| . | . | . | . | . | . | Discovery Set . | . | . | . | Validation Set . | . | Meta . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP . | Gene . | Chr . | Position (hg19) . | Ref Allele . | Alt Allele . | Case AAF . | Control AAF . | OR . | P-value . | OR . | P-value . | P-value . |
| IDH mutated glioma | ||||||||||||
| rs5839764 | D2HGDH | 2 | 242703618 | C | G | 0.458 | 0.372 | 1.512 | 3.62E-07 | 1.564 | 0.0001264 | 2.82E-10 |
| IDH mutated non-codeleted glioma | ||||||||||||
| rs1106639 | D2HGDH | 2 | 242690675 | G | A | 0.337 | 0.260 | 1.705 | 3.20E-06 | 1.718 | 0.002258 | 4.96E-08 |
| Triple-positive glioma (IDH mutated, TERT mutated, 1p19q codeleted) | ||||||||||||
| rs111976262 | FAM20C | 7 | 188634 | C | A | 0.074 | 0.031 | 3.516 | 1.02E-06 | 3.051 | 0.001252 | 9.56E-09 |
| IDH wild-type glioma | ||||||||||||
| rs4809313 | GMEB2 | 20 | 62238086 | G | A | 0.173 | 0.232 | 0.663 | 1.10E-06 | 0.627 | 4.79E-05 | 2.60E-10 |
| . | . | . | . | . | . | Discovery Set . | . | . | . | Validation Set . | . | Meta . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP . | Gene . | Chr . | Position (hg19) . | Ref Allele . | Alt Allele . | Case AAF . | Control AAF . | OR . | P-value . | OR . | P-value . | P-value . |
| IDH mutated glioma | ||||||||||||
| rs5839764 | D2HGDH | 2 | 242703618 | C | G | 0.458 | 0.372 | 1.512 | 3.62E-07 | 1.564 | 0.0001264 | 2.82E-10 |
| IDH mutated non-codeleted glioma | ||||||||||||
| rs1106639 | D2HGDH | 2 | 242690675 | G | A | 0.337 | 0.260 | 1.705 | 3.20E-06 | 1.718 | 0.002258 | 4.96E-08 |
| Triple-positive glioma (IDH mutated, TERT mutated, 1p19q codeleted) | ||||||||||||
| rs111976262 | FAM20C | 7 | 188634 | C | A | 0.074 | 0.031 | 3.516 | 1.02E-06 | 3.051 | 0.001252 | 9.56E-09 |
| IDH wild-type glioma | ||||||||||||
| rs4809313 | GMEB2 | 20 | 62238086 | G | A | 0.173 | 0.232 | 0.663 | 1.10E-06 | 0.627 | 4.79E-05 | 2.60E-10 |
Abbreviations: Alt = alternate; AAF = alternate allele frequency; Chr = chromosome; OR = odds ratio; Ref = reference; SNP = single nucleotide polymorphism.
| . | . | . | . | . | . | Discovery Set . | . | . | . | Validation Set . | . | Meta . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP . | Gene . | Chr . | Position (hg19) . | Ref Allele . | Alt Allele . | Case AAF . | Control AAF . | OR . | P-value . | OR . | P-value . | P-value . |
| IDH mutated glioma | ||||||||||||
| rs5839764 | D2HGDH | 2 | 242703618 | C | G | 0.458 | 0.372 | 1.512 | 3.62E-07 | 1.564 | 0.0001264 | 2.82E-10 |
| IDH mutated non-codeleted glioma | ||||||||||||
| rs1106639 | D2HGDH | 2 | 242690675 | G | A | 0.337 | 0.260 | 1.705 | 3.20E-06 | 1.718 | 0.002258 | 4.96E-08 |
| Triple-positive glioma (IDH mutated, TERT mutated, 1p19q codeleted) | ||||||||||||
| rs111976262 | FAM20C | 7 | 188634 | C | A | 0.074 | 0.031 | 3.516 | 1.02E-06 | 3.051 | 0.001252 | 9.56E-09 |
| IDH wild-type glioma | ||||||||||||
| rs4809313 | GMEB2 | 20 | 62238086 | G | A | 0.173 | 0.232 | 0.663 | 1.10E-06 | 0.627 | 4.79E-05 | 2.60E-10 |
| . | . | . | . | . | . | Discovery Set . | . | . | . | Validation Set . | . | Meta . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP . | Gene . | Chr . | Position (hg19) . | Ref Allele . | Alt Allele . | Case AAF . | Control AAF . | OR . | P-value . | OR . | P-value . | P-value . |
| IDH mutated glioma | ||||||||||||
| rs5839764 | D2HGDH | 2 | 242703618 | C | G | 0.458 | 0.372 | 1.512 | 3.62E-07 | 1.564 | 0.0001264 | 2.82E-10 |
| IDH mutated non-codeleted glioma | ||||||||||||
| rs1106639 | D2HGDH | 2 | 242690675 | G | A | 0.337 | 0.260 | 1.705 | 3.20E-06 | 1.718 | 0.002258 | 4.96E-08 |
| Triple-positive glioma (IDH mutated, TERT mutated, 1p19q codeleted) | ||||||||||||
| rs111976262 | FAM20C | 7 | 188634 | C | A | 0.074 | 0.031 | 3.516 | 1.02E-06 | 3.051 | 0.001252 | 9.56E-09 |
| IDH wild-type glioma | ||||||||||||
| rs4809313 | GMEB2 | 20 | 62238086 | G | A | 0.173 | 0.232 | 0.663 | 1.10E-06 | 0.627 | 4.79E-05 | 2.60E-10 |
Abbreviations: Alt = alternate; AAF = alternate allele frequency; Chr = chromosome; OR = odds ratio; Ref = reference; SNP = single nucleotide polymorphism.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
