Table 1. Open in new tab Baseline...

	Total	Chlamydia	Gonorrhea	Syphilis	Any STI
	6762		250	3.7		212	3.1		123	1.8		451	6.7
Age at enrollment, y
0–17	149	2.2	10	6.7	4.0	7	4.7	3.3	1	0.7	0.8	11	7.4	2.4
18–34	1377	20.4	137	9.9	54.8	114	8.3	53.8	45	3.3	36.6	220	16.0	48.8
35–54	3637	53.8	95	2.6	38.0	80	2.2	37.7	69	1.9	56.1	196	5.4	43.5
55+	1599	23.6	8	0.5	3.2	11	0.7	5.2	8	0.5	6.5	24	1.5	5.3
Age at consent, median (IQR)	47.0 (36.5–54.5)	32.8 (25.6–42.3)	32.1 (26.0–42.9)	38.9 (31.6–47.4)	34.8 (26.9–44.3)
Gender at consent
Male	4823	71.3	210	4.4	84.0	187	3.9	88.2	116	2.4	94.3	392	8.1	86.9
Female	1821	26.9	29	1.6	11.6	15	0.8	7.1	3	0.2	2.4	39	2.1	8.6
Transgender female	113	1.7	11	9.7	4.4	10	8.8	4.7	4	3.5	3.3	20	17.7	4.4
Transgender male	5	0.1	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Race/ethnicity^b
Non-Hispanic black	5161	76.3	169	3.3	67.6	132	2.6	62.3	75	1.5	61.0	290	5.6	64.3
Non-Hispanic white	940	13.9	54	5.7	21.6	52	5.5	24.5	28	3.0	22.8	101	10.7	22.4
Hispanic	314	4.6	21	6.7	8.4	23	7.3	10.8	11	3.5	8.9	43	13.7	9.5
Other	137	2.0	3	2.2	1.2	4	2.9	1.9	1	0.7	0.8	6	4.4	1.3
Unknown	210	3.1	3	1.4	1.2	1	0.5	0.5	8	3.8	6.5	11	5.2	2.4
HIV risk behavior^c
MSM	2652	39.2	196	7.4	78.4	181	6.8	85.4	109	4.1	88.6	365	13.8	80.9
HRH	1989	29.4	23	1.2	9.2	11	0.6	5.2	4	0.2	3.3	35	1.8	7.8
IDU	452	6.7	1	0.2	0.4	1	0.2	0.5	0	0.0	0.0	2	0.4	0.4
Other	354	5.2	11	3.1	4.4	8	2.3	3.8	0	0.0	0.0	14	4.0	3.1
Unknown	1315	19.4	19	1.4	7.6	11	0.8	5.2	10	0.8	8.1	35	2.7	7.8
Nadir CD4 cell count, cells/mm^3d
<50	1056	15.6	17	1.6	6.8	17	1.6	8.0	9	0.9	7.3	37	3.5	8.2
50–199	1452	21.5	38	2.6	15.2	35	2.4	16.5	30	2.1	24.4	81	5.6	18.0
200–349	1703	25.2	74	4.3	29.6	72	4.2	34.0	34	2.0	27.6	137	8.0	30.4
350–499	1265	18.7	63	5.0	25.2	46	3.6	21.7	32	2.5	26.0	107	8.5	23.7
500+	1279	18.9	58	4.5	23.2	42	3.3	19.8	17	1.3	13.8	88	6.9	19.5
Housing at index date^e
Permanent/stable	4486	66.3	152	3.4	60.8	124	2.8	58.5	86	1.9	69.9	281	6.3	62.3
Temporary/unstable/homeless	530	7.8	29	5.5	11.6	31	5.8	14.6	17	3.2	13.8	59	11.1	13.1
Other	15	0.2	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Unknown	1731	25.6	69	4.0	27.6	57	3.3	26.9	20	1.2	16.3	111	6.4	24.6
Primary insurance at consent^f
Public	4313	63.8	137	3.2	54.8	119	2.8	56.1	56	1.3	45.5	239	5.5	53.0
Private	1819	26.9	72	4.0	28.8	60	3.3	28.3	54	3.0	43.9	143	7.9	31.7
Other	427	6.3	19	4.4	7.6	11	2.6	5.2	9	2.1	7.3	34	8.0	7.5
Unknown	203	3.0	22	10.8	8.8	22	10.8	10.4	4	2.0	3.3	35	17.2	7.8
Alcohol use at consent
Yes	906	13.4	49	5.4	19.6	42	4.6	19.8	23	2.5	18.7	89	9.8	19.7
No	4149	61.4	104	2.5	41.6	83	2.0	39.2	45	1.1	36.6	193	4.7	42.8
Unknown	1707	25.2	97	5.7	38.8	87	5.1	41.0	55	3.2	44.7	169	9.9	37.5
Substance abuse at consent
Yes	822	12.2	54	6.6	21.6	49	6.0	23.1	24	2.9	19.5	87	10.6	19.3
No	3787	56.0	97	2.6	38.8	73	1.9	34.4	52	1.4	42.3	178	4.7	39.5
Unknown	2153	31.8	99	4.6	39.6	90	4.2	42.5	47	2.2	38.2	186	8.6	41.2
Diagnoses of mental health conditions at consent^g	341	5.0	3	0.9	1.2	2	0.6	0.9	0	0.0	0.0	4	1.2	0.9
Ever HBV infection prior to consent	379	5.6	13	3.4	5.2	8	2.1	3.8	10	2.6	8.1	27	7.1	6.0
Ever HCV infection prior to consent	780	11.5	14	1.8	5.6	12	1.5	5.7	7	0.9	5.7	28	3.6	6.2

	Total	Chlamydia	Gonorrhea	Syphilis	Any STI
	6762		250	3.7		212	3.1		123	1.8		451	6.7
Age at enrollment, y
0–17	149	2.2	10	6.7	4.0	7	4.7	3.3	1	0.7	0.8	11	7.4	2.4
18–34	1377	20.4	137	9.9	54.8	114	8.3	53.8	45	3.3	36.6	220	16.0	48.8
35–54	3637	53.8	95	2.6	38.0	80	2.2	37.7	69	1.9	56.1	196	5.4	43.5
55+	1599	23.6	8	0.5	3.2	11	0.7	5.2	8	0.5	6.5	24	1.5	5.3
Age at consent, median (IQR)	47.0 (36.5–54.5)	32.8 (25.6–42.3)	32.1 (26.0–42.9)	38.9 (31.6–47.4)	34.8 (26.9–44.3)
Gender at consent
Male	4823	71.3	210	4.4	84.0	187	3.9	88.2	116	2.4	94.3	392	8.1	86.9
Female	1821	26.9	29	1.6	11.6	15	0.8	7.1	3	0.2	2.4	39	2.1	8.6
Transgender female	113	1.7	11	9.7	4.4	10	8.8	4.7	4	3.5	3.3	20	17.7	4.4
Transgender male	5	0.1	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Race/ethnicity^b
Non-Hispanic black	5161	76.3	169	3.3	67.6	132	2.6	62.3	75	1.5	61.0	290	5.6	64.3
Non-Hispanic white	940	13.9	54	5.7	21.6	52	5.5	24.5	28	3.0	22.8	101	10.7	22.4
Hispanic	314	4.6	21	6.7	8.4	23	7.3	10.8	11	3.5	8.9	43	13.7	9.5
Other	137	2.0	3	2.2	1.2	4	2.9	1.9	1	0.7	0.8	6	4.4	1.3
Unknown	210	3.1	3	1.4	1.2	1	0.5	0.5	8	3.8	6.5	11	5.2	2.4
HIV risk behavior^c
MSM	2652	39.2	196	7.4	78.4	181	6.8	85.4	109	4.1	88.6	365	13.8	80.9
HRH	1989	29.4	23	1.2	9.2	11	0.6	5.2	4	0.2	3.3	35	1.8	7.8
IDU	452	6.7	1	0.2	0.4	1	0.2	0.5	0	0.0	0.0	2	0.4	0.4
Other	354	5.2	11	3.1	4.4	8	2.3	3.8	0	0.0	0.0	14	4.0	3.1
Unknown	1315	19.4	19	1.4	7.6	11	0.8	5.2	10	0.8	8.1	35	2.7	7.8
Nadir CD4 cell count, cells/mm^3d
<50	1056	15.6	17	1.6	6.8	17	1.6	8.0	9	0.9	7.3	37	3.5	8.2
50–199	1452	21.5	38	2.6	15.2	35	2.4	16.5	30	2.1	24.4	81	5.6	18.0
200–349	1703	25.2	74	4.3	29.6	72	4.2	34.0	34	2.0	27.6	137	8.0	30.4
350–499	1265	18.7	63	5.0	25.2	46	3.6	21.7	32	2.5	26.0	107	8.5	23.7
500+	1279	18.9	58	4.5	23.2	42	3.3	19.8	17	1.3	13.8	88	6.9	19.5
Housing at index date^e
Permanent/stable	4486	66.3	152	3.4	60.8	124	2.8	58.5	86	1.9	69.9	281	6.3	62.3
Temporary/unstable/homeless	530	7.8	29	5.5	11.6	31	5.8	14.6	17	3.2	13.8	59	11.1	13.1
Other	15	0.2	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Unknown	1731	25.6	69	4.0	27.6	57	3.3	26.9	20	1.2	16.3	111	6.4	24.6
Primary insurance at consent^f
Public	4313	63.8	137	3.2	54.8	119	2.8	56.1	56	1.3	45.5	239	5.5	53.0
Private	1819	26.9	72	4.0	28.8	60	3.3	28.3	54	3.0	43.9	143	7.9	31.7
Other	427	6.3	19	4.4	7.6	11	2.6	5.2	9	2.1	7.3	34	8.0	7.5
Unknown	203	3.0	22	10.8	8.8	22	10.8	10.4	4	2.0	3.3	35	17.2	7.8
Alcohol use at consent
Yes	906	13.4	49	5.4	19.6	42	4.6	19.8	23	2.5	18.7	89	9.8	19.7
No	4149	61.4	104	2.5	41.6	83	2.0	39.2	45	1.1	36.6	193	4.7	42.8
Unknown	1707	25.2	97	5.7	38.8	87	5.1	41.0	55	3.2	44.7	169	9.9	37.5
Substance abuse at consent
Yes	822	12.2	54	6.6	21.6	49	6.0	23.1	24	2.9	19.5	87	10.6	19.3
No	3787	56.0	97	2.6	38.8	73	1.9	34.4	52	1.4	42.3	178	4.7	39.5
Unknown	2153	31.8	99	4.6	39.6	90	4.2	42.5	47	2.2	38.2	186	8.6	41.2
Diagnoses of mental health conditions at consent^g	341	5.0	3	0.9	1.2	2	0.6	0.9	0	0.0	0.0	4	1.2	0.9
Ever HBV infection prior to consent	379	5.6	13	3.4	5.2	8	2.1	3.8	10	2.6	8.1	27	7.1	6.0
Ever HCV infection prior to consent	780	11.5	14	1.8	5.6	12	1.5	5.7	7	0.9	5.7	28	3.6	6.2

Table 1.

Baseline Characteristics^a of the DC Cohort Participants by Incident STIs (n = 6762)

	Total		Chlamydia			Gonorrhea			Syphilis			Any STI
	No.	Column %	No.	Row %	Column %	No.	Row %	Column %	No.	Row %	Column %	No.	Row %	Column %
	6762		250	3.7		212	3.1		123	1.8		451	6.7
Age at enrollment, y
0–17	149	2.2	10	6.7	4.0	7	4.7	3.3	1	0.7	0.8	11	7.4	2.4
18–34	1377	20.4	137	9.9	54.8	114	8.3	53.8	45	3.3	36.6	220	16.0	48.8
35–54	3637	53.8	95	2.6	38.0	80	2.2	37.7	69	1.9	56.1	196	5.4	43.5
55+	1599	23.6	8	0.5	3.2	11	0.7	5.2	8	0.5	6.5	24	1.5	5.3
Age at consent, median (IQR)	47.0 (36.5–54.5)		32.8 (25.6–42.3)			32.1 (26.0–42.9)			38.9 (31.6–47.4)			34.8 (26.9–44.3)
Gender at consent
Male	4823	71.3	210	4.4	84.0	187	3.9	88.2	116	2.4	94.3	392	8.1	86.9
Female	1821	26.9	29	1.6	11.6	15	0.8	7.1	3	0.2	2.4	39	2.1	8.6
Transgender female	113	1.7	11	9.7	4.4	10	8.8	4.7	4	3.5	3.3	20	17.7	4.4
Transgender male	5	0.1	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Race/ethnicity^b
Non-Hispanic black	5161	76.3	169	3.3	67.6	132	2.6	62.3	75	1.5	61.0	290	5.6	64.3
Non-Hispanic white	940	13.9	54	5.7	21.6	52	5.5	24.5	28	3.0	22.8	101	10.7	22.4
Hispanic	314	4.6	21	6.7	8.4	23	7.3	10.8	11	3.5	8.9	43	13.7	9.5
Other	137	2.0	3	2.2	1.2	4	2.9	1.9	1	0.7	0.8	6	4.4	1.3
Unknown	210	3.1	3	1.4	1.2	1	0.5	0.5	8	3.8	6.5	11	5.2	2.4
HIV risk behavior^c
MSM	2652	39.2	196	7.4	78.4	181	6.8	85.4	109	4.1	88.6	365	13.8	80.9
HRH	1989	29.4	23	1.2	9.2	11	0.6	5.2	4	0.2	3.3	35	1.8	7.8
IDU	452	6.7	1	0.2	0.4	1	0.2	0.5	0	0.0	0.0	2	0.4	0.4
Other	354	5.2	11	3.1	4.4	8	2.3	3.8	0	0.0	0.0	14	4.0	3.1
Unknown	1315	19.4	19	1.4	7.6	11	0.8	5.2	10	0.8	8.1	35	2.7	7.8
Nadir CD4 cell count, cells/mm^3d
<50	1056	15.6	17	1.6	6.8	17	1.6	8.0	9	0.9	7.3	37	3.5	8.2
50–199	1452	21.5	38	2.6	15.2	35	2.4	16.5	30	2.1	24.4	81	5.6	18.0
200–349	1703	25.2	74	4.3	29.6	72	4.2	34.0	34	2.0	27.6	137	8.0	30.4
350–499	1265	18.7	63	5.0	25.2	46	3.6	21.7	32	2.5	26.0	107	8.5	23.7
500+	1279	18.9	58	4.5	23.2	42	3.3	19.8	17	1.3	13.8	88	6.9	19.5
Housing at index date^e
Permanent/stable	4486	66.3	152	3.4	60.8	124	2.8	58.5	86	1.9	69.9	281	6.3	62.3
Temporary/unstable/homeless	530	7.8	29	5.5	11.6	31	5.8	14.6	17	3.2	13.8	59	11.1	13.1
Other	15	0.2	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Unknown	1731	25.6	69	4.0	27.6	57	3.3	26.9	20	1.2	16.3	111	6.4	24.6
Primary insurance at consent^f
Public	4313	63.8	137	3.2	54.8	119	2.8	56.1	56	1.3	45.5	239	5.5	53.0
Private	1819	26.9	72	4.0	28.8	60	3.3	28.3	54	3.0	43.9	143	7.9	31.7
Other	427	6.3	19	4.4	7.6	11	2.6	5.2	9	2.1	7.3	34	8.0	7.5
Unknown	203	3.0	22	10.8	8.8	22	10.8	10.4	4	2.0	3.3	35	17.2	7.8
Alcohol use at consent
Yes	906	13.4	49	5.4	19.6	42	4.6	19.8	23	2.5	18.7	89	9.8	19.7
No	4149	61.4	104	2.5	41.6	83	2.0	39.2	45	1.1	36.6	193	4.7	42.8
Unknown	1707	25.2	97	5.7	38.8	87	5.1	41.0	55	3.2	44.7	169	9.9	37.5
Substance abuse at consent
Yes	822	12.2	54	6.6	21.6	49	6.0	23.1	24	2.9	19.5	87	10.6	19.3
No	3787	56.0	97	2.6	38.8	73	1.9	34.4	52	1.4	42.3	178	4.7	39.5
Unknown	2153	31.8	99	4.6	39.6	90	4.2	42.5	47	2.2	38.2	186	8.6	41.2
Diagnoses of mental health conditions at consent^g	341	5.0	3	0.9	1.2	2	0.6	0.9	0	0.0	0.0	4	1.2	0.9
Ever HBV infection prior to consent	379	5.6	13	3.4	5.2	8	2.1	3.8	10	2.6	8.1	27	7.1	6.0
Ever HCV infection prior to consent	780	11.5	14	1.8	5.6	12	1.5	5.7	7	0.9	5.7	28	3.6	6.2

	Total		Chlamydia			Gonorrhea			Syphilis			Any STI
	No.	Column %	No.	Row %	Column %	No.	Row %	Column %	No.	Row %	Column %	No.	Row %	Column %
	6762		250	3.7		212	3.1		123	1.8		451	6.7
Age at enrollment, y
0–17	149	2.2	10	6.7	4.0	7	4.7	3.3	1	0.7	0.8	11	7.4	2.4
18–34	1377	20.4	137	9.9	54.8	114	8.3	53.8	45	3.3	36.6	220	16.0	48.8
35–54	3637	53.8	95	2.6	38.0	80	2.2	37.7	69	1.9	56.1	196	5.4	43.5
55+	1599	23.6	8	0.5	3.2	11	0.7	5.2	8	0.5	6.5	24	1.5	5.3
Age at consent, median (IQR)	47.0 (36.5–54.5)		32.8 (25.6–42.3)			32.1 (26.0–42.9)			38.9 (31.6–47.4)			34.8 (26.9–44.3)
Gender at consent
Male	4823	71.3	210	4.4	84.0	187	3.9	88.2	116	2.4	94.3	392	8.1	86.9
Female	1821	26.9	29	1.6	11.6	15	0.8	7.1	3	0.2	2.4	39	2.1	8.6
Transgender female	113	1.7	11	9.7	4.4	10	8.8	4.7	4	3.5	3.3	20	17.7	4.4
Transgender male	5	0.1	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Race/ethnicity^b
Non-Hispanic black	5161	76.3	169	3.3	67.6	132	2.6	62.3	75	1.5	61.0	290	5.6	64.3
Non-Hispanic white	940	13.9	54	5.7	21.6	52	5.5	24.5	28	3.0	22.8	101	10.7	22.4
Hispanic	314	4.6	21	6.7	8.4	23	7.3	10.8	11	3.5	8.9	43	13.7	9.5
Other	137	2.0	3	2.2	1.2	4	2.9	1.9	1	0.7	0.8	6	4.4	1.3
Unknown	210	3.1	3	1.4	1.2	1	0.5	0.5	8	3.8	6.5	11	5.2	2.4
HIV risk behavior^c
MSM	2652	39.2	196	7.4	78.4	181	6.8	85.4	109	4.1	88.6	365	13.8	80.9
HRH	1989	29.4	23	1.2	9.2	11	0.6	5.2	4	0.2	3.3	35	1.8	7.8
IDU	452	6.7	1	0.2	0.4	1	0.2	0.5	0	0.0	0.0	2	0.4	0.4
Other	354	5.2	11	3.1	4.4	8	2.3	3.8	0	0.0	0.0	14	4.0	3.1
Unknown	1315	19.4	19	1.4	7.6	11	0.8	5.2	10	0.8	8.1	35	2.7	7.8
Nadir CD4 cell count, cells/mm^3d
<50	1056	15.6	17	1.6	6.8	17	1.6	8.0	9	0.9	7.3	37	3.5	8.2
50–199	1452	21.5	38	2.6	15.2	35	2.4	16.5	30	2.1	24.4	81	5.6	18.0
200–349	1703	25.2	74	4.3	29.6	72	4.2	34.0	34	2.0	27.6	137	8.0	30.4
350–499	1265	18.7	63	5.0	25.2	46	3.6	21.7	32	2.5	26.0	107	8.5	23.7
500+	1279	18.9	58	4.5	23.2	42	3.3	19.8	17	1.3	13.8	88	6.9	19.5
Housing at index date^e
Permanent/stable	4486	66.3	152	3.4	60.8	124	2.8	58.5	86	1.9	69.9	281	6.3	62.3
Temporary/unstable/homeless	530	7.8	29	5.5	11.6	31	5.8	14.6	17	3.2	13.8	59	11.1	13.1
Other	15	0.2	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0	0	0.0	0.0
Unknown	1731	25.6	69	4.0	27.6	57	3.3	26.9	20	1.2	16.3	111	6.4	24.6
Primary insurance at consent^f
Public	4313	63.8	137	3.2	54.8	119	2.8	56.1	56	1.3	45.5	239	5.5	53.0
Private	1819	26.9	72	4.0	28.8	60	3.3	28.3	54	3.0	43.9	143	7.9	31.7
Other	427	6.3	19	4.4	7.6	11	2.6	5.2	9	2.1	7.3	34	8.0	7.5
Unknown	203	3.0	22	10.8	8.8	22	10.8	10.4	4	2.0	3.3	35	17.2	7.8
Alcohol use at consent
Yes	906	13.4	49	5.4	19.6	42	4.6	19.8	23	2.5	18.7	89	9.8	19.7
No	4149	61.4	104	2.5	41.6	83	2.0	39.2	45	1.1	36.6	193	4.7	42.8
Unknown	1707	25.2	97	5.7	38.8	87	5.1	41.0	55	3.2	44.7	169	9.9	37.5
Substance abuse at consent
Yes	822	12.2	54	6.6	21.6	49	6.0	23.1	24	2.9	19.5	87	10.6	19.3
No	3787	56.0	97	2.6	38.8	73	1.9	34.4	52	1.4	42.3	178	4.7	39.5
Unknown	2153	31.8	99	4.6	39.6	90	4.2	42.5	47	2.2	38.2	186	8.6	41.2
Diagnoses of mental health conditions at consent^g	341	5.0	3	0.9	1.2	2	0.6	0.9	0	0.0	0.0	4	1.2	0.9
Ever HBV infection prior to consent	379	5.6	13	3.4	5.2	8	2.1	3.8	10	2.6	8.1	27	7.1	6.0
Ever HCV infection prior to consent	780	11.5	14	1.8	5.6	12	1.5	5.7	7	0.9	5.7	28	3.6	6.2

Abbreviations: HBV, hepatitis B virus; HCV, hepatitis C virus; HRH, heterosexual; IDU, injection drug user; IQR, interquartile range; MSM, men who have sex with men; STI, sexually transmitted infection.

^aAll characteristics are at the time of consent into the DC Cohort.

^bOther race/ethnicity includes persons of Asian/Pacific Island descent and those with more than 1 reported race.

^cHIV risk behaviors: HRH, IDU, MSM. MSM who are also IDUs are grouped with MSM. Other HIV transmission risk behavior includes persons who were perinatally infected or infected through blood transfusions, coagulation disorders, or occupational exposures.

^dNadir CD4 is the lowest CD4 record available dated prior to enrollment into the DC Cohort. Seven participants had an unknown nadir CD4 cell count.

^eTemporary/unstable housing was defined as a housing unit in which persons who are without housing or a fixed address receive temporary housing or shelter.

^fPublic insurance includes Medicare, Medicaid, and other public insurance coverage plans; “Other” insurance includes self-pay, recently terminated plans, clinical trial.

^gMental health conditions diagnosed previously or at the time of consent include major depressive disorder, anxiety disorder, bipolar disorder, psychoses, other.

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