Table 2

Topological parameters for the constructed drug–drug interaction network

Topological parameterDescriptionValue
No. of nodesNumber of drugs in the network175
No. of edgesNumber of drug pairs in the network1888
Connected componentsA set of vertices in a graph that are linked to each other by paths1
DiameterLength of the longest shortest path between each pair of nodes in the network6
DensityThe ratio of actual connections and potential connections in the network0.124
CentralizationNetwork centralization0.345
Clustering coefficientsA coefficient used to describe the degree of clustering between vertices in a graph0.498
Shortest pathsSum of length of all shortest paths in the network30450 (100%)
Characteristic path lengthNetwork characteristic path length2.229
Avg. number of neighborsAverage degree of drugs in the network21.577
Topological parameterDescriptionValue
No. of nodesNumber of drugs in the network175
No. of edgesNumber of drug pairs in the network1888
Connected componentsA set of vertices in a graph that are linked to each other by paths1
DiameterLength of the longest shortest path between each pair of nodes in the network6
DensityThe ratio of actual connections and potential connections in the network0.124
CentralizationNetwork centralization0.345
Clustering coefficientsA coefficient used to describe the degree of clustering between vertices in a graph0.498
Shortest pathsSum of length of all shortest paths in the network30450 (100%)
Characteristic path lengthNetwork characteristic path length2.229
Avg. number of neighborsAverage degree of drugs in the network21.577
Table 2

Topological parameters for the constructed drug–drug interaction network

Topological parameterDescriptionValue
No. of nodesNumber of drugs in the network175
No. of edgesNumber of drug pairs in the network1888
Connected componentsA set of vertices in a graph that are linked to each other by paths1
DiameterLength of the longest shortest path between each pair of nodes in the network6
DensityThe ratio of actual connections and potential connections in the network0.124
CentralizationNetwork centralization0.345
Clustering coefficientsA coefficient used to describe the degree of clustering between vertices in a graph0.498
Shortest pathsSum of length of all shortest paths in the network30450 (100%)
Characteristic path lengthNetwork characteristic path length2.229
Avg. number of neighborsAverage degree of drugs in the network21.577
Topological parameterDescriptionValue
No. of nodesNumber of drugs in the network175
No. of edgesNumber of drug pairs in the network1888
Connected componentsA set of vertices in a graph that are linked to each other by paths1
DiameterLength of the longest shortest path between each pair of nodes in the network6
DensityThe ratio of actual connections and potential connections in the network0.124
CentralizationNetwork centralization0.345
Clustering coefficientsA coefficient used to describe the degree of clustering between vertices in a graph0.498
Shortest pathsSum of length of all shortest paths in the network30450 (100%)
Characteristic path lengthNetwork characteristic path length2.229
Avg. number of neighborsAverage degree of drugs in the network21.577
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