Suggestions for Hyaluronidase Availability and Use in Advent of Suspected Visual and Associated Cutaneous Impairment
| Hyaluronidase . | Expectation . |
|---|---|
| Clinic handling | Every clinic should have hyaluronidase on hand and be able to inject this agent |
| Local use | If visual loss is diagnosed, clinician should consider injecting high-dose hyaluronidase at area where injection appeared to induce visual loss and to area of any suspected cutaneous vascular compromise |
| Regional use | If clinician is comfortable with technique, inject high-dose hyaluronidase at supraorbital, supratrochlear, or other ophthalmic artery branches |
| Retrobulbar and peribulbar use | Only if clinician is certain of diagnosis and has requisite knowledge and skill should retrobulbar or peribulbar injection be attempted |
| Hyaluronidase . | Expectation . |
|---|---|
| Clinic handling | Every clinic should have hyaluronidase on hand and be able to inject this agent |
| Local use | If visual loss is diagnosed, clinician should consider injecting high-dose hyaluronidase at area where injection appeared to induce visual loss and to area of any suspected cutaneous vascular compromise |
| Regional use | If clinician is comfortable with technique, inject high-dose hyaluronidase at supraorbital, supratrochlear, or other ophthalmic artery branches |
| Retrobulbar and peribulbar use | Only if clinician is certain of diagnosis and has requisite knowledge and skill should retrobulbar or peribulbar injection be attempted |
Suggestions for Hyaluronidase Availability and Use in Advent of Suspected Visual and Associated Cutaneous Impairment
| Hyaluronidase . | Expectation . |
|---|---|
| Clinic handling | Every clinic should have hyaluronidase on hand and be able to inject this agent |
| Local use | If visual loss is diagnosed, clinician should consider injecting high-dose hyaluronidase at area where injection appeared to induce visual loss and to area of any suspected cutaneous vascular compromise |
| Regional use | If clinician is comfortable with technique, inject high-dose hyaluronidase at supraorbital, supratrochlear, or other ophthalmic artery branches |
| Retrobulbar and peribulbar use | Only if clinician is certain of diagnosis and has requisite knowledge and skill should retrobulbar or peribulbar injection be attempted |
| Hyaluronidase . | Expectation . |
|---|---|
| Clinic handling | Every clinic should have hyaluronidase on hand and be able to inject this agent |
| Local use | If visual loss is diagnosed, clinician should consider injecting high-dose hyaluronidase at area where injection appeared to induce visual loss and to area of any suspected cutaneous vascular compromise |
| Regional use | If clinician is comfortable with technique, inject high-dose hyaluronidase at supraorbital, supratrochlear, or other ophthalmic artery branches |
| Retrobulbar and peribulbar use | Only if clinician is certain of diagnosis and has requisite knowledge and skill should retrobulbar or peribulbar injection be attempted |
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