Table 3. Open in new tab Relative risk...

Type of affected relatives

Sex of affected relatives

Sex of individual

No. of NMTC

Prevalence, ‰

Adjusted relative risks^a (95% CIs)

Any

Male

4.33

7.61 (4.84-11.97)^b

Female

11.07

5.36 (4.34-6.61)^b

All

121

7.63

5.84 (4.78-7.13)^b

Female

Male

2.90

5.71 (4.62-7.06)^b

Female

270

9.50

4.99 (4.23-5.89)^b

All

356

6.13

5.14 (4.49-5.89)^b

All

Male

119

3.16

6.07 (4.97-7.40)^b

Female

354

9.81

5.06 (4.42-5.79)^b

All

473

6.41

5.27 (4.65-5.97)^b

Parent

Father

Male

2.51

6.88 (4.09-11.56)^b

Female

5.37

4.33 (2.91-6.43)^b

All

3.84

4.96 (3.62-6.80)^b

Mother

Male

2.26

6.17 (4.68-8.14)^b

Female

115

5.92

4.74 (3.94-5.70)^b

All

164

3.99

5.08 (4.36-5.92)^b

All

Male

2.32

6.33 (4.96-8.07)^b

Female

141

5.82

4.67 (3.95-5.51)^b

All

204

3.97

5.07 (4.41-5.81)^b

Offspring

Son

Male

8.23

6.56 (3.66-11.78)^b

Female

24.23

6.04 (4.53-8.05)^b

All

17.54

6.11 (4.72-7.89)^b

Daughter

Male

5.70

4.63 (3.06-7.02)^b

Female

109

20.81

5.01 (4.16-6.02)^b

All

131

14.41

4.93 (4.16-5.83)^b

All

Male

6.36

5.14 (3.67-7.21)^b

Female

154

21.74

5.28 (4.53-6.17)^b

All

187

15.24

5.24 (4.55-6.03)^b

Sibling

Brother

Male

8.55

11.28 (4.74-26.87)^b

Female

13.93

5.75 (3.48-9.47)^b

All

11.13

7.17 (4.42-11.63)^b

Sister

Male

3.58

6.19 (3.63-10.59)^b

Female

13.25

6.45 (4.39-9.48)^b

All

8.16

6.37 (4.62-8.77)^b

All

Male

4.30

6.96 (4.28-11.32)^b

Female

13.41

6.28 (4.57-8.62)^b

All

8.63

6.43 (4.80-8.62)^b

Twins

Brother

Male

Female

All

Sister

Male

Female

62.50

25.95 (5.92-113.81)^b

All

45.98

23.03 (5.28-100.45)^b

All

Male

Female

58.82

23.45 (5.49-100.12)^b

All

38.10

20.12 (4.86-83.29)^b

Spouse

All

3.77

2.07 (1.53-2.81)^b

Table 3.

Open in new tab

Relative risk of nonmedullary thyroid cancer (NMTC) in individuals with NMTC-affected first-degree relatives vs the general population of Taiwan in 2016

Type of affected relatives	Sex of affected relatives	Sex of individual	No. of NMTC	Prevalence, ‰	Adjusted relative risks^a (95% CIs)
Any	Male	Male	35	4.33	7.61 (4.84-11.97)^b
		Female	86	11.07	5.36 (4.34-6.61)^b
		All	121	7.63	5.84 (4.78-7.13)^b
	Female	Male	86	2.90	5.71 (4.62-7.06)^b
		Female	270	9.50	4.99 (4.23-5.89)^b
		All	356	6.13	5.14 (4.49-5.89)^b
	All	Male	119	3.16	6.07 (4.97-7.40)^b
		Female	354	9.81	5.06 (4.42-5.79)^b
		All	473	6.41	5.27 (4.65-5.97)^b
Parent	Father	Male	14	2.51	6.88 (4.09-11.56)^b
		Female	26	5.37	4.33 (2.91-6.43)^b
		All	40	3.84	4.96 (3.62-6.80)^b
	Mother	Male	49	2.26	6.17 (4.68-8.14)^b
		Female	115	5.92	4.74 (3.94-5.70)^b
		All	164	3.99	5.08 (4.36-5.92)^b
	All	Male	63	2.32	6.33 (4.96-8.07)^b
		Female	141	5.82	4.67 (3.95-5.51)^b
		All	204	3.97	5.07 (4.41-5.81)^b
Offspring	Son	Male	11	8.23	6.56 (3.66-11.78)^b
		Female	45	24.23	6.04 (4.53-8.05)^b
		All	56	17.54	6.11 (4.72-7.89)^b
	Daughter	Male	22	5.70	4.63 (3.06-7.02)^b
		Female	109	20.81	5.01 (4.16-6.02)^b
		All	131	14.41	4.93 (4.16-5.83)^b
	All	Male	33	6.36	5.14 (3.67-7.21)^b
		Female	154	21.74	5.28 (4.53-6.17)^b
		All	187	15.24	5.24 (4.55-6.03)^b
Sibling	Brother	Male	10	8.55	11.28 (4.74-26.87)^b
		Female	15	13.93	5.75 (3.48-9.47)^b
		All	25	11.13	7.17 (4.42-11.63)^b
	Sister	Male	15	3.58	6.19 (3.63-10.59)^b
		Female	50	13.25	6.45 (4.39-9.48)^b
		All	65	8.16	6.37 (4.62-8.77)^b
	All	Male	23	4.30	6.96 (4.28-11.32)^b
		Female	65	13.41	6.28 (4.57-8.62)^b
		All	88	8.63	6.43 (4.80-8.62)^b
Twins	Brother	Male	0	0	NA
		Female	0	0	NA
		All	0	0	NA
	Sister	Male	0	0	NA
		Female	4	62.50	25.95 (5.92-113.81)^b
		All	4	45.98	23.03 (5.28-100.45)^b
	All	Male	0	0	NA
		Female	4	58.82	23.45 (5.49-100.12)^b
		All	4	38.10	20.12 (4.86-83.29)^b
Spouse	All	All	75	3.77	2.07 (1.53-2.81)^b

Type of affected relatives	Sex of affected relatives	Sex of individual	No. of NMTC	Prevalence, ‰	Adjusted relative risks^a (95% CIs)
Any	Male	Male	35	4.33	7.61 (4.84-11.97)^b
		Female	86	11.07	5.36 (4.34-6.61)^b
		All	121	7.63	5.84 (4.78-7.13)^b
	Female	Male	86	2.90	5.71 (4.62-7.06)^b
		Female	270	9.50	4.99 (4.23-5.89)^b
		All	356	6.13	5.14 (4.49-5.89)^b
	All	Male	119	3.16	6.07 (4.97-7.40)^b
		Female	354	9.81	5.06 (4.42-5.79)^b
		All	473	6.41	5.27 (4.65-5.97)^b
Parent	Father	Male	14	2.51	6.88 (4.09-11.56)^b
		Female	26	5.37	4.33 (2.91-6.43)^b
		All	40	3.84	4.96 (3.62-6.80)^b
	Mother	Male	49	2.26	6.17 (4.68-8.14)^b
		Female	115	5.92	4.74 (3.94-5.70)^b
		All	164	3.99	5.08 (4.36-5.92)^b
	All	Male	63	2.32	6.33 (4.96-8.07)^b
		Female	141	5.82	4.67 (3.95-5.51)^b
		All	204	3.97	5.07 (4.41-5.81)^b
Offspring	Son	Male	11	8.23	6.56 (3.66-11.78)^b
		Female	45	24.23	6.04 (4.53-8.05)^b
		All	56	17.54	6.11 (4.72-7.89)^b
	Daughter	Male	22	5.70	4.63 (3.06-7.02)^b
		Female	109	20.81	5.01 (4.16-6.02)^b
		All	131	14.41	4.93 (4.16-5.83)^b
	All	Male	33	6.36	5.14 (3.67-7.21)^b
		Female	154	21.74	5.28 (4.53-6.17)^b
		All	187	15.24	5.24 (4.55-6.03)^b
Sibling	Brother	Male	10	8.55	11.28 (4.74-26.87)^b
		Female	15	13.93	5.75 (3.48-9.47)^b
		All	25	11.13	7.17 (4.42-11.63)^b
	Sister	Male	15	3.58	6.19 (3.63-10.59)^b
		Female	50	13.25	6.45 (4.39-9.48)^b
		All	65	8.16	6.37 (4.62-8.77)^b
	All	Male	23	4.30	6.96 (4.28-11.32)^b
		Female	65	13.41	6.28 (4.57-8.62)^b
		All	88	8.63	6.43 (4.80-8.62)^b
Twins	Brother	Male	0	0	NA
		Female	0	0	NA
		All	0	0	NA
	Sister	Male	0	0	NA
		Female	4	62.50	25.95 (5.92-113.81)^b
		All	4	45.98	23.03 (5.28-100.45)^b
	All	Male	0	0	NA
		Female	4	58.82	23.45 (5.49-100.12)^b
		All	4	38.10	20.12 (4.86-83.29)^b
Spouse	All	All	75	3.77	2.07 (1.53-2.81)^b

Abbreviation: NA, not applicable.

^aAdjusted for age, sex, place of residence, quintiles of income level, occupation, and family size.

^bP less than .05.

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