Table 4. 

Factors Associated With Liver Fibrosis Among HIV-Infected Females Patients Attending the AIDC and GPC Care Clinics in Urban and Rural Uganda (2015–2017)

Urban ClinicRural Clinic
Explanatory variableAdjusted AnalysisP ValueAdjusted AnalysisP Value
OR (95% CI)OR (95% CI)
Age (10-y increase)1.3 (1.1–1.6).0081.3 (1.0–1.6).052
Ever used alcohol0.6 (0.4–0.9).0160.6 (0.4–1.1).082
Ever used tobacco1.5 (0.9–2.5).0912.9 (1.5–5.9).003
Ever used herbal medicine1.2 (0.7–1.9).4741.0 (0.6–1.8).949
Hepatitis B surface antigen positive1.1 (0.7–2.0).6120.4 (0.1–1.1).072
Hepatitis C antibody positive1.9 (0.6–6.0).2632.2 (0.6–9.0).259
On ART--0.6 (0.1–4.9).594
Detectable HIV viral load (≥1000 copies/mL)1.4 (0.6–3.3).4031.4 (0.7–2.9).404
Elevated liver transaminasesa2.3 (1.3–3.9).0022.4 (1.1–5.3).028
Urban ClinicRural Clinic
Explanatory variableAdjusted AnalysisP ValueAdjusted AnalysisP Value
OR (95% CI)OR (95% CI)
Age (10-y increase)1.3 (1.1–1.6).0081.3 (1.0–1.6).052
Ever used alcohol0.6 (0.4–0.9).0160.6 (0.4–1.1).082
Ever used tobacco1.5 (0.9–2.5).0912.9 (1.5–5.9).003
Ever used herbal medicine1.2 (0.7–1.9).4741.0 (0.6–1.8).949
Hepatitis B surface antigen positive1.1 (0.7–2.0).6120.4 (0.1–1.1).072
Hepatitis C antibody positive1.9 (0.6–6.0).2632.2 (0.6–9.0).259
On ART--0.6 (0.1–4.9).594
Detectable HIV viral load (≥1000 copies/mL)1.4 (0.6–3.3).4031.4 (0.7–2.9).404
Elevated liver transaminasesa2.3 (1.3–3.9).0022.4 (1.1–5.3).028

Abbreviations: AIDC, Adult Infectious Diseases Clinic; ART, antiretroviral therapy; GPC, General Population Clinic; OR, odds ratio.

aAIDS Clinical Trials Group classification.

Table 4. 

Factors Associated With Liver Fibrosis Among HIV-Infected Females Patients Attending the AIDC and GPC Care Clinics in Urban and Rural Uganda (2015–2017)

Urban ClinicRural Clinic
Explanatory variableAdjusted AnalysisP ValueAdjusted AnalysisP Value
OR (95% CI)OR (95% CI)
Age (10-y increase)1.3 (1.1–1.6).0081.3 (1.0–1.6).052
Ever used alcohol0.6 (0.4–0.9).0160.6 (0.4–1.1).082
Ever used tobacco1.5 (0.9–2.5).0912.9 (1.5–5.9).003
Ever used herbal medicine1.2 (0.7–1.9).4741.0 (0.6–1.8).949
Hepatitis B surface antigen positive1.1 (0.7–2.0).6120.4 (0.1–1.1).072
Hepatitis C antibody positive1.9 (0.6–6.0).2632.2 (0.6–9.0).259
On ART--0.6 (0.1–4.9).594
Detectable HIV viral load (≥1000 copies/mL)1.4 (0.6–3.3).4031.4 (0.7–2.9).404
Elevated liver transaminasesa2.3 (1.3–3.9).0022.4 (1.1–5.3).028
Urban ClinicRural Clinic
Explanatory variableAdjusted AnalysisP ValueAdjusted AnalysisP Value
OR (95% CI)OR (95% CI)
Age (10-y increase)1.3 (1.1–1.6).0081.3 (1.0–1.6).052
Ever used alcohol0.6 (0.4–0.9).0160.6 (0.4–1.1).082
Ever used tobacco1.5 (0.9–2.5).0912.9 (1.5–5.9).003
Ever used herbal medicine1.2 (0.7–1.9).4741.0 (0.6–1.8).949
Hepatitis B surface antigen positive1.1 (0.7–2.0).6120.4 (0.1–1.1).072
Hepatitis C antibody positive1.9 (0.6–6.0).2632.2 (0.6–9.0).259
On ART--0.6 (0.1–4.9).594
Detectable HIV viral load (≥1000 copies/mL)1.4 (0.6–3.3).4031.4 (0.7–2.9).404
Elevated liver transaminasesa2.3 (1.3–3.9).0022.4 (1.1–5.3).028

Abbreviations: AIDC, Adult Infectious Diseases Clinic; ART, antiretroviral therapy; GPC, General Population Clinic; OR, odds ratio.

aAIDS Clinical Trials Group classification.

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