Table 1.

Characteristics of Patients Younger Than 60 Years With Enterovirus CNS Infection and Members of the Comparison Cohort, Denmark, 1997–2016

CharacteristicsPatients with Enterovirus CNS InfectionComparison Cohort
Total174517 450
Male sex, No. (%)995 (57)9950 (57)
Age at study inclusion, median (IQR), y 25 (4–33)25 (4–33)
Age categories, No. (%), y
 0–1349 (20)3490 (20)
 1–20416 (24)4160 (24)
 20–60980 (56)9800 (56)
Danish origin, No. (%)1669 (96)15 860 (91)
Diagnosis before study inclusion, No. (%)
 Cancer 16 (0.9)87 (0.5)
 Epilepsy 31 (1.8)166 (1.0)
 Dementia 1 (0.1)1 (0.0)
 Depression 32 (1.8)221 (1.3)
 F diagnosesa0 (0.0)0 (0.0)
Number of children before study inclusion, median (IQR)b1 (1–2)1 (0–2)
Proportion married the year of study inclusion, No. (%)b508 (52)3716 (38)
Total observation time, yc13 264134 818
Observation time, median (IQR), y5.8 (3.3–12.5)6.2 (3.3–12.6)
Died, No. (%)c19 (1.1)108 (0.6)
Emigrated, No. (%)c60 (3.4)477 (2.7)
Lost to follow-up, No. (%)c0 (0.0)10 (0.1)
CharacteristicsPatients with Enterovirus CNS InfectionComparison Cohort
Total174517 450
Male sex, No. (%)995 (57)9950 (57)
Age at study inclusion, median (IQR), y 25 (4–33)25 (4–33)
Age categories, No. (%), y
 0–1349 (20)3490 (20)
 1–20416 (24)4160 (24)
 20–60980 (56)9800 (56)
Danish origin, No. (%)1669 (96)15 860 (91)
Diagnosis before study inclusion, No. (%)
 Cancer 16 (0.9)87 (0.5)
 Epilepsy 31 (1.8)166 (1.0)
 Dementia 1 (0.1)1 (0.0)
 Depression 32 (1.8)221 (1.3)
 F diagnosesa0 (0.0)0 (0.0)
Number of children before study inclusion, median (IQR)b1 (1–2)1 (0–2)
Proportion married the year of study inclusion, No. (%)b508 (52)3716 (38)
Total observation time, yc13 264134 818
Observation time, median (IQR), y5.8 (3.3–12.5)6.2 (3.3–12.6)
Died, No. (%)c19 (1.1)108 (0.6)
Emigrated, No. (%)c60 (3.4)477 (2.7)
Lost to follow-up, No. (%)c0 (0.0)10 (0.1)

Abbreviations: CNS, central nervous system; IQR, interquartile range.

aRestricted to children younger than 1 year at study inclusion.

bRestricted to individuals aged 20–60 years at time of study inclusion.

cDuring follow-up starting from diagnosis of an enterovirus CNS infection.

Table 1.

Characteristics of Patients Younger Than 60 Years With Enterovirus CNS Infection and Members of the Comparison Cohort, Denmark, 1997–2016

CharacteristicsPatients with Enterovirus CNS InfectionComparison Cohort
Total174517 450
Male sex, No. (%)995 (57)9950 (57)
Age at study inclusion, median (IQR), y 25 (4–33)25 (4–33)
Age categories, No. (%), y
 0–1349 (20)3490 (20)
 1–20416 (24)4160 (24)
 20–60980 (56)9800 (56)
Danish origin, No. (%)1669 (96)15 860 (91)
Diagnosis before study inclusion, No. (%)
 Cancer 16 (0.9)87 (0.5)
 Epilepsy 31 (1.8)166 (1.0)
 Dementia 1 (0.1)1 (0.0)
 Depression 32 (1.8)221 (1.3)
 F diagnosesa0 (0.0)0 (0.0)
Number of children before study inclusion, median (IQR)b1 (1–2)1 (0–2)
Proportion married the year of study inclusion, No. (%)b508 (52)3716 (38)
Total observation time, yc13 264134 818
Observation time, median (IQR), y5.8 (3.3–12.5)6.2 (3.3–12.6)
Died, No. (%)c19 (1.1)108 (0.6)
Emigrated, No. (%)c60 (3.4)477 (2.7)
Lost to follow-up, No. (%)c0 (0.0)10 (0.1)
CharacteristicsPatients with Enterovirus CNS InfectionComparison Cohort
Total174517 450
Male sex, No. (%)995 (57)9950 (57)
Age at study inclusion, median (IQR), y 25 (4–33)25 (4–33)
Age categories, No. (%), y
 0–1349 (20)3490 (20)
 1–20416 (24)4160 (24)
 20–60980 (56)9800 (56)
Danish origin, No. (%)1669 (96)15 860 (91)
Diagnosis before study inclusion, No. (%)
 Cancer 16 (0.9)87 (0.5)
 Epilepsy 31 (1.8)166 (1.0)
 Dementia 1 (0.1)1 (0.0)
 Depression 32 (1.8)221 (1.3)
 F diagnosesa0 (0.0)0 (0.0)
Number of children before study inclusion, median (IQR)b1 (1–2)1 (0–2)
Proportion married the year of study inclusion, No. (%)b508 (52)3716 (38)
Total observation time, yc13 264134 818
Observation time, median (IQR), y5.8 (3.3–12.5)6.2 (3.3–12.6)
Died, No. (%)c19 (1.1)108 (0.6)
Emigrated, No. (%)c60 (3.4)477 (2.7)
Lost to follow-up, No. (%)c0 (0.0)10 (0.1)

Abbreviations: CNS, central nervous system; IQR, interquartile range.

aRestricted to children younger than 1 year at study inclusion.

bRestricted to individuals aged 20–60 years at time of study inclusion.

cDuring follow-up starting from diagnosis of an enterovirus CNS infection.

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