Table 3.

Univariable and Multivariable Predictors of Bronchiectasisa

Univariable Predictors
Multivariable Predictors
RR95% CIP ValueRR95% CIP Value
HTLV-1 Studies
 WB3.792.23–6.42.0001.841.19–2.84.006
 Ab titerb1.181.05–1.32.006
 PVLc1.211.08–1.36.001
Eosinophiliad1.961.21–3.19.006
Strongyloidese
 Positive2.231.31–3.79.0031.691.13–2.53.011
 Equivocal2.561.53–4.28.0001.831.18–2.82.006
Skin Infections
 Childhoodf3.772.36–6.03.0001.621.07–2.44.022
 Adulthoodf1.861.24–2.78.003
 Scabies1.741.04–2.92.036
IDH2.091.63–2.68.000
HTLV-1-associated conditionsg2.241.71–2.94.000
Haemophilus influenzaeh1.091.03–1.14.001
Alcoholi0.630.40–0.97.037
Univariable Predictors
Multivariable Predictors
RR95% CIP ValueRR95% CIP Value
HTLV-1 Studies
 WB3.792.23–6.42.0001.841.19–2.84.006
 Ab titerb1.181.05–1.32.006
 PVLc1.211.08–1.36.001
Eosinophiliad1.961.21–3.19.006
Strongyloidese
 Positive2.231.31–3.79.0031.691.13–2.53.011
 Equivocal2.561.53–4.28.0001.831.18–2.82.006
Skin Infections
 Childhoodf3.772.36–6.03.0001.621.07–2.44.022
 Adulthoodf1.861.24–2.78.003
 Scabies1.741.04–2.92.036
IDH2.091.63–2.68.000
HTLV-1-associated conditionsg2.241.71–2.94.000
Haemophilus influenzaeh1.091.03–1.14.001
Alcoholi0.630.40–0.97.037

Abbreviations: Ab, HTLV-1 antibody titer; CI, confidence interval; HTLV-1, human T-lymphotropic virus type 1; IDH, HTLV-1-associated infective dermatitis; RR, relative risk; PVL, proviral load; WB, Western blot.

a Multivariable predictors were adjusted for the covariates listed in the table.

b Increased risk per 1 log increase in antibody titer.

c Increased risk of bronchiectasis per unit increase in HTLV-1c proviral load.

d Eosinophils > 0.7 × 109/L for at least 12 months.

eStrongyloides serology result.

f Admission specifically for the treatment of a skin infection.

g Infective (infective dermatitis, 3; complicated strongyloidiasis, 2) and inflammatory (uveitis, 1; pericarditis, 1) conditions likely to be HTLV-1 associated.

hHaemophilus influenzae isolated from sputum prior to a formal diagnosis of bronchiectasis.

i Harmful alcohol consumption.

Table 3.

Univariable and Multivariable Predictors of Bronchiectasisa

Univariable Predictors
Multivariable Predictors
RR95% CIP ValueRR95% CIP Value
HTLV-1 Studies
 WB3.792.23–6.42.0001.841.19–2.84.006
 Ab titerb1.181.05–1.32.006
 PVLc1.211.08–1.36.001
Eosinophiliad1.961.21–3.19.006
Strongyloidese
 Positive2.231.31–3.79.0031.691.13–2.53.011
 Equivocal2.561.53–4.28.0001.831.18–2.82.006
Skin Infections
 Childhoodf3.772.36–6.03.0001.621.07–2.44.022
 Adulthoodf1.861.24–2.78.003
 Scabies1.741.04–2.92.036
IDH2.091.63–2.68.000
HTLV-1-associated conditionsg2.241.71–2.94.000
Haemophilus influenzaeh1.091.03–1.14.001
Alcoholi0.630.40–0.97.037
Univariable Predictors
Multivariable Predictors
RR95% CIP ValueRR95% CIP Value
HTLV-1 Studies
 WB3.792.23–6.42.0001.841.19–2.84.006
 Ab titerb1.181.05–1.32.006
 PVLc1.211.08–1.36.001
Eosinophiliad1.961.21–3.19.006
Strongyloidese
 Positive2.231.31–3.79.0031.691.13–2.53.011
 Equivocal2.561.53–4.28.0001.831.18–2.82.006
Skin Infections
 Childhoodf3.772.36–6.03.0001.621.07–2.44.022
 Adulthoodf1.861.24–2.78.003
 Scabies1.741.04–2.92.036
IDH2.091.63–2.68.000
HTLV-1-associated conditionsg2.241.71–2.94.000
Haemophilus influenzaeh1.091.03–1.14.001
Alcoholi0.630.40–0.97.037

Abbreviations: Ab, HTLV-1 antibody titer; CI, confidence interval; HTLV-1, human T-lymphotropic virus type 1; IDH, HTLV-1-associated infective dermatitis; RR, relative risk; PVL, proviral load; WB, Western blot.

a Multivariable predictors were adjusted for the covariates listed in the table.

b Increased risk per 1 log increase in antibody titer.

c Increased risk of bronchiectasis per unit increase in HTLV-1c proviral load.

d Eosinophils > 0.7 × 109/L for at least 12 months.

eStrongyloides serology result.

f Admission specifically for the treatment of a skin infection.

g Infective (infective dermatitis, 3; complicated strongyloidiasis, 2) and inflammatory (uveitis, 1; pericarditis, 1) conditions likely to be HTLV-1 associated.

hHaemophilus influenzae isolated from sputum prior to a formal diagnosis of bronchiectasis.

i Harmful alcohol consumption.

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