Inverse-probability of Treatment Weighted Models for the Duration of Antibiotic Therapy on Patient Outcomes
| . | Predicted Probability of Outcome . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Outcome . | Shorter Course . | Longer Course . | Average Treatment Effecta . | Odds Ratio . | 95% Confidence Interval . | P value . | |
| Composite primary outcome | 13.5% | 11.1% | 2.4% | 1.25 | .65 | 2.40 | .5050 |
| Rehospitalization for the same infection | 2.0% | 3.8% | −1.9% | 0.51 | .05 | 5.06 | .5630 |
| Restarted antibiotics for the same infection | 13.5% | 8.8% | 4.7% | 1.62 | 1.01 | 2.61 | .0460 |
| Clostridioides difficile infection | 4.4% | 1.1% | 3.3% | 4.01 | 2.12 | 7.59 | <.0001 |
| . | Predicted Probability of Outcome . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Outcome . | Shorter Course . | Longer Course . | Average Treatment Effecta . | Odds Ratio . | 95% Confidence Interval . | P value . | |
| Composite primary outcome | 13.5% | 11.1% | 2.4% | 1.25 | .65 | 2.40 | .5050 |
| Rehospitalization for the same infection | 2.0% | 3.8% | −1.9% | 0.51 | .05 | 5.06 | .5630 |
| Restarted antibiotics for the same infection | 13.5% | 8.8% | 4.7% | 1.62 | 1.01 | 2.61 | .0460 |
| Clostridioides difficile infection | 4.4% | 1.1% | 3.3% | 4.01 | 2.12 | 7.59 | <.0001 |
All-cause mortality and antibiotic-related adverse events leading to change in antibiotic therapy not included in this analysis due to there being no cases with these outcomes in the shorter duration group.
aInterpreted as an absolute difference of the predicted probabilities.
Inverse-probability of Treatment Weighted Models for the Duration of Antibiotic Therapy on Patient Outcomes
| . | Predicted Probability of Outcome . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Outcome . | Shorter Course . | Longer Course . | Average Treatment Effecta . | Odds Ratio . | 95% Confidence Interval . | P value . | |
| Composite primary outcome | 13.5% | 11.1% | 2.4% | 1.25 | .65 | 2.40 | .5050 |
| Rehospitalization for the same infection | 2.0% | 3.8% | −1.9% | 0.51 | .05 | 5.06 | .5630 |
| Restarted antibiotics for the same infection | 13.5% | 8.8% | 4.7% | 1.62 | 1.01 | 2.61 | .0460 |
| Clostridioides difficile infection | 4.4% | 1.1% | 3.3% | 4.01 | 2.12 | 7.59 | <.0001 |
| . | Predicted Probability of Outcome . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Outcome . | Shorter Course . | Longer Course . | Average Treatment Effecta . | Odds Ratio . | 95% Confidence Interval . | P value . | |
| Composite primary outcome | 13.5% | 11.1% | 2.4% | 1.25 | .65 | 2.40 | .5050 |
| Rehospitalization for the same infection | 2.0% | 3.8% | −1.9% | 0.51 | .05 | 5.06 | .5630 |
| Restarted antibiotics for the same infection | 13.5% | 8.8% | 4.7% | 1.62 | 1.01 | 2.61 | .0460 |
| Clostridioides difficile infection | 4.4% | 1.1% | 3.3% | 4.01 | 2.12 | 7.59 | <.0001 |
All-cause mortality and antibiotic-related adverse events leading to change in antibiotic therapy not included in this analysis due to there being no cases with these outcomes in the shorter duration group.
aInterpreted as an absolute difference of the predicted probabilities.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
