Table 2.

Exposure or Condition Associated With Pathogens Causing Diarrhea

Exposure or ConditionPathogen(s)
Foodborne
 Foodborne outbreaks in hotels, cruise ships, resorts, restaurants, catered eventsNorovirus, nontyphoidal Salmonella, Clostridium perfringens, Bacillus cereus, Staphylococcus aureus, Campylobacter spp, ETEC, STEC, Listeria, Shigella, Cyclospora cayetanensis, Cryptosporidium spp
 Consumption of unpasteurized milk or dairy productsSalmonella, Campylobacter, Yersinia enterocolitica, S. aureus toxin, Cryptosporidium, and STEC. Listeria is infrequently associated with diarrhea, Brucella (goat milk cheese), Mycobacterium bovis, Coxiella burnetii
 Consumption of raw or undercooked meat or poultrySTEC (beef), C. perfringens (beef, poultry), Salmonella (poultry), Campylobacter (poultry), Yersinia (pork, chitterlings), S. aureus (poultry), and Trichinella spp (pork, wild game meat)
 Consumption of fruits or unpasteurized fruit juices, vegetables, leafy greens, and sproutsSTEC, nontyphoidal Salmonella, Cyclospora, Cryptosporidium, norovirus, hepatitis A, and Listeria monocytogenes
 Consumption of undercooked eggsSalmonella, Shigella (egg salad)
 Consumption of raw shellfishVibrio species, norovirus, hepatitis A, Plesiomonas
Exposure or contact
 Swimming in or drinking untreated fresh waterCampylobacter, Cryptosporidium, Giardia, Shigella, Salmonella, STEC, Plesiomonas shigelloides
 Swimming in recreational water facility with treated waterCryptosporidium and other potentially waterborne pathogens when disinfectant concentrations are inadequately maintained
 Healthcare, long-term care, prison exposure, or employmentNorovirus, Clostridium difficile, Shigella, Cryptosporidium, Giardia, STEC, rotavirus
 Child care center attendance or employmentRotavirus, Cryptosporidium, Giardia, Shigella, STEC
 Recent antimicrobial therapyC. difficile, multidrug-resistant Salmonella
 Travel to resource-challenged countriesEscherichia coli (enteroaggregative, enterotoxigenic, enteroinvasive), Shigella, Typhi and nontyphoidal Salmonella, Campylobacter, Vibrio cholerae, Entamoeba histolytica, Giardia, Blastocystis, Cyclospora, Cystoisospora, Cryptosporidium
 Exposure to house pets with diarrheaCampylobacter, Yersinia
 Exposure to pig feces in certain parts of the worldBalantidium coli
 Contact with young poultry or reptilesNontyphoidal Salmonella
 Visiting a farm or petting zooSTEC, Cryptosporidium, Campylobacter
Exposure or condition
 Age groupRotavirus (6–18 months of age), nontyphoidal Salmonella (infants from birth to 3 months of age and adults >50 years with a history of atherosclerosis), Shigella (1–7 years of age), Campylobacter (young adults)
 Underlying immunocompromising conditionNontyphoidal Salmonella, Cryptosporidium, Campylobacter, Shigella, Yersinia
 Hemochromatosis or hemoglobinopathyY. enterocolitica, Salmonella
 AIDS, immunosuppressive therapiesCryptosporidium, Cyclospora, Cystoisospora, microsporidia, Mycobacterium avium–intercellulare complex, cytomegalovirus
 Anal-genital, oral-anal, or digital-anal contactShigella, Salmonella, Campylobacter, E. histolytica, Giardia lamblia, Cryptosporidium as well as sexually transmitted infections
Exposure or ConditionPathogen(s)
Foodborne
 Foodborne outbreaks in hotels, cruise ships, resorts, restaurants, catered eventsNorovirus, nontyphoidal Salmonella, Clostridium perfringens, Bacillus cereus, Staphylococcus aureus, Campylobacter spp, ETEC, STEC, Listeria, Shigella, Cyclospora cayetanensis, Cryptosporidium spp
 Consumption of unpasteurized milk or dairy productsSalmonella, Campylobacter, Yersinia enterocolitica, S. aureus toxin, Cryptosporidium, and STEC. Listeria is infrequently associated with diarrhea, Brucella (goat milk cheese), Mycobacterium bovis, Coxiella burnetii
 Consumption of raw or undercooked meat or poultrySTEC (beef), C. perfringens (beef, poultry), Salmonella (poultry), Campylobacter (poultry), Yersinia (pork, chitterlings), S. aureus (poultry), and Trichinella spp (pork, wild game meat)
 Consumption of fruits or unpasteurized fruit juices, vegetables, leafy greens, and sproutsSTEC, nontyphoidal Salmonella, Cyclospora, Cryptosporidium, norovirus, hepatitis A, and Listeria monocytogenes
 Consumption of undercooked eggsSalmonella, Shigella (egg salad)
 Consumption of raw shellfishVibrio species, norovirus, hepatitis A, Plesiomonas
Exposure or contact
 Swimming in or drinking untreated fresh waterCampylobacter, Cryptosporidium, Giardia, Shigella, Salmonella, STEC, Plesiomonas shigelloides
 Swimming in recreational water facility with treated waterCryptosporidium and other potentially waterborne pathogens when disinfectant concentrations are inadequately maintained
 Healthcare, long-term care, prison exposure, or employmentNorovirus, Clostridium difficile, Shigella, Cryptosporidium, Giardia, STEC, rotavirus
 Child care center attendance or employmentRotavirus, Cryptosporidium, Giardia, Shigella, STEC
 Recent antimicrobial therapyC. difficile, multidrug-resistant Salmonella
 Travel to resource-challenged countriesEscherichia coli (enteroaggregative, enterotoxigenic, enteroinvasive), Shigella, Typhi and nontyphoidal Salmonella, Campylobacter, Vibrio cholerae, Entamoeba histolytica, Giardia, Blastocystis, Cyclospora, Cystoisospora, Cryptosporidium
 Exposure to house pets with diarrheaCampylobacter, Yersinia
 Exposure to pig feces in certain parts of the worldBalantidium coli
 Contact with young poultry or reptilesNontyphoidal Salmonella
 Visiting a farm or petting zooSTEC, Cryptosporidium, Campylobacter
Exposure or condition
 Age groupRotavirus (6–18 months of age), nontyphoidal Salmonella (infants from birth to 3 months of age and adults >50 years with a history of atherosclerosis), Shigella (1–7 years of age), Campylobacter (young adults)
 Underlying immunocompromising conditionNontyphoidal Salmonella, Cryptosporidium, Campylobacter, Shigella, Yersinia
 Hemochromatosis or hemoglobinopathyY. enterocolitica, Salmonella
 AIDS, immunosuppressive therapiesCryptosporidium, Cyclospora, Cystoisospora, microsporidia, Mycobacterium avium–intercellulare complex, cytomegalovirus
 Anal-genital, oral-anal, or digital-anal contactShigella, Salmonella, Campylobacter, E. histolytica, Giardia lamblia, Cryptosporidium as well as sexually transmitted infections

Abbreviations: ETEC, enterotoxigenic Escherichia coli; STEC, Shiga toxin–producing Escherichia coli.

Table 2.

Exposure or Condition Associated With Pathogens Causing Diarrhea

Exposure or ConditionPathogen(s)
Foodborne
 Foodborne outbreaks in hotels, cruise ships, resorts, restaurants, catered eventsNorovirus, nontyphoidal Salmonella, Clostridium perfringens, Bacillus cereus, Staphylococcus aureus, Campylobacter spp, ETEC, STEC, Listeria, Shigella, Cyclospora cayetanensis, Cryptosporidium spp
 Consumption of unpasteurized milk or dairy productsSalmonella, Campylobacter, Yersinia enterocolitica, S. aureus toxin, Cryptosporidium, and STEC. Listeria is infrequently associated with diarrhea, Brucella (goat milk cheese), Mycobacterium bovis, Coxiella burnetii
 Consumption of raw or undercooked meat or poultrySTEC (beef), C. perfringens (beef, poultry), Salmonella (poultry), Campylobacter (poultry), Yersinia (pork, chitterlings), S. aureus (poultry), and Trichinella spp (pork, wild game meat)
 Consumption of fruits or unpasteurized fruit juices, vegetables, leafy greens, and sproutsSTEC, nontyphoidal Salmonella, Cyclospora, Cryptosporidium, norovirus, hepatitis A, and Listeria monocytogenes
 Consumption of undercooked eggsSalmonella, Shigella (egg salad)
 Consumption of raw shellfishVibrio species, norovirus, hepatitis A, Plesiomonas
Exposure or contact
 Swimming in or drinking untreated fresh waterCampylobacter, Cryptosporidium, Giardia, Shigella, Salmonella, STEC, Plesiomonas shigelloides
 Swimming in recreational water facility with treated waterCryptosporidium and other potentially waterborne pathogens when disinfectant concentrations are inadequately maintained
 Healthcare, long-term care, prison exposure, or employmentNorovirus, Clostridium difficile, Shigella, Cryptosporidium, Giardia, STEC, rotavirus
 Child care center attendance or employmentRotavirus, Cryptosporidium, Giardia, Shigella, STEC
 Recent antimicrobial therapyC. difficile, multidrug-resistant Salmonella
 Travel to resource-challenged countriesEscherichia coli (enteroaggregative, enterotoxigenic, enteroinvasive), Shigella, Typhi and nontyphoidal Salmonella, Campylobacter, Vibrio cholerae, Entamoeba histolytica, Giardia, Blastocystis, Cyclospora, Cystoisospora, Cryptosporidium
 Exposure to house pets with diarrheaCampylobacter, Yersinia
 Exposure to pig feces in certain parts of the worldBalantidium coli
 Contact with young poultry or reptilesNontyphoidal Salmonella
 Visiting a farm or petting zooSTEC, Cryptosporidium, Campylobacter
Exposure or condition
 Age groupRotavirus (6–18 months of age), nontyphoidal Salmonella (infants from birth to 3 months of age and adults >50 years with a history of atherosclerosis), Shigella (1–7 years of age), Campylobacter (young adults)
 Underlying immunocompromising conditionNontyphoidal Salmonella, Cryptosporidium, Campylobacter, Shigella, Yersinia
 Hemochromatosis or hemoglobinopathyY. enterocolitica, Salmonella
 AIDS, immunosuppressive therapiesCryptosporidium, Cyclospora, Cystoisospora, microsporidia, Mycobacterium avium–intercellulare complex, cytomegalovirus
 Anal-genital, oral-anal, or digital-anal contactShigella, Salmonella, Campylobacter, E. histolytica, Giardia lamblia, Cryptosporidium as well as sexually transmitted infections
Exposure or ConditionPathogen(s)
Foodborne
 Foodborne outbreaks in hotels, cruise ships, resorts, restaurants, catered eventsNorovirus, nontyphoidal Salmonella, Clostridium perfringens, Bacillus cereus, Staphylococcus aureus, Campylobacter spp, ETEC, STEC, Listeria, Shigella, Cyclospora cayetanensis, Cryptosporidium spp
 Consumption of unpasteurized milk or dairy productsSalmonella, Campylobacter, Yersinia enterocolitica, S. aureus toxin, Cryptosporidium, and STEC. Listeria is infrequently associated with diarrhea, Brucella (goat milk cheese), Mycobacterium bovis, Coxiella burnetii
 Consumption of raw or undercooked meat or poultrySTEC (beef), C. perfringens (beef, poultry), Salmonella (poultry), Campylobacter (poultry), Yersinia (pork, chitterlings), S. aureus (poultry), and Trichinella spp (pork, wild game meat)
 Consumption of fruits or unpasteurized fruit juices, vegetables, leafy greens, and sproutsSTEC, nontyphoidal Salmonella, Cyclospora, Cryptosporidium, norovirus, hepatitis A, and Listeria monocytogenes
 Consumption of undercooked eggsSalmonella, Shigella (egg salad)
 Consumption of raw shellfishVibrio species, norovirus, hepatitis A, Plesiomonas
Exposure or contact
 Swimming in or drinking untreated fresh waterCampylobacter, Cryptosporidium, Giardia, Shigella, Salmonella, STEC, Plesiomonas shigelloides
 Swimming in recreational water facility with treated waterCryptosporidium and other potentially waterborne pathogens when disinfectant concentrations are inadequately maintained
 Healthcare, long-term care, prison exposure, or employmentNorovirus, Clostridium difficile, Shigella, Cryptosporidium, Giardia, STEC, rotavirus
 Child care center attendance or employmentRotavirus, Cryptosporidium, Giardia, Shigella, STEC
 Recent antimicrobial therapyC. difficile, multidrug-resistant Salmonella
 Travel to resource-challenged countriesEscherichia coli (enteroaggregative, enterotoxigenic, enteroinvasive), Shigella, Typhi and nontyphoidal Salmonella, Campylobacter, Vibrio cholerae, Entamoeba histolytica, Giardia, Blastocystis, Cyclospora, Cystoisospora, Cryptosporidium
 Exposure to house pets with diarrheaCampylobacter, Yersinia
 Exposure to pig feces in certain parts of the worldBalantidium coli
 Contact with young poultry or reptilesNontyphoidal Salmonella
 Visiting a farm or petting zooSTEC, Cryptosporidium, Campylobacter
Exposure or condition
 Age groupRotavirus (6–18 months of age), nontyphoidal Salmonella (infants from birth to 3 months of age and adults >50 years with a history of atherosclerosis), Shigella (1–7 years of age), Campylobacter (young adults)
 Underlying immunocompromising conditionNontyphoidal Salmonella, Cryptosporidium, Campylobacter, Shigella, Yersinia
 Hemochromatosis or hemoglobinopathyY. enterocolitica, Salmonella
 AIDS, immunosuppressive therapiesCryptosporidium, Cyclospora, Cystoisospora, microsporidia, Mycobacterium avium–intercellulare complex, cytomegalovirus
 Anal-genital, oral-anal, or digital-anal contactShigella, Salmonella, Campylobacter, E. histolytica, Giardia lamblia, Cryptosporidium as well as sexually transmitted infections

Abbreviations: ETEC, enterotoxigenic Escherichia coli; STEC, Shiga toxin–producing Escherichia coli.

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