Table 1.

Review of Cases of Rat-Bite Fever in Pet Shop Employees

Ref.Age/SexRat ExposureUnderlying ConditionVisiting Time From OnsetClinical FeaturesComplicationsBlood CulturesIdentification MethodAntimicrobial TreatmentTreatment DurationOutcome
Present case39/MBite, scratchNone5 daysFever, headache, arthralgia, axillary lymphadenopathyArthritisPositiveMALDI-TOFCeftriaxone + oral doxycycline; oral amoxicillin28 daysCured
[5]24/MScratched by cageNone9–10 daysFever, malaise, bodyache, arthralgia, dyspnea, vomitingEndocarditis, myocardial abscessPositiveNRAmpicillin/ sulbactam; ceftriaxone; various45 daysDied
[8]52/FBiteNone2 daysHeadache, abdominal pain, diarrhea, lethargy, axillary lymphadenopathy, myalgia, arthralgiaHypotension, thrombocytopenia, multiple organ failurePositive16S rRNACiprofloxacin + metronidazole + vancomycin12 hoursDied
[15]60/FBiteBreast cancer21 daysFever, polyarthralgiaArthritisNegative16S rRNAPenicillin; oral rifampicin + clindamycin28 daysCured
Ref.Age/SexRat ExposureUnderlying ConditionVisiting Time From OnsetClinical FeaturesComplicationsBlood CulturesIdentification MethodAntimicrobial TreatmentTreatment DurationOutcome
Present case39/MBite, scratchNone5 daysFever, headache, arthralgia, axillary lymphadenopathyArthritisPositiveMALDI-TOFCeftriaxone + oral doxycycline; oral amoxicillin28 daysCured
[5]24/MScratched by cageNone9–10 daysFever, malaise, bodyache, arthralgia, dyspnea, vomitingEndocarditis, myocardial abscessPositiveNRAmpicillin/ sulbactam; ceftriaxone; various45 daysDied
[8]52/FBiteNone2 daysHeadache, abdominal pain, diarrhea, lethargy, axillary lymphadenopathy, myalgia, arthralgiaHypotension, thrombocytopenia, multiple organ failurePositive16S rRNACiprofloxacin + metronidazole + vancomycin12 hoursDied
[15]60/FBiteBreast cancer21 daysFever, polyarthralgiaArthritisNegative16S rRNAPenicillin; oral rifampicin + clindamycin28 daysCured

Abbreviations: F, female; M, male; MALDI-TOF, matrix-assisted laser desorption ionization time-of-flight; NR, not reported; rRNA, ribosomal ribonucleic acid.

Table 1.

Review of Cases of Rat-Bite Fever in Pet Shop Employees

Ref.Age/SexRat ExposureUnderlying ConditionVisiting Time From OnsetClinical FeaturesComplicationsBlood CulturesIdentification MethodAntimicrobial TreatmentTreatment DurationOutcome
Present case39/MBite, scratchNone5 daysFever, headache, arthralgia, axillary lymphadenopathyArthritisPositiveMALDI-TOFCeftriaxone + oral doxycycline; oral amoxicillin28 daysCured
[5]24/MScratched by cageNone9–10 daysFever, malaise, bodyache, arthralgia, dyspnea, vomitingEndocarditis, myocardial abscessPositiveNRAmpicillin/ sulbactam; ceftriaxone; various45 daysDied
[8]52/FBiteNone2 daysHeadache, abdominal pain, diarrhea, lethargy, axillary lymphadenopathy, myalgia, arthralgiaHypotension, thrombocytopenia, multiple organ failurePositive16S rRNACiprofloxacin + metronidazole + vancomycin12 hoursDied
[15]60/FBiteBreast cancer21 daysFever, polyarthralgiaArthritisNegative16S rRNAPenicillin; oral rifampicin + clindamycin28 daysCured
Ref.Age/SexRat ExposureUnderlying ConditionVisiting Time From OnsetClinical FeaturesComplicationsBlood CulturesIdentification MethodAntimicrobial TreatmentTreatment DurationOutcome
Present case39/MBite, scratchNone5 daysFever, headache, arthralgia, axillary lymphadenopathyArthritisPositiveMALDI-TOFCeftriaxone + oral doxycycline; oral amoxicillin28 daysCured
[5]24/MScratched by cageNone9–10 daysFever, malaise, bodyache, arthralgia, dyspnea, vomitingEndocarditis, myocardial abscessPositiveNRAmpicillin/ sulbactam; ceftriaxone; various45 daysDied
[8]52/FBiteNone2 daysHeadache, abdominal pain, diarrhea, lethargy, axillary lymphadenopathy, myalgia, arthralgiaHypotension, thrombocytopenia, multiple organ failurePositive16S rRNACiprofloxacin + metronidazole + vancomycin12 hoursDied
[15]60/FBiteBreast cancer21 daysFever, polyarthralgiaArthritisNegative16S rRNAPenicillin; oral rifampicin + clindamycin28 daysCured

Abbreviations: F, female; M, male; MALDI-TOF, matrix-assisted laser desorption ionization time-of-flight; NR, not reported; rRNA, ribosomal ribonucleic acid.

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