Table 1. Open in new tab Patient...

Patient/Sample Identifier

Clinical Area/Geographic Region

Isolate Species and Identifier

MLST

Specimen Site

Month of Isolation^a

Temporal- spatial Clustering

Hematology

Kox-A Kox-A.2 Kox-A.3 Kox-A.4

ST138 ST138 ST138 ST138

Urine BAL Rectal screen blood

18–20

2 2 2 2

Hematology

Kox-B Kox-B.2

ST138 ST138

Rectal screen Rectal screen

2 2

Hematology

Kox-C

ST138

Rectal screen

Hematology

Kox-D

ST138

Rectal screen

Hematology

Kox-E

ST138

Rectal screen

Hematology

Kox-F

ST138

Rectal screen

Hematology

Kox-G

ST138

Rectal screen

Hematology

Kox-H

ST138

Rectal screen

Hematology

Kox-I Kox-I.2

ST138 ST138

Rectal screen Rectal screen

2 2

Hematology

Kox-J

ST138

Rectal screen

Hematology

Kox-K

ST138

Rectal screen

Cardiothoracic/ITU

Kox-Z

ST138

Urine

Cardiothoracic/ITU

Kox-Y

ST138

Wound

Cardiothoracic/ITU

Kox-X

ST138

Throat swab

Neurology

Ecl-W

ST66

Rectal screen

Renal

Eco-V

ST101

Rectal screen

Water_U^b

Northwest England

Kox-U

ST236

Wastewater

−1

Remote site

Scot_T

Scotland

Kpn-T

ST147

Rectal screen

Remote site

Lon_S

London center 2

Eco-S

ST405

Rectal screen

Remote site

Table 1.

Open in new tab

Patient Characteristics, Sites, or Specimens That GES-5 Producers Were Isolated From and the Month of Isolation (Relative to the Study Hospital Investigation)

Patient/Sample Identifier	Clinical Area/Geographic Region	Isolate Species and Identifier	MLST	Specimen Site	Month of Isolation^a	Temporal- spatial Clustering
A	Hematology	Kox-A Kox-A.2 Kox-A.3 Kox-A.4	ST138 ST138 ST138 ST138	Urine BAL Rectal screen blood	18–20	2 2 2 2
B	Hematology	Kox-B Kox-B.2	ST138 ST138	Rectal screen Rectal screen	19	2 2
C	Hematology	Kox-C	ST138	Rectal screen	19	2
D	Hematology	Kox-D	ST138	Rectal screen	19	2
E	Hematology	Kox-E	ST138	Rectal screen	19	2
F	Hematology	Kox-F	ST138	Rectal screen	19	2
G	Hematology	Kox-G	ST138	Rectal screen	20	2
H	Hematology	Kox-H	ST138	Rectal screen	20	2
I	Hematology	Kox-I Kox-I.2	ST138 ST138	Rectal screen Rectal screen	21	2 2
J	Hematology	Kox-J	ST138	Rectal screen	21	2
K	Hematology	Kox-K	ST138	Rectal screen	22	2
Z	Cardiothoracic/ITU	Kox-Z	ST138	Urine	6	1
Y	Cardiothoracic/ITU	Kox-Y	ST138	Wound	10	1
X	Cardiothoracic/ITU	Kox-X	ST138	Throat swab	10	1
W	Neurology	Ecl-W	ST66	Rectal screen	21	2a
V	Renal	Eco-V	ST101	Rectal screen	25	2a
Water_U^b	Northwest England	Kox-U	ST236	Wastewater	−1	Remote site
Scot_T	Scotland	Kpn-T	ST147	Rectal screen	19	Remote site
Lon_S	London center 2	Eco-S	ST405	Rectal screen	+3	Remote site

Patient/Sample Identifier	Clinical Area/Geographic Region	Isolate Species and Identifier	MLST	Specimen Site	Month of Isolation^a	Temporal- spatial Clustering
A	Hematology	Kox-A Kox-A.2 Kox-A.3 Kox-A.4	ST138 ST138 ST138 ST138	Urine BAL Rectal screen blood	18–20	2 2 2 2
B	Hematology	Kox-B Kox-B.2	ST138 ST138	Rectal screen Rectal screen	19	2 2
C	Hematology	Kox-C	ST138	Rectal screen	19	2
D	Hematology	Kox-D	ST138	Rectal screen	19	2
E	Hematology	Kox-E	ST138	Rectal screen	19	2
F	Hematology	Kox-F	ST138	Rectal screen	19	2
G	Hematology	Kox-G	ST138	Rectal screen	20	2
H	Hematology	Kox-H	ST138	Rectal screen	20	2
I	Hematology	Kox-I Kox-I.2	ST138 ST138	Rectal screen Rectal screen	21	2 2
J	Hematology	Kox-J	ST138	Rectal screen	21	2
K	Hematology	Kox-K	ST138	Rectal screen	22	2
Z	Cardiothoracic/ITU	Kox-Z	ST138	Urine	6	1
Y	Cardiothoracic/ITU	Kox-Y	ST138	Wound	10	1
X	Cardiothoracic/ITU	Kox-X	ST138	Throat swab	10	1
W	Neurology	Ecl-W	ST66	Rectal screen	21	2a
V	Renal	Eco-V	ST101	Rectal screen	25	2a
Water_U^b	Northwest England	Kox-U	ST236	Wastewater	−1	Remote site
Scot_T	Scotland	Kpn-T	ST147	Rectal screen	19	Remote site
Lon_S	London center 2	Eco-S	ST405	Rectal screen	+3	Remote site

Bacterial identifiers, including species codes, are shown alongside multilocus sequence types. Temporal cluster assignations were assigned around 2 clusters from the same hospital: 1, the historical cluster; 2, the cluster associated with the recognized index case; 2a, non–Klebsiella oxytoca isolated at the same National Health Service trust around the same time as cluster 2. The temporally diverse isolates from geographically remote sites in the United Kingdom are also shown (remote sites).

Abbreviations: BAL, bronchoalveolar lavage; Ecl, Enterobacter cloacae; Eco, Escherichia coli; ITU, intensive therapy unit, Kox, Klebsiella oxytoca; Kpn, Klebsiella pneumoniae; MLST, multilocus sequence typing; ST, sequence type.

^aSee timeline (Figure 1A).

^bPublished previously [19].

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