Relative risk of chronic thyroid diseases in individuals with nonmedullary thyroid cancer–affected first-degree relatives vs the general population of Taiwan
. | . | With affected relatives . | General population . | . | ||
---|---|---|---|---|---|---|
. | Sex . | No. . | Prevalence, ‰ . | No. . | Prevalence, ‰ . | Adjusted RRa (95% CI) . |
Thyroid nodule | Male | 625 | 16.60 | 95 389 | 8.08 | 2.62 (2.42-2.83)b |
Female | 2487 | 68.89 | 456 838 | 38.44 | 2.19 (2.11-2.28)b | |
All | 3112 | 42.19 | 552 227 | 23.30 | 2.26 (2.18-2.35)b | |
Hashimoto thyroiditis | Male | 38 | 1.01 | 6723 | 0.57 | 2.11 (1.53-2.91)b |
Female | 298 | 8.25 | 52 222 | 4.39 | 2.11 (1.88-2.38)b | |
All | 336 | 4.56 | 58 945 | 2.49 | 2.11 (1.89-2.36)b | |
Graves disease | Male | 352 | 9.35 | 84 854 | 7.18 | 1.56 (1.40-1.74)b |
Female | 1145 | 31.72 | 300 869 | 25.32 | 1.48 (1.39-1.56)b | |
All | 1497 | 20.30 | 385 723 | 16.28 | 1.49 (1.42-1.57)b |
. | . | With affected relatives . | General population . | . | ||
---|---|---|---|---|---|---|
. | Sex . | No. . | Prevalence, ‰ . | No. . | Prevalence, ‰ . | Adjusted RRa (95% CI) . |
Thyroid nodule | Male | 625 | 16.60 | 95 389 | 8.08 | 2.62 (2.42-2.83)b |
Female | 2487 | 68.89 | 456 838 | 38.44 | 2.19 (2.11-2.28)b | |
All | 3112 | 42.19 | 552 227 | 23.30 | 2.26 (2.18-2.35)b | |
Hashimoto thyroiditis | Male | 38 | 1.01 | 6723 | 0.57 | 2.11 (1.53-2.91)b |
Female | 298 | 8.25 | 52 222 | 4.39 | 2.11 (1.88-2.38)b | |
All | 336 | 4.56 | 58 945 | 2.49 | 2.11 (1.89-2.36)b | |
Graves disease | Male | 352 | 9.35 | 84 854 | 7.18 | 1.56 (1.40-1.74)b |
Female | 1145 | 31.72 | 300 869 | 25.32 | 1.48 (1.39-1.56)b | |
All | 1497 | 20.30 | 385 723 | 16.28 | 1.49 (1.42-1.57)b |
Abbreviation: RR, relative risk.
aAdjusted for age, sex, place of residence, quintiles of income level, occupation, and family size.
bP less than .05.
Relative risk of chronic thyroid diseases in individuals with nonmedullary thyroid cancer–affected first-degree relatives vs the general population of Taiwan
. | . | With affected relatives . | General population . | . | ||
---|---|---|---|---|---|---|
. | Sex . | No. . | Prevalence, ‰ . | No. . | Prevalence, ‰ . | Adjusted RRa (95% CI) . |
Thyroid nodule | Male | 625 | 16.60 | 95 389 | 8.08 | 2.62 (2.42-2.83)b |
Female | 2487 | 68.89 | 456 838 | 38.44 | 2.19 (2.11-2.28)b | |
All | 3112 | 42.19 | 552 227 | 23.30 | 2.26 (2.18-2.35)b | |
Hashimoto thyroiditis | Male | 38 | 1.01 | 6723 | 0.57 | 2.11 (1.53-2.91)b |
Female | 298 | 8.25 | 52 222 | 4.39 | 2.11 (1.88-2.38)b | |
All | 336 | 4.56 | 58 945 | 2.49 | 2.11 (1.89-2.36)b | |
Graves disease | Male | 352 | 9.35 | 84 854 | 7.18 | 1.56 (1.40-1.74)b |
Female | 1145 | 31.72 | 300 869 | 25.32 | 1.48 (1.39-1.56)b | |
All | 1497 | 20.30 | 385 723 | 16.28 | 1.49 (1.42-1.57)b |
. | . | With affected relatives . | General population . | . | ||
---|---|---|---|---|---|---|
. | Sex . | No. . | Prevalence, ‰ . | No. . | Prevalence, ‰ . | Adjusted RRa (95% CI) . |
Thyroid nodule | Male | 625 | 16.60 | 95 389 | 8.08 | 2.62 (2.42-2.83)b |
Female | 2487 | 68.89 | 456 838 | 38.44 | 2.19 (2.11-2.28)b | |
All | 3112 | 42.19 | 552 227 | 23.30 | 2.26 (2.18-2.35)b | |
Hashimoto thyroiditis | Male | 38 | 1.01 | 6723 | 0.57 | 2.11 (1.53-2.91)b |
Female | 298 | 8.25 | 52 222 | 4.39 | 2.11 (1.88-2.38)b | |
All | 336 | 4.56 | 58 945 | 2.49 | 2.11 (1.89-2.36)b | |
Graves disease | Male | 352 | 9.35 | 84 854 | 7.18 | 1.56 (1.40-1.74)b |
Female | 1145 | 31.72 | 300 869 | 25.32 | 1.48 (1.39-1.56)b | |
All | 1497 | 20.30 | 385 723 | 16.28 | 1.49 (1.42-1.57)b |
Abbreviation: RR, relative risk.
aAdjusted for age, sex, place of residence, quintiles of income level, occupation, and family size.
bP less than .05.
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