Changes in NaPi-IIb, PiT-1 and PiT-2 mRNA expression levels in the upper intestine of rats with adenine-induced CKD
Transporters . | Normal . | CKD . |
---|---|---|
NaPi-IIb (mmol/mol villin-1) | 8.1 ± 0.5 | 1.2 ± 0.3* |
PiT-1 (mmol/mol villin-1) | 22.0 ± 2.0 | 22.7 ± 1.9 |
PiT-2 (mmol/mol villin-1) | 0.21 ± 0.02 | 0.26 ± 0.05 |
Transporters . | Normal . | CKD . |
---|---|---|
NaPi-IIb (mmol/mol villin-1) | 8.1 ± 0.5 | 1.2 ± 0.3* |
PiT-1 (mmol/mol villin-1) | 22.0 ± 2.0 | 22.7 ± 1.9 |
PiT-2 (mmol/mol villin-1) | 0.21 ± 0.02 | 0.26 ± 0.05 |
Values are expressed as mean ± SE (n = 10).
P < 0.05, significant difference versus normal (Student’s t-test).
Normal, normal rats; CKD, adenine-induced CKD rats.
Changes in NaPi-IIb, PiT-1 and PiT-2 mRNA expression levels in the upper intestine of rats with adenine-induced CKD
Transporters . | Normal . | CKD . |
---|---|---|
NaPi-IIb (mmol/mol villin-1) | 8.1 ± 0.5 | 1.2 ± 0.3* |
PiT-1 (mmol/mol villin-1) | 22.0 ± 2.0 | 22.7 ± 1.9 |
PiT-2 (mmol/mol villin-1) | 0.21 ± 0.02 | 0.26 ± 0.05 |
Transporters . | Normal . | CKD . |
---|---|---|
NaPi-IIb (mmol/mol villin-1) | 8.1 ± 0.5 | 1.2 ± 0.3* |
PiT-1 (mmol/mol villin-1) | 22.0 ± 2.0 | 22.7 ± 1.9 |
PiT-2 (mmol/mol villin-1) | 0.21 ± 0.02 | 0.26 ± 0.05 |
Values are expressed as mean ± SE (n = 10).
P < 0.05, significant difference versus normal (Student’s t-test).
Normal, normal rats; CKD, adenine-induced CKD rats.
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