (Month 24) | 1247 | -0.43 [-0.47–-0.38] | <0.0001 |
| PRISM [patient] vs RFIPC | |||
| Visit 1 (baseline) | 1775 | -0.40 [-0.44–-0.36] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.39 [-0.43–-0.35] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 4 (Month 18) | 1298 | -0.45 [-0.49–-0.41] | <0.0001 |
| Visit 5 (Month 24) | 1242 | -0.46 [-0.50–-0.42] | <0.0001 |
| PRISM [patient] vs P-SCCAI | |||
| Visit 1 (baseline) | 1783 | -0.43 [-0.47–-0.40] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.49 [-0.52–-0.45] | <0.0001 |
| Visit 3 (Month 12) | 1413 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 4 (Month 18) | 1297 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 5 (Month 24) | 1240 | -0.50 [-0.54–-0.45] | <0.0001 |
| PRISM [patient] vs SCCAI | |||
| Visit 1 (baseline) | 1790 | -0.38 [-0.42–-0.34] | <0.0001 |
| Visit 2 (Month 6) | 1557 | -0.43 [-0.47–-0.39] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1299 | -0.43 [-0.47–-0.38] | <0.0001 |
| Visit 5 (Month 24) | 1246 | -0.44 [-0.48–-0.39] | <0.0001 |
| Visit . | Number of patients . | Spearman correlation coefficient [95% CI] . | p-value . |
|---|---|---|---|
| PRISM [patient] vs SIBDQ | |||
| Visit 1 (baseline) | 1782 | 0.50 [0.47–0.54] | <0.0001 |
| Visit 2 (Month 6) | 1558 | 0.52 [0.48–0.56] | <0.0001 |
| Visit 3 (Month 12) | 1413 | 0.54 [0.50–0.58] | <0.0001 |
| Visit 4 (Month 18) | 1299 | 0.55 [0.51–0.59] | <0.0001 |
| Visit 5 (Month 24) | 1247 | 0.55 [0.51–0.59] | <0.0001 |
| PRISM [patient] vs PHQ-9 | |||
| Visit 1 (baseline) | 1788 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 2 (Month 6) | 1562 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 3 (Month 12) | 1415 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1301 | -0.44 [-0.48–-0.40] | <0.0001 |
| Visit 5 (Month 24) | 1247 | -0.43 [-0.47–-0.38] | <0.0001 |
| PRISM [patient] vs RFIPC | |||
| Visit 1 (baseline) | 1775 | -0.40 [-0.44–-0.36] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.39 [-0.43–-0.35] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.37] | <0.0001 |
| Visit 4 (Month 18) | 1298 | -0.45 [-0.49–-0.41] | <0.0001 |
| Visit 5 (Month 24) | 1242 | -0.46 [-0.50–-0.42] | <0.0001 |
| PRISM [patient] vs P-SCCAI | |||
| Visit 1 (baseline) | 1783 | -0.43 [-0.47–-0.40] | <0.0001 |
| Visit 2 (Month 6) | 1555 | -0.49 [-0.52–-0.45] | <0.0001 |
| Visit 3 (Month 12) | 1413 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 4 (Month 18) | 1297 | -0.49 [-0.53–-0.45] | <0.0001 |
| Visit 5 (Month 24) | 1240 | -0.50 [-0.54–-0.45] | <0.0001 |
| PRISM [patient] vs SCCAI | |||
| Visit 1 (baseline) | 1790 | -0.38 [-0.42–-0.34] | <0.0001 |
| Visit 2 (Month 6) | 1557 | -0.43 [-0.47–-0.39] | <0.0001 |
| Visit 3 (Month 12) | 1409 | -0.41 [-0.45–-0.36] | <0.0001 |
| Visit 4 (Month 18) | 1299 | -0.43 [-0.47–-0.38] | <0.0001 |
| Visit 5 (Month 24) | 1246 | -0.44 [-0.48–-0.39] | <0.0001 |
CI, confidence interval; PRISM, Pictorial Representation of Illness and Self-Measure; PHQ-9, Patient Health Questionnaire; P-SCCAI, patient-modified SCCAI; RFIPC, Rating Form of IBD Patient Concerns; SCCAI, Simple Clinical Colitis Activity Index; SIBDQ, Short Inflammatory Bowel Disease Questionnaire.
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