| ID . | Clinical subtype . | Age at death . | Disease duration, years . | Gender . | Cognitive evaluations . | Clinical features related to cognitive impairment . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MI . | Executive dysfunction . | Impaired processing speed . | Personality change . | Disinhibition . | Frontal release signs . | Additional comments . | ||||||
| 1 | FSD | 57 | 8 | Male | – | – | + | – | – | – | – | – |
| 2 | FSD | 60 | 6 | Male | MMSE | – | + | – | + | – | – | – |
| 3 | FSD | 53 | 7 | Male | MMSE, WAIS-R | – | + | + | – | – | – | – |
| 4 | FSD | 66 | 6 | Female | MMSE, WASI-R or III | – | + | – | – | – | – | – |
| 5 | FSD | 70 | 5 | Female | – | – | – | – | + | – | + | – |
| 6 | FSD | 67 | 16 | Male | MMSE, WAIS-III | – | + | – | + | – | + | Impairment of naming ability with semantic errors |
| 7 | FSD | 66 | 8 | Female | WAIS-III | – | + | – | – | – | – | – |
| 8 | FSD | 58 | 5 | Male | MMSE, WAIS-III | – | + | + | + | – | + | – |
| 9 | FSD | 62 | 7 | Female | WAIS-III | – | + | + | – | – | – | – |
| 10 | FSD | 65 | 11 | Male | MMSE | – | + | – | – | – | – | Severe disorientation |
| 11 | FSD | 70 | 10 | Male | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 12 | FSD | 73 | 7 | Female | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 13 | MI | 66 | 3 | Male | – | + | – | – | – | – | – | – |
| 14 | MI | 61 | 9 | Male | – | + | – | – | – | – | – | – |
| 15 | MI | 57 | 4 | Female | – | + | – | – | – | – | – | – |
| 16 | MI | 70 | 6 | Female | – | + | – | – | – | – | – | – |
| 17 | MI | 68 | 9 | Female | MMSE | + | – | – | – | – | – | – |
| 18 | MI | 66 | 22 | Female | – | + | – | – | – | – | – | – |
| 19 | MI+FSD | 64 | 3 | Male | WAIS-III | + | + | – | – | – | – | – |
| 20 | MI+FSD | 63 | 13 | Female | MMSE, WAIS-III, WAIS-R | + | + | + | – | – | – | – |
| 21 | MI+FSD | 63 | 6 | Male | – | + | – | – | + | – | – | – |
| 22 | MI+FSD | 71 | 10 | Male | – | + | + | – | – | – | + | – |
| 23 | MI+FSD | 51 | 7 | Male | – | + | + | – | – | – | – | – |
| 24 | MI+FSD | 70 | 9 | Female | WAIS-III | + | + | + | – | – | – | – |
| 25 | MI+FSD | 71 | 7 | Female | WAIS-III | + | + | – | – | – | + | – |
| 26 | MI+FSD | 70 | 6 | Female | MMSE | + | – | – | – | + | + | – |
| 27 | MI+FSD | 60 | 8 | Male | – | + | + | – | – | + | – | – |
| 28 | MI+FSD | 68 | 8 | Male | MMSE, WAIS-III | + | + | + | – | – | – | – |
| 29 | MI+FSD | 64 | 10 | Male | WAIS-III | + | + | + | – | – | + | – |
| 30 | MI+FSD | 66 | 9 | Female | MMSE | + | + | – | + | – | – | Nominal dysphasia |
| ID . | Clinical subtype . | Age at death . | Disease duration, years . | Gender . | Cognitive evaluations . | Clinical features related to cognitive impairment . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MI . | Executive dysfunction . | Impaired processing speed . | Personality change . | Disinhibition . | Frontal release signs . | Additional comments . | ||||||
| 1 | FSD | 57 | 8 | Male | – | – | + | – | – | – | – | – |
| 2 | FSD | 60 | 6 | Male | MMSE | – | + | – | + | – | – | – |
| 3 | FSD | 53 | 7 | Male | MMSE, WAIS-R | – | + | + | – | – | – | – |
| 4 | FSD | 66 | 6 | Female | MMSE, WASI-R or III | – | + | – | – | – | – | – |
| 5 | FSD | 70 | 5 | Female | – | – | – | – | + | – | + | – |
| 6 | FSD | 67 | 16 | Male | MMSE, WAIS-III | – | + | – | + | – | + | Impairment of naming ability with semantic errors |
| 7 | FSD | 66 | 8 | Female | WAIS-III | – | + | – | – | – | – | – |
| 8 | FSD | 58 | 5 | Male | MMSE, WAIS-III | – | + | + | + | – | + | – |
| 9 | FSD | 62 | 7 | Female | WAIS-III | – | + | + | – | – | – | – |
| 10 | FSD | 65 | 11 | Male | MMSE | – | + | – | – | – | – | Severe disorientation |
| 11 | FSD | 70 | 10 | Male | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 12 | FSD | 73 | 7 | Female | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 13 | MI | 66 | 3 | Male | – | + | – | – | – | – | – | – |
| 14 | MI | 61 | 9 | Male | – | + | – | – | – | – | – | – |
| 15 | MI | 57 | 4 | Female | – | + | – | – | – | – | – | – |
| 16 | MI | 70 | 6 | Female | – | + | – | – | – | – | – | – |
| 17 | MI | 68 | 9 | Female | MMSE | + | – | – | – | – | – | – |
| 18 | MI | 66 | 22 | Female | – | + | – | – | – | – | – | – |
| 19 | MI+FSD | 64 | 3 | Male | WAIS-III | + | + | – | – | – | – | – |
| 20 | MI+FSD | 63 | 13 | Female | MMSE, WAIS-III, WAIS-R | + | + | + | – | – | – | – |
| 21 | MI+FSD | 63 | 6 | Male | – | + | – | – | + | – | – | – |
| 22 | MI+FSD | 71 | 10 | Male | – | + | + | – | – | – | + | – |
| 23 | MI+FSD | 51 | 7 | Male | – | + | + | – | – | – | – | – |
| 24 | MI+FSD | 70 | 9 | Female | WAIS-III | + | + | + | – | – | – | – |
| 25 | MI+FSD | 71 | 7 | Female | WAIS-III | + | + | – | – | – | + | – |
| 26 | MI+FSD | 70 | 6 | Female | MMSE | + | – | – | – | + | + | – |
| 27 | MI+FSD | 60 | 8 | Male | – | + | + | – | – | + | – | – |
| 28 | MI+FSD | 68 | 8 | Male | MMSE, WAIS-III | + | + | + | – | – | – | – |
| 29 | MI+FSD | 64 | 10 | Male | WAIS-III | + | + | + | – | – | + | – |
| 30 | MI+FSD | 66 | 9 | Female | MMSE | + | + | – | + | – | – | Nominal dysphasia |
MI+FSD = memory impairment with FSD; MMSE = Mini-Mental State Examination; WAIS = Wechsler Adult Intelligence Scale.
| ID . | Clinical subtype . | Age at death . | Disease duration, years . | Gender . | Cognitive evaluations . | Clinical features related to cognitive impairment . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MI . | Executive dysfunction . | Impaired processing speed . | Personality change . | Disinhibition . | Frontal release signs . | Additional comments . | ||||||
| 1 | FSD | 57 | 8 | Male | – | – | + | – | – | – | – | – |
| 2 | FSD | 60 | 6 | Male | MMSE | – | + | – | + | – | – | – |
| 3 | FSD | 53 | 7 | Male | MMSE, WAIS-R | – | + | + | – | – | – | – |
| 4 | FSD | 66 | 6 | Female | MMSE, WASI-R or III | – | + | – | – | – | – | – |
| 5 | FSD | 70 | 5 | Female | – | – | – | – | + | – | + | – |
| 6 | FSD | 67 | 16 | Male | MMSE, WAIS-III | – | + | – | + | – | + | Impairment of naming ability with semantic errors |
| 7 | FSD | 66 | 8 | Female | WAIS-III | – | + | – | – | – | – | – |
| 8 | FSD | 58 | 5 | Male | MMSE, WAIS-III | – | + | + | + | – | + | – |
| 9 | FSD | 62 | 7 | Female | WAIS-III | – | + | + | – | – | – | – |
| 10 | FSD | 65 | 11 | Male | MMSE | – | + | – | – | – | – | Severe disorientation |
| 11 | FSD | 70 | 10 | Male | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 12 | FSD | 73 | 7 | Female | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 13 | MI | 66 | 3 | Male | – | + | – | – | – | – | – | – |
| 14 | MI | 61 | 9 | Male | – | + | – | – | – | – | – | – |
| 15 | MI | 57 | 4 | Female | – | + | – | – | – | – | – | – |
| 16 | MI | 70 | 6 | Female | – | + | – | – | – | – | – | – |
| 17 | MI | 68 | 9 | Female | MMSE | + | – | – | – | – | – | – |
| 18 | MI | 66 | 22 | Female | – | + | – | – | – | – | – | – |
| 19 | MI+FSD | 64 | 3 | Male | WAIS-III | + | + | – | – | – | – | – |
| 20 | MI+FSD | 63 | 13 | Female | MMSE, WAIS-III, WAIS-R | + | + | + | – | – | – | – |
| 21 | MI+FSD | 63 | 6 | Male | – | + | – | – | + | – | – | – |
| 22 | MI+FSD | 71 | 10 | Male | – | + | + | – | – | – | + | – |
| 23 | MI+FSD | 51 | 7 | Male | – | + | + | – | – | – | – | – |
| 24 | MI+FSD | 70 | 9 | Female | WAIS-III | + | + | + | – | – | – | – |
| 25 | MI+FSD | 71 | 7 | Female | WAIS-III | + | + | – | – | – | + | – |
| 26 | MI+FSD | 70 | 6 | Female | MMSE | + | – | – | – | + | + | – |
| 27 | MI+FSD | 60 | 8 | Male | – | + | + | – | – | + | – | – |
| 28 | MI+FSD | 68 | 8 | Male | MMSE, WAIS-III | + | + | + | – | – | – | – |
| 29 | MI+FSD | 64 | 10 | Male | WAIS-III | + | + | + | – | – | + | – |
| 30 | MI+FSD | 66 | 9 | Female | MMSE | + | + | – | + | – | – | Nominal dysphasia |
| ID . | Clinical subtype . | Age at death . | Disease duration, years . | Gender . | Cognitive evaluations . | Clinical features related to cognitive impairment . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MI . | Executive dysfunction . | Impaired processing speed . | Personality change . | Disinhibition . | Frontal release signs . | Additional comments . | ||||||
| 1 | FSD | 57 | 8 | Male | – | – | + | – | – | – | – | – |
| 2 | FSD | 60 | 6 | Male | MMSE | – | + | – | + | – | – | – |
| 3 | FSD | 53 | 7 | Male | MMSE, WAIS-R | – | + | + | – | – | – | – |
| 4 | FSD | 66 | 6 | Female | MMSE, WASI-R or III | – | + | – | – | – | – | – |
| 5 | FSD | 70 | 5 | Female | – | – | – | – | + | – | + | – |
| 6 | FSD | 67 | 16 | Male | MMSE, WAIS-III | – | + | – | + | – | + | Impairment of naming ability with semantic errors |
| 7 | FSD | 66 | 8 | Female | WAIS-III | – | + | – | – | – | – | – |
| 8 | FSD | 58 | 5 | Male | MMSE, WAIS-III | – | + | + | + | – | + | – |
| 9 | FSD | 62 | 7 | Female | WAIS-III | – | + | + | – | – | – | – |
| 10 | FSD | 65 | 11 | Male | MMSE | – | + | – | – | – | – | Severe disorientation |
| 11 | FSD | 70 | 10 | Male | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 12 | FSD | 73 | 7 | Female | – | – | – | – | – | – | – | Documentation of significant cognitive decline only |
| 13 | MI | 66 | 3 | Male | – | + | – | – | – | – | – | – |
| 14 | MI | 61 | 9 | Male | – | + | – | – | – | – | – | – |
| 15 | MI | 57 | 4 | Female | – | + | – | – | – | – | – | – |
| 16 | MI | 70 | 6 | Female | – | + | – | – | – | – | – | – |
| 17 | MI | 68 | 9 | Female | MMSE | + | – | – | – | – | – | – |
| 18 | MI | 66 | 22 | Female | – | + | – | – | – | – | – | – |
| 19 | MI+FSD | 64 | 3 | Male | WAIS-III | + | + | – | – | – | – | – |
| 20 | MI+FSD | 63 | 13 | Female | MMSE, WAIS-III, WAIS-R | + | + | + | – | – | – | – |
| 21 | MI+FSD | 63 | 6 | Male | – | + | – | – | + | – | – | – |
| 22 | MI+FSD | 71 | 10 | Male | – | + | + | – | – | – | + | – |
| 23 | MI+FSD | 51 | 7 | Male | – | + | + | – | – | – | – | – |
| 24 | MI+FSD | 70 | 9 | Female | WAIS-III | + | + | + | – | – | – | – |
| 25 | MI+FSD | 71 | 7 | Female | WAIS-III | + | + | – | – | – | + | – |
| 26 | MI+FSD | 70 | 6 | Female | MMSE | + | – | – | – | + | + | – |
| 27 | MI+FSD | 60 | 8 | Male | – | + | + | – | – | + | – | – |
| 28 | MI+FSD | 68 | 8 | Male | MMSE, WAIS-III | + | + | + | – | – | – | – |
| 29 | MI+FSD | 64 | 10 | Male | WAIS-III | + | + | + | – | – | + | – |
| 30 | MI+FSD | 66 | 9 | Female | MMSE | + | + | – | + | – | – | Nominal dysphasia |
MI+FSD = memory impairment with FSD; MMSE = Mini-Mental State Examination; WAIS = Wechsler Adult Intelligence Scale.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
