Measures of Treatment Completion and Adherence Stratified by Dosing Pattern
| Variable . | Overall (N = 190) . | Once Daily (n = 103) . | Twice Daily (n = 87) . |
|---|---|---|---|
| Treatment completion | 184 (97) | 100 (97) | 84 (97) |
| No. of days nonadherent to therapy | |||
| None (100% adherent) | 19 (10) | 12 (12) | 7 (8) |
| 1–4 (95% to <100% adherent) | 56 (29) | 36 (35) | 20 (23) |
| 5–8 (90% to <95% adherent) | 35 (18) | 20 (19) | 15 (17) |
| 9–17 (80% to <90% adherent) | 34 (18) | 17 (17) | 17 (20) |
| ≥18 (<80% adherent) | 46 (24) | 18 (17) | 28 (32) |
| Overall adherence, % (95% CI) | |||
| Patient report | 99 (97–100) | 99 (98–100) | 99 (96–100) |
| Blister pack, weekly | 98 (94–100) | 98 (94–100) | 98 (93–99) |
| Blister pack, daily | 92 (81–98) | 94 (88–98) | 88 (75–96) |
| Longest episode of nonadherence, days | |||
| 1 | 80 (42) | 44 (43) | 36 (41) |
| 2 | 39 (21) | 19 (18) | 20 (23) |
| 3 | 8 (4) | 3 (3) | 5 (6) |
| 4 | 11 (6) | 9 (9) | 2 (2) |
| 5 | 5 (3) | 2 (2) | 3 (3) |
| 6 | 3 (2) | 3 (3) | 0 (0) |
| ≥7 | 25 (13) | 11 (11) | 14 (16) |
| Variable . | Overall (N = 190) . | Once Daily (n = 103) . | Twice Daily (n = 87) . |
|---|---|---|---|
| Treatment completion | 184 (97) | 100 (97) | 84 (97) |
| No. of days nonadherent to therapy | |||
| None (100% adherent) | 19 (10) | 12 (12) | 7 (8) |
| 1–4 (95% to <100% adherent) | 56 (29) | 36 (35) | 20 (23) |
| 5–8 (90% to <95% adherent) | 35 (18) | 20 (19) | 15 (17) |
| 9–17 (80% to <90% adherent) | 34 (18) | 17 (17) | 17 (20) |
| ≥18 (<80% adherent) | 46 (24) | 18 (17) | 28 (32) |
| Overall adherence, % (95% CI) | |||
| Patient report | 99 (97–100) | 99 (98–100) | 99 (96–100) |
| Blister pack, weekly | 98 (94–100) | 98 (94–100) | 98 (93–99) |
| Blister pack, daily | 92 (81–98) | 94 (88–98) | 88 (75–96) |
| Longest episode of nonadherence, days | |||
| 1 | 80 (42) | 44 (43) | 36 (41) |
| 2 | 39 (21) | 19 (18) | 20 (23) |
| 3 | 8 (4) | 3 (3) | 5 (6) |
| 4 | 11 (6) | 9 (9) | 2 (2) |
| 5 | 5 (3) | 2 (2) | 3 (3) |
| 6 | 3 (2) | 3 (3) | 0 (0) |
| ≥7 | 25 (13) | 11 (11) | 14 (16) |
Data are presented as no. (%) unless otherwise indicated.
Abbreviation: CI, confidence interval.
Measures of Treatment Completion and Adherence Stratified by Dosing Pattern
| Variable . | Overall (N = 190) . | Once Daily (n = 103) . | Twice Daily (n = 87) . |
|---|---|---|---|
| Treatment completion | 184 (97) | 100 (97) | 84 (97) |
| No. of days nonadherent to therapy | |||
| None (100% adherent) | 19 (10) | 12 (12) | 7 (8) |
| 1–4 (95% to <100% adherent) | 56 (29) | 36 (35) | 20 (23) |
| 5–8 (90% to <95% adherent) | 35 (18) | 20 (19) | 15 (17) |
| 9–17 (80% to <90% adherent) | 34 (18) | 17 (17) | 17 (20) |
| ≥18 (<80% adherent) | 46 (24) | 18 (17) | 28 (32) |
| Overall adherence, % (95% CI) | |||
| Patient report | 99 (97–100) | 99 (98–100) | 99 (96–100) |
| Blister pack, weekly | 98 (94–100) | 98 (94–100) | 98 (93–99) |
| Blister pack, daily | 92 (81–98) | 94 (88–98) | 88 (75–96) |
| Longest episode of nonadherence, days | |||
| 1 | 80 (42) | 44 (43) | 36 (41) |
| 2 | 39 (21) | 19 (18) | 20 (23) |
| 3 | 8 (4) | 3 (3) | 5 (6) |
| 4 | 11 (6) | 9 (9) | 2 (2) |
| 5 | 5 (3) | 2 (2) | 3 (3) |
| 6 | 3 (2) | 3 (3) | 0 (0) |
| ≥7 | 25 (13) | 11 (11) | 14 (16) |
| Variable . | Overall (N = 190) . | Once Daily (n = 103) . | Twice Daily (n = 87) . |
|---|---|---|---|
| Treatment completion | 184 (97) | 100 (97) | 84 (97) |
| No. of days nonadherent to therapy | |||
| None (100% adherent) | 19 (10) | 12 (12) | 7 (8) |
| 1–4 (95% to <100% adherent) | 56 (29) | 36 (35) | 20 (23) |
| 5–8 (90% to <95% adherent) | 35 (18) | 20 (19) | 15 (17) |
| 9–17 (80% to <90% adherent) | 34 (18) | 17 (17) | 17 (20) |
| ≥18 (<80% adherent) | 46 (24) | 18 (17) | 28 (32) |
| Overall adherence, % (95% CI) | |||
| Patient report | 99 (97–100) | 99 (98–100) | 99 (96–100) |
| Blister pack, weekly | 98 (94–100) | 98 (94–100) | 98 (93–99) |
| Blister pack, daily | 92 (81–98) | 94 (88–98) | 88 (75–96) |
| Longest episode of nonadherence, days | |||
| 1 | 80 (42) | 44 (43) | 36 (41) |
| 2 | 39 (21) | 19 (18) | 20 (23) |
| 3 | 8 (4) | 3 (3) | 5 (6) |
| 4 | 11 (6) | 9 (9) | 2 (2) |
| 5 | 5 (3) | 2 (2) | 3 (3) |
| 6 | 3 (2) | 3 (3) | 0 (0) |
| ≥7 | 25 (13) | 11 (11) | 14 (16) |
Data are presented as no. (%) unless otherwise indicated.
Abbreviation: CI, confidence interval.
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