Remaining 10-year risk of local recurrence after breast-preserving surgery followed by postoperative whole-breast irradiation (WBIR) with or without boost RT
| Trial (radiotherapy) . | MFU (year)a . | Local recurrence rate (%) . | P value . | Local recurrence rate (%) . | P value . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Age ≤ 40 . | Age 41–50 . | Age 51–60 . | Grade 3 . | Grade 2 . | Grade 1 . | ||||
| EORTC 22881-10882 (WBI plus boost) | 10 | 13.5 | 8.7 | 4.9 | 0.0014 | 8.6 any age (9.9 < 60 years) | <5 | 0.01 | |
| EBCTCG meta-analysis (WBI) | 10 | 36b | 20.8b | 15b | 0.00001 | 28.6b | 16.4b | 11b | <0.00001 |
| Trial (radiotherapy) . | MFU (year)a . | Local recurrence rate (%) . | P value . | Local recurrence rate (%) . | P value . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Age ≤ 40 . | Age 41–50 . | Age 51–60 . | Grade 3 . | Grade 2 . | Grade 1 . | ||||
| EORTC 22881-10882 (WBI plus boost) | 10 | 13.5 | 8.7 | 4.9 | 0.0014 | 8.6 any age (9.9 < 60 years) | <5 | 0.01 | |
| EBCTCG meta-analysis (WBI) | 10 | 36b | 20.8b | 15b | 0.00001 | 28.6b | 16.4b | 11b | <0.00001 |
aMedian follow-up.
bAny first recurrence: locoregional or distant.
Remaining 10-year risk of local recurrence after breast-preserving surgery followed by postoperative whole-breast irradiation (WBIR) with or without boost RT
| Trial (radiotherapy) . | MFU (year)a . | Local recurrence rate (%) . | P value . | Local recurrence rate (%) . | P value . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Age ≤ 40 . | Age 41–50 . | Age 51–60 . | Grade 3 . | Grade 2 . | Grade 1 . | ||||
| EORTC 22881-10882 (WBI plus boost) | 10 | 13.5 | 8.7 | 4.9 | 0.0014 | 8.6 any age (9.9 < 60 years) | <5 | 0.01 | |
| EBCTCG meta-analysis (WBI) | 10 | 36b | 20.8b | 15b | 0.00001 | 28.6b | 16.4b | 11b | <0.00001 |
| Trial (radiotherapy) . | MFU (year)a . | Local recurrence rate (%) . | P value . | Local recurrence rate (%) . | P value . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Age ≤ 40 . | Age 41–50 . | Age 51–60 . | Grade 3 . | Grade 2 . | Grade 1 . | ||||
| EORTC 22881-10882 (WBI plus boost) | 10 | 13.5 | 8.7 | 4.9 | 0.0014 | 8.6 any age (9.9 < 60 years) | <5 | 0.01 | |
| EBCTCG meta-analysis (WBI) | 10 | 36b | 20.8b | 15b | 0.00001 | 28.6b | 16.4b | 11b | <0.00001 |
aMedian follow-up.
bAny first recurrence: locoregional or distant.
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