Table 1

Subsequent therapy for prostate cancer (intent-to-treat population)

n (%)Japanese subgroupOverall population
AAP (n = 35)Placebo (n = 35)AAP (n = 597)Placebo (n = 602)
Patients eligible for subsequent therapya2133394517
Patients with subsequent therapy for PC18 (85.7)30 (90.9)244 (61.9)355 (68.7)
 Bicalutamide10 (47.6)23 (69.7)57 (14.5)97 (18.8)
 Docetaxel10 (47.6)19 (57.6)144 (36.5)212 (41.0)
 Enzalutamide7 (33.3)23 (69.7)57 (14.5)99 (19.1)
 Cabazitaxel5 (23.8)9 (27.3)25 (6.3)50 (9.7)
 Radium Ra 223 dichloride5 (23.8)6 (18.2)27 (6.9)44 (8.5)
 Dexamethasone2 (9.5)6 (18.2)9 (2.3)16 (3.1)
 Flutamide2 (9.5)7 (21.2)5 (1.3)21 (4.1)
 Abiraterone1 (4.8)12 (36.4)16 (4.1)84 (16.2)
n (%)Japanese subgroupOverall population
AAP (n = 35)Placebo (n = 35)AAP (n = 597)Placebo (n = 602)
Patients eligible for subsequent therapya2133394517
Patients with subsequent therapy for PC18 (85.7)30 (90.9)244 (61.9)355 (68.7)
 Bicalutamide10 (47.6)23 (69.7)57 (14.5)97 (18.8)
 Docetaxel10 (47.6)19 (57.6)144 (36.5)212 (41.0)
 Enzalutamide7 (33.3)23 (69.7)57 (14.5)99 (19.1)
 Cabazitaxel5 (23.8)9 (27.3)25 (6.3)50 (9.7)
 Radium Ra 223 dichloride5 (23.8)6 (18.2)27 (6.9)44 (8.5)
 Dexamethasone2 (9.5)6 (18.2)9 (2.3)16 (3.1)
 Flutamide2 (9.5)7 (21.2)5 (1.3)21 (4.1)
 Abiraterone1 (4.8)12 (36.4)16 (4.1)84 (16.2)

Abbreviations: AAP: abiraterone acetate plus prednisone; n: number of patients and PC: prostate cancer.

a

Patients who discontinued from study treatment and were still alive to receive subsequent therapy by the given clinical cut-off date.

Table 1

Subsequent therapy for prostate cancer (intent-to-treat population)

n (%)Japanese subgroupOverall population
AAP (n = 35)Placebo (n = 35)AAP (n = 597)Placebo (n = 602)
Patients eligible for subsequent therapya2133394517
Patients with subsequent therapy for PC18 (85.7)30 (90.9)244 (61.9)355 (68.7)
 Bicalutamide10 (47.6)23 (69.7)57 (14.5)97 (18.8)
 Docetaxel10 (47.6)19 (57.6)144 (36.5)212 (41.0)
 Enzalutamide7 (33.3)23 (69.7)57 (14.5)99 (19.1)
 Cabazitaxel5 (23.8)9 (27.3)25 (6.3)50 (9.7)
 Radium Ra 223 dichloride5 (23.8)6 (18.2)27 (6.9)44 (8.5)
 Dexamethasone2 (9.5)6 (18.2)9 (2.3)16 (3.1)
 Flutamide2 (9.5)7 (21.2)5 (1.3)21 (4.1)
 Abiraterone1 (4.8)12 (36.4)16 (4.1)84 (16.2)
n (%)Japanese subgroupOverall population
AAP (n = 35)Placebo (n = 35)AAP (n = 597)Placebo (n = 602)
Patients eligible for subsequent therapya2133394517
Patients with subsequent therapy for PC18 (85.7)30 (90.9)244 (61.9)355 (68.7)
 Bicalutamide10 (47.6)23 (69.7)57 (14.5)97 (18.8)
 Docetaxel10 (47.6)19 (57.6)144 (36.5)212 (41.0)
 Enzalutamide7 (33.3)23 (69.7)57 (14.5)99 (19.1)
 Cabazitaxel5 (23.8)9 (27.3)25 (6.3)50 (9.7)
 Radium Ra 223 dichloride5 (23.8)6 (18.2)27 (6.9)44 (8.5)
 Dexamethasone2 (9.5)6 (18.2)9 (2.3)16 (3.1)
 Flutamide2 (9.5)7 (21.2)5 (1.3)21 (4.1)
 Abiraterone1 (4.8)12 (36.4)16 (4.1)84 (16.2)

Abbreviations: AAP: abiraterone acetate plus prednisone; n: number of patients and PC: prostate cancer.

a

Patients who discontinued from study treatment and were still alive to receive subsequent therapy by the given clinical cut-off date.

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