Table 1

Open-source, cross-platform software for visualizing and analyzing CT data

SoftwareURLOperating system(s)Recommended uses; advantagesLimitations
Drishtihttps://github.com/nci/drishtiAll (Windows, Mac OS, Linux)Tools for image viewing, editing, processing, surface and volume rendering, mesh generation, animation; intuitive user interfaceComputationally demanding for volume rendering
SPIERShttps://spiers-software.org/AllTools for slice registration, image viewing, editing, processing, surface rendering, mesh generation, animation; handles large datasets well even on older/slower machinesThree separate modules for aligning, editing, and viewing; only produces meshes
Blenderhttps://www.blender.org/AllTools for editing 3D meshes, animation, video editing; intuitive user interface, customizableLacks tools for basic image processing (requires 3D model)
MeshLabhttp://www.meshlab.net/AllTools for editing, analyzing, and refining 3D meshesAll processes restricted to working with meshes
3D Slicerhttps://www.slicer.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; intuitive user interface, extensible and customizable with a wide number of available modules, actively supported and developedWorks best on machines with faster graphics processing; may require downsampling of data
FIJIhttps://fiji.sc/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; extensible and customizable via the large number of purpose-built plugins availableNot the most intuitive interface for new users; some plugins no longer actively supported/developed
Biomedisahttps://biomedisa.de/Not applicable (browser-based)Semi-automated segmentation, in-browser viewerInterpolates segments between labeled slices (no other image processing features)
MITK Workbenchhttp://mitk.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation, data management; customizable for developersInterface may be challenging for new users
ITK-SNAPhttp://www.itksnap.org/AllTools for manual and semi-automated segmentation; easily navigable user interfaceFeatures limited to those related to segmentation
MANGOhttp://ric.uthscsa.edu/mango/AllTools for image editing, processing, surface and volume rendering, file manipulation; command line accessible, customizable for developersInterface may be challenging for new users
SoftwareURLOperating system(s)Recommended uses; advantagesLimitations
Drishtihttps://github.com/nci/drishtiAll (Windows, Mac OS, Linux)Tools for image viewing, editing, processing, surface and volume rendering, mesh generation, animation; intuitive user interfaceComputationally demanding for volume rendering
SPIERShttps://spiers-software.org/AllTools for slice registration, image viewing, editing, processing, surface rendering, mesh generation, animation; handles large datasets well even on older/slower machinesThree separate modules for aligning, editing, and viewing; only produces meshes
Blenderhttps://www.blender.org/AllTools for editing 3D meshes, animation, video editing; intuitive user interface, customizableLacks tools for basic image processing (requires 3D model)
MeshLabhttp://www.meshlab.net/AllTools for editing, analyzing, and refining 3D meshesAll processes restricted to working with meshes
3D Slicerhttps://www.slicer.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; intuitive user interface, extensible and customizable with a wide number of available modules, actively supported and developedWorks best on machines with faster graphics processing; may require downsampling of data
FIJIhttps://fiji.sc/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; extensible and customizable via the large number of purpose-built plugins availableNot the most intuitive interface for new users; some plugins no longer actively supported/developed
Biomedisahttps://biomedisa.de/Not applicable (browser-based)Semi-automated segmentation, in-browser viewerInterpolates segments between labeled slices (no other image processing features)
MITK Workbenchhttp://mitk.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation, data management; customizable for developersInterface may be challenging for new users
ITK-SNAPhttp://www.itksnap.org/AllTools for manual and semi-automated segmentation; easily navigable user interfaceFeatures limited to those related to segmentation
MANGOhttp://ric.uthscsa.edu/mango/AllTools for image editing, processing, surface and volume rendering, file manipulation; command line accessible, customizable for developersInterface may be challenging for new users
Table 1

Open-source, cross-platform software for visualizing and analyzing CT data

SoftwareURLOperating system(s)Recommended uses; advantagesLimitations
Drishtihttps://github.com/nci/drishtiAll (Windows, Mac OS, Linux)Tools for image viewing, editing, processing, surface and volume rendering, mesh generation, animation; intuitive user interfaceComputationally demanding for volume rendering
SPIERShttps://spiers-software.org/AllTools for slice registration, image viewing, editing, processing, surface rendering, mesh generation, animation; handles large datasets well even on older/slower machinesThree separate modules for aligning, editing, and viewing; only produces meshes
Blenderhttps://www.blender.org/AllTools for editing 3D meshes, animation, video editing; intuitive user interface, customizableLacks tools for basic image processing (requires 3D model)
MeshLabhttp://www.meshlab.net/AllTools for editing, analyzing, and refining 3D meshesAll processes restricted to working with meshes
3D Slicerhttps://www.slicer.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; intuitive user interface, extensible and customizable with a wide number of available modules, actively supported and developedWorks best on machines with faster graphics processing; may require downsampling of data
FIJIhttps://fiji.sc/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; extensible and customizable via the large number of purpose-built plugins availableNot the most intuitive interface for new users; some plugins no longer actively supported/developed
Biomedisahttps://biomedisa.de/Not applicable (browser-based)Semi-automated segmentation, in-browser viewerInterpolates segments between labeled slices (no other image processing features)
MITK Workbenchhttp://mitk.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation, data management; customizable for developersInterface may be challenging for new users
ITK-SNAPhttp://www.itksnap.org/AllTools for manual and semi-automated segmentation; easily navigable user interfaceFeatures limited to those related to segmentation
MANGOhttp://ric.uthscsa.edu/mango/AllTools for image editing, processing, surface and volume rendering, file manipulation; command line accessible, customizable for developersInterface may be challenging for new users
SoftwareURLOperating system(s)Recommended uses; advantagesLimitations
Drishtihttps://github.com/nci/drishtiAll (Windows, Mac OS, Linux)Tools for image viewing, editing, processing, surface and volume rendering, mesh generation, animation; intuitive user interfaceComputationally demanding for volume rendering
SPIERShttps://spiers-software.org/AllTools for slice registration, image viewing, editing, processing, surface rendering, mesh generation, animation; handles large datasets well even on older/slower machinesThree separate modules for aligning, editing, and viewing; only produces meshes
Blenderhttps://www.blender.org/AllTools for editing 3D meshes, animation, video editing; intuitive user interface, customizableLacks tools for basic image processing (requires 3D model)
MeshLabhttp://www.meshlab.net/AllTools for editing, analyzing, and refining 3D meshesAll processes restricted to working with meshes
3D Slicerhttps://www.slicer.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; intuitive user interface, extensible and customizable with a wide number of available modules, actively supported and developedWorks best on machines with faster graphics processing; may require downsampling of data
FIJIhttps://fiji.sc/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation; extensible and customizable via the large number of purpose-built plugins availableNot the most intuitive interface for new users; some plugins no longer actively supported/developed
Biomedisahttps://biomedisa.de/Not applicable (browser-based)Semi-automated segmentation, in-browser viewerInterpolates segments between labeled slices (no other image processing features)
MITK Workbenchhttp://mitk.org/AllTools for image viewing, editing, processing, surface and volume rendering, file manipulation, data management; customizable for developersInterface may be challenging for new users
ITK-SNAPhttp://www.itksnap.org/AllTools for manual and semi-automated segmentation; easily navigable user interfaceFeatures limited to those related to segmentation
MANGOhttp://ric.uthscsa.edu/mango/AllTools for image editing, processing, surface and volume rendering, file manipulation; command line accessible, customizable for developersInterface may be challenging for new users
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