Table 3. Open in new tab Effect of PCNL...

References

Type of study

Patients, n

Method of assessment

Time points of assessment

Renal function

Ünsal et al. [27]

RCT (three different dilatation techniques of percutaneous track)

Tc-99 QDMSA^a
sCr

Preoperatively
3–6 months post-operatively

No difference between groups and with baseline

Moosanejad et al. [28]

RCT (postop ureteral stenting or not)

sCr

Preoperatively
24-h post-operatively

No difference between groups

Chatham et al. [29]

Prospective observational

TC-99 AG3^b
sCr

Preoperatively
2.22-days post-operatively

Stable or improved

Moskovitz et al. [30]

Prospective observational

Tc-99 QDMSA^a

Preoperatively
1-month post-operatively
5- to 24-months post-operatively

Stable

Kiliç et al. [31]

Prospective observational

CDUS

Preoperatively
1-day post-operatively
3-, 6- and 12-months post-operatively

Stable

Bayrak et al. [32]

Prospective observational

sCr
eCrCl (Cockroft–Gault)

Preoperatively
72-h post-operatively

Improved (P < 0.001)

Su et al. [33]

Prospective observational

eGFR (MDRD)

Preoperatively
2- and 24-h post-operatively
6-months post-operatively

Stable or improved (P < 0.001)

Handa et al. [34]

Retrospective observational

196

sCr

Pre-op
24-h post-op

Decreased (P < 0.001)

Hegarty and Desai[35]

Retrospective observational

sCr
CrCl

Single tract PCNL: stable
Multitract PCNL: decreased (P < 0.05)

Bilen et al. [36]

Retrospective observational

185

eGFR (MDRD)

Preoperatively
Before discharge
3-months post-operatively

Improved (P = 0.02)

Nouralizadeh et al. [37]

Retrospective observational

eCrCl (Cockroft–Gault)

Preoperatively
6-, 24-, 48-, and 72-h post-operatively

Preoperatively versus 72 h: stable
Preoperatively versus 24 and 48 h: decreased (P < 0.05)

Bucuras et al. [38]

Retrospective observational

189

sCr

Preoperatively
24-h postoperatively

Stable

El-Tabey et al. [39]

Retrospective observational

200

eCrCl (Cockroft–Gault)

Improved (P < 0.001)

Table 3.

Open in new tab

Effect of PCNL on renal function indexes

References	Type of study	Patients, n	Method of assessment	Time points of assessment	Renal function
Ünsal et al. [27]	RCT (three different dilatation techniques of percutaneous track)	50	Tc-99 QDMSA^a sCr	Preoperatively 3–6 months post-operatively	No difference between groups and with baseline
Moosanejad et al. [28]	RCT (postop ureteral stenting or not)	84	sCr	Preoperatively 24-h post-operatively	No difference between groups
Chatham et al. [29]	Prospective observational	19	TC-99 AG3^b sCr	Preoperatively 2.22-days post-operatively	Stable or improved
Moskovitz et al. [30]	Prospective observational	87	Tc-99 QDMSA^a	Preoperatively 1-month post-operatively 5- to 24-months post-operatively	Stable
Kiliç et al. [31]	Prospective observational	24	CDUS	Preoperatively 1-day post-operatively 3-, 6- and 12-months post-operatively	Stable
Bayrak et al. [32]	Prospective observational	80	sCr eCrCl (Cockroft–Gault)	Preoperatively 72-h post-operatively	Improved (P < 0.001)
Su et al. [33]	Prospective observational	44	eGFR (MDRD)	Preoperatively 2- and 24-h post-operatively 6-months post-operatively	Stable or improved (P < 0.001)
Handa et al. [34]	Retrospective observational	196	sCr	Pre-op 24-h post-op	Decreased (P < 0.001)
Hegarty and Desai[35]	Retrospective observational	20	sCr CrCl	NR	Single tract PCNL: stable Multitract PCNL: decreased (P < 0.05)
Bilen et al. [36]	Retrospective observational	185	eGFR (MDRD)	Preoperatively Before discharge 3-months post-operatively	Improved (P = 0.02)
Nouralizadeh et al. [37]	Retrospective observational	94	eCrCl (Cockroft–Gault)	Preoperatively 6-, 24-, 48-, and 72-h post-operatively	Preoperatively versus 72 h: stable Preoperatively versus 24 and 48 h: decreased (P < 0.05)
Bucuras et al. [38]	Retrospective observational	189	sCr	Preoperatively 24-h postoperatively	Stable
El-Tabey et al. [39]	Retrospective observational	200	eCrCl (Cockroft–Gault)	NR	Improved (P < 0.001)

References	Type of study	Patients, n	Method of assessment	Time points of assessment	Renal function
Ünsal et al. [27]	RCT (three different dilatation techniques of percutaneous track)	50	Tc-99 QDMSA^a sCr	Preoperatively 3–6 months post-operatively	No difference between groups and with baseline
Moosanejad et al. [28]	RCT (postop ureteral stenting or not)	84	sCr	Preoperatively 24-h post-operatively	No difference between groups
Chatham et al. [29]	Prospective observational	19	TC-99 AG3^b sCr	Preoperatively 2.22-days post-operatively	Stable or improved
Moskovitz et al. [30]	Prospective observational	87	Tc-99 QDMSA^a	Preoperatively 1-month post-operatively 5- to 24-months post-operatively	Stable
Kiliç et al. [31]	Prospective observational	24	CDUS	Preoperatively 1-day post-operatively 3-, 6- and 12-months post-operatively	Stable
Bayrak et al. [32]	Prospective observational	80	sCr eCrCl (Cockroft–Gault)	Preoperatively 72-h post-operatively	Improved (P < 0.001)
Su et al. [33]	Prospective observational	44	eGFR (MDRD)	Preoperatively 2- and 24-h post-operatively 6-months post-operatively	Stable or improved (P < 0.001)
Handa et al. [34]	Retrospective observational	196	sCr	Pre-op 24-h post-op	Decreased (P < 0.001)
Hegarty and Desai[35]	Retrospective observational	20	sCr CrCl	NR	Single tract PCNL: stable Multitract PCNL: decreased (P < 0.05)
Bilen et al. [36]	Retrospective observational	185	eGFR (MDRD)	Preoperatively Before discharge 3-months post-operatively	Improved (P = 0.02)
Nouralizadeh et al. [37]	Retrospective observational	94	eCrCl (Cockroft–Gault)	Preoperatively 6-, 24-, 48-, and 72-h post-operatively	Preoperatively versus 72 h: stable Preoperatively versus 24 and 48 h: decreased (P < 0.05)
Bucuras et al. [38]	Retrospective observational	189	sCr	Preoperatively 24-h postoperatively	Stable
El-Tabey et al. [39]	Retrospective observational	200	eCrCl (Cockroft–Gault)	NR	Improved (P < 0.001)

Tc-99 QDMSA was used for assessment of renal defects, differential function and GFR (Gates method).

Tc-99 MAG3 was used for measurement of differential function.

Tc-99 QDMSA, quantitative SPECT of technetium-99 dimercaptosuccinic acid; Tc-99 MAG3, technetium-99m mercaptoacetyltriglycine; CDUS, colour Doppler ultrasonography; eCrCl, estimated creatinine clearance.

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