Characteristics of General Clinic Populationa Patients by Most Recent QuantiFERON-Gold In-Tube Result, New York City, November 2009–December 2011 (n = 18 481 Patients)
| Characteristic . | Total n (%) . | Positive n (%) . | Negative n (%) . | Indeterminate n (%) . | Unadjusted ORb (95% CI) . | Adjusted ORb,c (95% CI) . |
|---|---|---|---|---|---|---|
| Total persons | 18 481 | 2644 (14) | 15 749 (85) | 88 (<1) | – | – |
| Age group | ||||||
| 0–4 years | 66 (0) | 2 (3) | 64 (97) | 0 (0) | .23 (.60, .92)* | .16 (.04, .67)* |
| 5–18 years | 7052 (38) | 788 (11) | 6250 (89) | 14 (0) | .91 (.82, 1.00) | .49 (.44, .55)* |
| 19–44 years | 7245 (39) | 883 (12) | 6320 (87) | 42 (1) | Ref | Ref |
| 45–64 years | 3627 (20) | 764 (21) | 2834 (78) | 29 (1) | 1.92 (1.73, 2.14)* | 1.92 (1.71, 2.16)* |
| ≥65 years | 491 (3) | 207 (42) | 281 (57) | 3 (1) | 5.24 (4.33, 6.37)* | 3.84 (3.12, 4.72)* |
| Sex | ||||||
| Male | 10 998 (60) | 1660 (15) | 9280 (84) | 58 (1) | Ref | Ref |
| Female | 7483 (40) | 984 (13) | 6469 (86) | 30 (1) | .85 (.78, .93)* | .87 (.80, .95)* |
| Race/Ethnicity | ||||||
| Non-Hispanic white | 2023 (11) | 209 (10) | 1809 (90) | 5 (0) | Ref | Ref |
| Non-Hispanic black | 6602 (36) | 839 (13) | 5719 (86) | 44 (1) | 1.26 (1.08, 1.48)* | 1.43 (1.20, 1.69)* |
| Hispanic | 6660 (36) | 994 (15) | 5641 (85) | 25 (0) | 1.52 (1.30, 1.78)* | 1.45 (1.22, 1.72)* |
| Asian | 2242 (12) | 464 (21) | 1767 (79) | 11 (0) | 2.27 (1.90, 2.70)* | 1.42 (1.16, 1.73)* |
| Other/Unknown | 954 (5) | 138 (15) | 813 (85) | 3 (0) | 1.47 (1.17, 1.85)* | 1.35 (1.06, 1.73)* |
| United States-bornd | 8689 (47) | 751 (9) | 7884 (91) | 54 (1) | .39 (.36, .43)* | .57 (.47, .69)* |
| Foreign-born | 9792 (53) | 1893 (19) | 7865 (80) | 34 (1) | Ref | Ref |
| Top 5 countries of birth | ||||||
| Dominican Republic | 2287 (23) | 386 (17) | 1896 (83) | 5 (0) | – | – |
| China | 665 (7) | 148 (22) | 515 (78) | 2 (0) | – | – |
| Haiti | 612 (6) | 136 (22) | 475 (78) | 1 (0) | – | – |
| Ecuador | 545 (6) | 115 (21) | 429 (79) | 1 (0) | – | – |
| Jamaica | 514 (5) | 54 (11) | 459 (89) | 1 (0) | – | – |
| Years in the United States | ||||||
| <2 | 6435 (66) | 1135 (18) | 5282 (83) | 18 (0) | Ref | – |
| 2–5 | 521 (5) | 126 (24) | 392 (75) | 3 (1) | 1.49 (1.21, 1.84)* | – |
| ≥5 | 2836 (29) | 632 (22) | 2191 (77) | 13 (1) | 1.34 (1.20, 1.49)* | – |
| Median (IQR) | 1 (0, 10) | 0 (0, 7) | 1 (0, 15) | <.0001 | – | |
| TB incidence in country of birthe | ||||||
| High (≥140 cases per 100 000) | 2612 (14) | 629 (24) | 1968 (75) | 15 (1) | 3.17 (2.83, 3.55)* | 3.10 (2.52, 3.81)* |
| Medium (30–139) | 5915 (32) | 1110 (19) | 4787 (81) | 18 (0) | 2.31 (2.10, 2.54)* | 1.96 (1.61, 2.40)* |
| Low (0–29) | 9913 (54) | 895 (9) | 8963 (90) | 55 (1) | Ref | Ref |
| HIV status | ||||||
| Uninfected | 3207 (17) | 789 (25) | 2408 (75) | 10 (0) | Ref | – |
| Infected | 17 (0) | 2 (12) | 14 (82) | 1 (6) | .41 (.09, 1.79) | – |
| Unknown | 15 257 (83) | 1853 (12) | 13 327 (87) | 77 (1) | .42 (.39, .47)* | – |
| TB risk factors | ||||||
| History of injection drug use | 354 (2) | 64 (18) | 286 (81) | 4 (1) | 1.33 (1.01, 1.75)* | 1.56 (1.17, 2.09)* |
| Spent time in high-risk settingf | 5741 (31) | 786 (14) | 4910 (85) | 45 (1) | .93 (.85, 1.02) | – |
| Homeless at testing | 2742 (15) | 414 (15) | 2315 (84) | 13 (1) | 1.06 (.95, 1.19) | – |
| Spent >1 month outside the United States | 1854 (10) | 295 (16) | 1552 (84) | 7 (0) | 1.15 (1.01, 1.31)* | 1.02 (.88, 1.17) |
| Ever smoked tobacco | 3826 (21) | 519 (13) | 3285 (86) | 22 (1) | .93 (.84, 1.03) | – |
| Characteristic . | Total n (%) . | Positive n (%) . | Negative n (%) . | Indeterminate n (%) . | Unadjusted ORb (95% CI) . | Adjusted ORb,c (95% CI) . |
|---|---|---|---|---|---|---|
| Total persons | 18 481 | 2644 (14) | 15 749 (85) | 88 (<1) | – | – |
| Age group | ||||||
| 0–4 years | 66 (0) | 2 (3) | 64 (97) | 0 (0) | .23 (.60, .92)* | .16 (.04, .67)* |
| 5–18 years | 7052 (38) | 788 (11) | 6250 (89) | 14 (0) | .91 (.82, 1.00) | .49 (.44, .55)* |
| 19–44 years | 7245 (39) | 883 (12) | 6320 (87) | 42 (1) | Ref | Ref |
| 45–64 years | 3627 (20) | 764 (21) | 2834 (78) | 29 (1) | 1.92 (1.73, 2.14)* | 1.92 (1.71, 2.16)* |
| ≥65 years | 491 (3) | 207 (42) | 281 (57) | 3 (1) | 5.24 (4.33, 6.37)* | 3.84 (3.12, 4.72)* |
| Sex | ||||||
| Male | 10 998 (60) | 1660 (15) | 9280 (84) | 58 (1) | Ref | Ref |
| Female | 7483 (40) | 984 (13) | 6469 (86) | 30 (1) | .85 (.78, .93)* | .87 (.80, .95)* |
| Race/Ethnicity | ||||||
| Non-Hispanic white | 2023 (11) | 209 (10) | 1809 (90) | 5 (0) | Ref | Ref |
| Non-Hispanic black | 6602 (36) | 839 (13) | 5719 (86) | 44 (1) | 1.26 (1.08, 1.48)* | 1.43 (1.20, 1.69)* |
| Hispanic | 6660 (36) | 994 (15) | 5641 (85) | 25 (0) | 1.52 (1.30, 1.78)* | 1.45 (1.22, 1.72)* |
| Asian | 2242 (12) | 464 (21) | 1767 (79) | 11 (0) | 2.27 (1.90, 2.70)* | 1.42 (1.16, 1.73)* |
| Other/Unknown | 954 (5) | 138 (15) | 813 (85) | 3 (0) | 1.47 (1.17, 1.85)* | 1.35 (1.06, 1.73)* |
| United States-bornd | 8689 (47) | 751 (9) | 7884 (91) | 54 (1) | .39 (.36, .43)* | .57 (.47, .69)* |
| Foreign-born | 9792 (53) | 1893 (19) | 7865 (80) | 34 (1) | Ref | Ref |
| Top 5 countries of birth | ||||||
| Dominican Republic | 2287 (23) | 386 (17) | 1896 (83) | 5 (0) | – | – |
| China | 665 (7) | 148 (22) | 515 (78) | 2 (0) | – | – |
| Haiti | 612 (6) | 136 (22) | 475 (78) | 1 (0) | – | – |
| Ecuador | 545 (6) | 115 (21) | 429 (79) | 1 (0) | – | – |
| Jamaica | 514 (5) | 54 (11) | 459 (89) | 1 (0) | – | – |
| Years in the United States | ||||||
| <2 | 6435 (66) | 1135 (18) | 5282 (83) | 18 (0) | Ref | – |
| 2–5 | 521 (5) | 126 (24) | 392 (75) | 3 (1) | 1.49 (1.21, 1.84)* | – |
| ≥5 | 2836 (29) | 632 (22) | 2191 (77) | 13 (1) | 1.34 (1.20, 1.49)* | – |
| Median (IQR) | 1 (0, 10) | 0 (0, 7) | 1 (0, 15) | <.0001 | – | |
| TB incidence in country of birthe | ||||||
| High (≥140 cases per 100 000) | 2612 (14) | 629 (24) | 1968 (75) | 15 (1) | 3.17 (2.83, 3.55)* | 3.10 (2.52, 3.81)* |
| Medium (30–139) | 5915 (32) | 1110 (19) | 4787 (81) | 18 (0) | 2.31 (2.10, 2.54)* | 1.96 (1.61, 2.40)* |
| Low (0–29) | 9913 (54) | 895 (9) | 8963 (90) | 55 (1) | Ref | Ref |
| HIV status | ||||||
| Uninfected | 3207 (17) | 789 (25) | 2408 (75) | 10 (0) | Ref | – |
| Infected | 17 (0) | 2 (12) | 14 (82) | 1 (6) | .41 (.09, 1.79) | – |
| Unknown | 15 257 (83) | 1853 (12) | 13 327 (87) | 77 (1) | .42 (.39, .47)* | – |
| TB risk factors | ||||||
| History of injection drug use | 354 (2) | 64 (18) | 286 (81) | 4 (1) | 1.33 (1.01, 1.75)* | 1.56 (1.17, 2.09)* |
| Spent time in high-risk settingf | 5741 (31) | 786 (14) | 4910 (85) | 45 (1) | .93 (.85, 1.02) | – |
| Homeless at testing | 2742 (15) | 414 (15) | 2315 (84) | 13 (1) | 1.06 (.95, 1.19) | – |
| Spent >1 month outside the United States | 1854 (10) | 295 (16) | 1552 (84) | 7 (0) | 1.15 (1.01, 1.31)* | 1.02 (.88, 1.17) |
| Ever smoked tobacco | 3826 (21) | 519 (13) | 3285 (86) | 22 (1) | .93 (.84, 1.03) | – |
Abbreviations: CI, confidence intervals; HIV, human immunodeficiency virus; IQR, interquartile range; OR, odds ratio; Ref, Reference; TB, tuberculosis.
a General clinic population patients were those who were neither a case nor a contact at the time of testing.
b Odds ratios compare patients with a positive test to those with a negative or indeterminate test.
c Adjusted odds ratios were calculated adjusting for all variables where an OR and 95% CI are reported.
d United States-born includes patients born in the United States, Puerto Rico, and other United States territories and outlying areas.
e Tuberculosis incidence categories are based on tertiles using World Health Organization national incidence estimates.
f High-risk settings include jails, prisons, homeless shelters, and drug treatment facilities.
* Indicates a significant result with P < .05.
Characteristics of General Clinic Populationa Patients by Most Recent QuantiFERON-Gold In-Tube Result, New York City, November 2009–December 2011 (n = 18 481 Patients)
| Characteristic . | Total n (%) . | Positive n (%) . | Negative n (%) . | Indeterminate n (%) . | Unadjusted ORb (95% CI) . | Adjusted ORb,c (95% CI) . |
|---|---|---|---|---|---|---|
| Total persons | 18 481 | 2644 (14) | 15 749 (85) | 88 (<1) | – | – |
| Age group | ||||||
| 0–4 years | 66 (0) | 2 (3) | 64 (97) | 0 (0) | .23 (.60, .92)* | .16 (.04, .67)* |
| 5–18 years | 7052 (38) | 788 (11) | 6250 (89) | 14 (0) | .91 (.82, 1.00) | .49 (.44, .55)* |
| 19–44 years | 7245 (39) | 883 (12) | 6320 (87) | 42 (1) | Ref | Ref |
| 45–64 years | 3627 (20) | 764 (21) | 2834 (78) | 29 (1) | 1.92 (1.73, 2.14)* | 1.92 (1.71, 2.16)* |
| ≥65 years | 491 (3) | 207 (42) | 281 (57) | 3 (1) | 5.24 (4.33, 6.37)* | 3.84 (3.12, 4.72)* |
| Sex | ||||||
| Male | 10 998 (60) | 1660 (15) | 9280 (84) | 58 (1) | Ref | Ref |
| Female | 7483 (40) | 984 (13) | 6469 (86) | 30 (1) | .85 (.78, .93)* | .87 (.80, .95)* |
| Race/Ethnicity | ||||||
| Non-Hispanic white | 2023 (11) | 209 (10) | 1809 (90) | 5 (0) | Ref | Ref |
| Non-Hispanic black | 6602 (36) | 839 (13) | 5719 (86) | 44 (1) | 1.26 (1.08, 1.48)* | 1.43 (1.20, 1.69)* |
| Hispanic | 6660 (36) | 994 (15) | 5641 (85) | 25 (0) | 1.52 (1.30, 1.78)* | 1.45 (1.22, 1.72)* |
| Asian | 2242 (12) | 464 (21) | 1767 (79) | 11 (0) | 2.27 (1.90, 2.70)* | 1.42 (1.16, 1.73)* |
| Other/Unknown | 954 (5) | 138 (15) | 813 (85) | 3 (0) | 1.47 (1.17, 1.85)* | 1.35 (1.06, 1.73)* |
| United States-bornd | 8689 (47) | 751 (9) | 7884 (91) | 54 (1) | .39 (.36, .43)* | .57 (.47, .69)* |
| Foreign-born | 9792 (53) | 1893 (19) | 7865 (80) | 34 (1) | Ref | Ref |
| Top 5 countries of birth | ||||||
| Dominican Republic | 2287 (23) | 386 (17) | 1896 (83) | 5 (0) | – | – |
| China | 665 (7) | 148 (22) | 515 (78) | 2 (0) | – | – |
| Haiti | 612 (6) | 136 (22) | 475 (78) | 1 (0) | – | – |
| Ecuador | 545 (6) | 115 (21) | 429 (79) | 1 (0) | – | – |
| Jamaica | 514 (5) | 54 (11) | 459 (89) | 1 (0) | – | – |
| Years in the United States | ||||||
| <2 | 6435 (66) | 1135 (18) | 5282 (83) | 18 (0) | Ref | – |
| 2–5 | 521 (5) | 126 (24) | 392 (75) | 3 (1) | 1.49 (1.21, 1.84)* | – |
| ≥5 | 2836 (29) | 632 (22) | 2191 (77) | 13 (1) | 1.34 (1.20, 1.49)* | – |
| Median (IQR) | 1 (0, 10) | 0 (0, 7) | 1 (0, 15) | <.0001 | – | |
| TB incidence in country of birthe | ||||||
| High (≥140 cases per 100 000) | 2612 (14) | 629 (24) | 1968 (75) | 15 (1) | 3.17 (2.83, 3.55)* | 3.10 (2.52, 3.81)* |
| Medium (30–139) | 5915 (32) | 1110 (19) | 4787 (81) | 18 (0) | 2.31 (2.10, 2.54)* | 1.96 (1.61, 2.40)* |
| Low (0–29) | 9913 (54) | 895 (9) | 8963 (90) | 55 (1) | Ref | Ref |
| HIV status | ||||||
| Uninfected | 3207 (17) | 789 (25) | 2408 (75) | 10 (0) | Ref | – |
| Infected | 17 (0) | 2 (12) | 14 (82) | 1 (6) | .41 (.09, 1.79) | – |
| Unknown | 15 257 (83) | 1853 (12) | 13 327 (87) | 77 (1) | .42 (.39, .47)* | – |
| TB risk factors | ||||||
| History of injection drug use | 354 (2) | 64 (18) | 286 (81) | 4 (1) | 1.33 (1.01, 1.75)* | 1.56 (1.17, 2.09)* |
| Spent time in high-risk settingf | 5741 (31) | 786 (14) | 4910 (85) | 45 (1) | .93 (.85, 1.02) | – |
| Homeless at testing | 2742 (15) | 414 (15) | 2315 (84) | 13 (1) | 1.06 (.95, 1.19) | – |
| Spent >1 month outside the United States | 1854 (10) | 295 (16) | 1552 (84) | 7 (0) | 1.15 (1.01, 1.31)* | 1.02 (.88, 1.17) |
| Ever smoked tobacco | 3826 (21) | 519 (13) | 3285 (86) | 22 (1) | .93 (.84, 1.03) | – |
| Characteristic . | Total n (%) . | Positive n (%) . | Negative n (%) . | Indeterminate n (%) . | Unadjusted ORb (95% CI) . | Adjusted ORb,c (95% CI) . |
|---|---|---|---|---|---|---|
| Total persons | 18 481 | 2644 (14) | 15 749 (85) | 88 (<1) | – | – |
| Age group | ||||||
| 0–4 years | 66 (0) | 2 (3) | 64 (97) | 0 (0) | .23 (.60, .92)* | .16 (.04, .67)* |
| 5–18 years | 7052 (38) | 788 (11) | 6250 (89) | 14 (0) | .91 (.82, 1.00) | .49 (.44, .55)* |
| 19–44 years | 7245 (39) | 883 (12) | 6320 (87) | 42 (1) | Ref | Ref |
| 45–64 years | 3627 (20) | 764 (21) | 2834 (78) | 29 (1) | 1.92 (1.73, 2.14)* | 1.92 (1.71, 2.16)* |
| ≥65 years | 491 (3) | 207 (42) | 281 (57) | 3 (1) | 5.24 (4.33, 6.37)* | 3.84 (3.12, 4.72)* |
| Sex | ||||||
| Male | 10 998 (60) | 1660 (15) | 9280 (84) | 58 (1) | Ref | Ref |
| Female | 7483 (40) | 984 (13) | 6469 (86) | 30 (1) | .85 (.78, .93)* | .87 (.80, .95)* |
| Race/Ethnicity | ||||||
| Non-Hispanic white | 2023 (11) | 209 (10) | 1809 (90) | 5 (0) | Ref | Ref |
| Non-Hispanic black | 6602 (36) | 839 (13) | 5719 (86) | 44 (1) | 1.26 (1.08, 1.48)* | 1.43 (1.20, 1.69)* |
| Hispanic | 6660 (36) | 994 (15) | 5641 (85) | 25 (0) | 1.52 (1.30, 1.78)* | 1.45 (1.22, 1.72)* |
| Asian | 2242 (12) | 464 (21) | 1767 (79) | 11 (0) | 2.27 (1.90, 2.70)* | 1.42 (1.16, 1.73)* |
| Other/Unknown | 954 (5) | 138 (15) | 813 (85) | 3 (0) | 1.47 (1.17, 1.85)* | 1.35 (1.06, 1.73)* |
| United States-bornd | 8689 (47) | 751 (9) | 7884 (91) | 54 (1) | .39 (.36, .43)* | .57 (.47, .69)* |
| Foreign-born | 9792 (53) | 1893 (19) | 7865 (80) | 34 (1) | Ref | Ref |
| Top 5 countries of birth | ||||||
| Dominican Republic | 2287 (23) | 386 (17) | 1896 (83) | 5 (0) | – | – |
| China | 665 (7) | 148 (22) | 515 (78) | 2 (0) | – | – |
| Haiti | 612 (6) | 136 (22) | 475 (78) | 1 (0) | – | – |
| Ecuador | 545 (6) | 115 (21) | 429 (79) | 1 (0) | – | – |
| Jamaica | 514 (5) | 54 (11) | 459 (89) | 1 (0) | – | – |
| Years in the United States | ||||||
| <2 | 6435 (66) | 1135 (18) | 5282 (83) | 18 (0) | Ref | – |
| 2–5 | 521 (5) | 126 (24) | 392 (75) | 3 (1) | 1.49 (1.21, 1.84)* | – |
| ≥5 | 2836 (29) | 632 (22) | 2191 (77) | 13 (1) | 1.34 (1.20, 1.49)* | – |
| Median (IQR) | 1 (0, 10) | 0 (0, 7) | 1 (0, 15) | <.0001 | – | |
| TB incidence in country of birthe | ||||||
| High (≥140 cases per 100 000) | 2612 (14) | 629 (24) | 1968 (75) | 15 (1) | 3.17 (2.83, 3.55)* | 3.10 (2.52, 3.81)* |
| Medium (30–139) | 5915 (32) | 1110 (19) | 4787 (81) | 18 (0) | 2.31 (2.10, 2.54)* | 1.96 (1.61, 2.40)* |
| Low (0–29) | 9913 (54) | 895 (9) | 8963 (90) | 55 (1) | Ref | Ref |
| HIV status | ||||||
| Uninfected | 3207 (17) | 789 (25) | 2408 (75) | 10 (0) | Ref | – |
| Infected | 17 (0) | 2 (12) | 14 (82) | 1 (6) | .41 (.09, 1.79) | – |
| Unknown | 15 257 (83) | 1853 (12) | 13 327 (87) | 77 (1) | .42 (.39, .47)* | – |
| TB risk factors | ||||||
| History of injection drug use | 354 (2) | 64 (18) | 286 (81) | 4 (1) | 1.33 (1.01, 1.75)* | 1.56 (1.17, 2.09)* |
| Spent time in high-risk settingf | 5741 (31) | 786 (14) | 4910 (85) | 45 (1) | .93 (.85, 1.02) | – |
| Homeless at testing | 2742 (15) | 414 (15) | 2315 (84) | 13 (1) | 1.06 (.95, 1.19) | – |
| Spent >1 month outside the United States | 1854 (10) | 295 (16) | 1552 (84) | 7 (0) | 1.15 (1.01, 1.31)* | 1.02 (.88, 1.17) |
| Ever smoked tobacco | 3826 (21) | 519 (13) | 3285 (86) | 22 (1) | .93 (.84, 1.03) | – |
Abbreviations: CI, confidence intervals; HIV, human immunodeficiency virus; IQR, interquartile range; OR, odds ratio; Ref, Reference; TB, tuberculosis.
a General clinic population patients were those who were neither a case nor a contact at the time of testing.
b Odds ratios compare patients with a positive test to those with a negative or indeterminate test.
c Adjusted odds ratios were calculated adjusting for all variables where an OR and 95% CI are reported.
d United States-born includes patients born in the United States, Puerto Rico, and other United States territories and outlying areas.
e Tuberculosis incidence categories are based on tertiles using World Health Organization national incidence estimates.
f High-risk settings include jails, prisons, homeless shelters, and drug treatment facilities.
* Indicates a significant result with P < .05.
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