| Category/grade | Definition |
| Strength of recommendation | |
| A | Good evidence to support a recommendation for or against use |
| B | Moderate evidence to support a recommendation for or against use |
| C | Poor evidence to support a recommendation |
| Quality of evidence | |
| I | Evidence from ≥1 properly randomized, controlled trial |
| II | Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |
| Category/grade | Definition |
| Strength of recommendation | |
| A | Good evidence to support a recommendation for or against use |
| B | Moderate evidence to support a recommendation for or against use |
| C | Poor evidence to support a recommendation |
| Quality of evidence | |
| I | Evidence from ≥1 properly randomized, controlled trial |
| II | Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |
NOTE. Data are from the periodic health examination. Canadian Task Force on the Periodic Health Examination. Health Canada, 1979. Adapted and Reproduced with the permission of the Minister of Public Works and Government Services Canada, 2009 [32].
| Category/grade | Definition |
| Strength of recommendation | |
| A | Good evidence to support a recommendation for or against use |
| B | Moderate evidence to support a recommendation for or against use |
| C | Poor evidence to support a recommendation |
| Quality of evidence | |
| I | Evidence from ≥1 properly randomized, controlled trial |
| II | Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |
| Category/grade | Definition |
| Strength of recommendation | |
| A | Good evidence to support a recommendation for or against use |
| B | Moderate evidence to support a recommendation for or against use |
| C | Poor evidence to support a recommendation |
| Quality of evidence | |
| I | Evidence from ≥1 properly randomized, controlled trial |
| II | Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |
NOTE. Data are from the periodic health examination. Canadian Task Force on the Periodic Health Examination. Health Canada, 1979. Adapted and Reproduced with the permission of the Minister of Public Works and Government Services Canada, 2009 [32].
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