Table 2.

Relationship of clinical characteristics with inflammatory biomarkers.

Interleukin-6
TNF-alpha
Galectin-3
Parametersβ (SE)pβ (SE)pβ (SE)p
Age, years0.06 (0.03)0.0260.05 (0.05)0.28−0.04 (0.04)0.36
Male sex0.56 (0.41)0.181.22 (0.67)0.076−0.51 (0.62)0.42
BMI, kg/m20.06 (0.05)0.190.02 (0.08)0.77−0.03 (0.07)0.76
Hypertension0.54 (0.41)0.20−0.74 (0.69)0.290.18 (0.62)0.77
Diabetes mellitus0.32 (0.51)0.540.78 (0.85)0.37−0.56 (0.77)0.47
Ischemic etiology0.65 (0.47)0.180.60 (0.80)0.46−0.29 (0.72)0.69
Functional class, NYHA0.54 (0.27)0.0520.93 (0.45)0.0470.45 (0.42)0.29
Systolic BP, mmHg0.01 (0.01)0.55−0.03 (0.02)0.21−0.01 (0.02)0.74
Diastolic BP, mmHg0.02 (0.02)0.30−0.03 (0.03)0.23−0.01 (0.02)0.55
LV ejection fraction, %−0.03 (0.03)0.38−0.04 (0.06)0.45−0.01 (0.05)0.89
Interleukin-6
TNF-alpha
Galectin-3
Parametersβ (SE)pβ (SE)pβ (SE)p
Age, years0.06 (0.03)0.0260.05 (0.05)0.28−0.04 (0.04)0.36
Male sex0.56 (0.41)0.181.22 (0.67)0.076−0.51 (0.62)0.42
BMI, kg/m20.06 (0.05)0.190.02 (0.08)0.77−0.03 (0.07)0.76
Hypertension0.54 (0.41)0.20−0.74 (0.69)0.290.18 (0.62)0.77
Diabetes mellitus0.32 (0.51)0.540.78 (0.85)0.37−0.56 (0.77)0.47
Ischemic etiology0.65 (0.47)0.180.60 (0.80)0.46−0.29 (0.72)0.69
Functional class, NYHA0.54 (0.27)0.0520.93 (0.45)0.0470.45 (0.42)0.29
Systolic BP, mmHg0.01 (0.01)0.55−0.03 (0.02)0.21−0.01 (0.02)0.74
Diastolic BP, mmHg0.02 (0.02)0.30−0.03 (0.03)0.23−0.01 (0.02)0.55
LV ejection fraction, %−0.03 (0.03)0.38−0.04 (0.06)0.45−0.01 (0.05)0.89

Data are β coefficients and standard errors (SE), which represent the change in each inflammatory biomarker for one-unit increase in the predictor. Interleukin-6 level values were log transformed.

TNF-alpha: tumor necrosis factor alpha; BMI: body mass index; NYHA: New York Heart Association classification; BP: blood pressure; LV: left ventricle

Table 2.

Relationship of clinical characteristics with inflammatory biomarkers.

Interleukin-6
TNF-alpha
Galectin-3
Parametersβ (SE)pβ (SE)pβ (SE)p
Age, years0.06 (0.03)0.0260.05 (0.05)0.28−0.04 (0.04)0.36
Male sex0.56 (0.41)0.181.22 (0.67)0.076−0.51 (0.62)0.42
BMI, kg/m20.06 (0.05)0.190.02 (0.08)0.77−0.03 (0.07)0.76
Hypertension0.54 (0.41)0.20−0.74 (0.69)0.290.18 (0.62)0.77
Diabetes mellitus0.32 (0.51)0.540.78 (0.85)0.37−0.56 (0.77)0.47
Ischemic etiology0.65 (0.47)0.180.60 (0.80)0.46−0.29 (0.72)0.69
Functional class, NYHA0.54 (0.27)0.0520.93 (0.45)0.0470.45 (0.42)0.29
Systolic BP, mmHg0.01 (0.01)0.55−0.03 (0.02)0.21−0.01 (0.02)0.74
Diastolic BP, mmHg0.02 (0.02)0.30−0.03 (0.03)0.23−0.01 (0.02)0.55
LV ejection fraction, %−0.03 (0.03)0.38−0.04 (0.06)0.45−0.01 (0.05)0.89
Interleukin-6
TNF-alpha
Galectin-3
Parametersβ (SE)pβ (SE)pβ (SE)p
Age, years0.06 (0.03)0.0260.05 (0.05)0.28−0.04 (0.04)0.36
Male sex0.56 (0.41)0.181.22 (0.67)0.076−0.51 (0.62)0.42
BMI, kg/m20.06 (0.05)0.190.02 (0.08)0.77−0.03 (0.07)0.76
Hypertension0.54 (0.41)0.20−0.74 (0.69)0.290.18 (0.62)0.77
Diabetes mellitus0.32 (0.51)0.540.78 (0.85)0.37−0.56 (0.77)0.47
Ischemic etiology0.65 (0.47)0.180.60 (0.80)0.46−0.29 (0.72)0.69
Functional class, NYHA0.54 (0.27)0.0520.93 (0.45)0.0470.45 (0.42)0.29
Systolic BP, mmHg0.01 (0.01)0.55−0.03 (0.02)0.21−0.01 (0.02)0.74
Diastolic BP, mmHg0.02 (0.02)0.30−0.03 (0.03)0.23−0.01 (0.02)0.55
LV ejection fraction, %−0.03 (0.03)0.38−0.04 (0.06)0.45−0.01 (0.05)0.89

Data are β coefficients and standard errors (SE), which represent the change in each inflammatory biomarker for one-unit increase in the predictor. Interleukin-6 level values were log transformed.

TNF-alpha: tumor necrosis factor alpha; BMI: body mass index; NYHA: New York Heart Association classification; BP: blood pressure; LV: left ventricle

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