Comparison of the Results of Antibody Detection in Patients With Coronavirus Disease 2019 According to Days Post–Disease Onset
| IgM . | IgG . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | < 10 d . | . | . | 10–19 d . | . | . | 20–29 d . | . | . | 30–39 d . | . | . | 40–49 d . | . | . | Sum . | . | . |
| . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . |
| (+), No. | 4 | 1 | 5 | 5 | 0 | 5 | 17 | 0 | 17 | 27 | 0 | 27 | 4 | 0 | 4 | 58 | 1 | 59 |
| (–), No. | 0 | 2 | 2 | 3 | 2 | 5 | 21 | 0 | 21 | 19 | 3 | 22 | 4 | 0 | 4 | 46 | 7 | 53 |
| Total No. | 4 | 3 | 7 | 8 | 2 | 10 | 38 | 0 | 38 | 46 | 3 | 49 | 8 | 0 | 8 | 104 | 8 | 112 |
| IgM titer, AU/mL | 17.65 ± 18.40 | 14.98 ± 21.85a | 10.89 ± 9.34a | 28.99 ± 64.12a | 27.03 ± 17.35a | 20.93 ± 45.94 | ||||||||||||
| IgG titer, AU/mL | 31.53 ± 51.33 | 76.81 ± 63.59a | 126.54 ± 44.80b | 130.19 ± 63.57c | 165.46 ± 18.92d | 122.26 ± 60.94 |
| IgM . | IgG . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | < 10 d . | . | . | 10–19 d . | . | . | 20–29 d . | . | . | 30–39 d . | . | . | 40–49 d . | . | . | Sum . | . | . |
| . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . |
| (+), No. | 4 | 1 | 5 | 5 | 0 | 5 | 17 | 0 | 17 | 27 | 0 | 27 | 4 | 0 | 4 | 58 | 1 | 59 |
| (–), No. | 0 | 2 | 2 | 3 | 2 | 5 | 21 | 0 | 21 | 19 | 3 | 22 | 4 | 0 | 4 | 46 | 7 | 53 |
| Total No. | 4 | 3 | 7 | 8 | 2 | 10 | 38 | 0 | 38 | 46 | 3 | 49 | 8 | 0 | 8 | 104 | 8 | 112 |
| IgM titer, AU/mL | 17.65 ± 18.40 | 14.98 ± 21.85a | 10.89 ± 9.34a | 28.99 ± 64.12a | 27.03 ± 17.35a | 20.93 ± 45.94 | ||||||||||||
| IgG titer, AU/mL | 31.53 ± 51.33 | 76.81 ± 63.59a | 126.54 ± 44.80b | 130.19 ± 63.57c | 165.46 ± 18.92d | 122.26 ± 60.94 |
Data represent mean ± standard deviation unless otherwise indicated.
Abbreviations: IgG, immunoglobulin G; IgM, immunoglobulin M.
aCompared to the IgM and IgG titer in patients < 10 days after coronavirus disease 2019 onset, no statistical difference was shown.
b–dCompared to the IgM and IgG titer in patients < 10 days after coronavirus disease 2019 onset, there is a significant difference of IgG titer in patients’ disease onset at 20–29 days (P = .0025b), 30–39 days (P = .0147c), and > 40 days (P = .0049d), respectively. The rest showed no statistical difference in other subgroups.
Comparison of the Results of Antibody Detection in Patients With Coronavirus Disease 2019 According to Days Post–Disease Onset
| IgM . | IgG . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | < 10 d . | . | . | 10–19 d . | . | . | 20–29 d . | . | . | 30–39 d . | . | . | 40–49 d . | . | . | Sum . | . | . |
| . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . |
| (+), No. | 4 | 1 | 5 | 5 | 0 | 5 | 17 | 0 | 17 | 27 | 0 | 27 | 4 | 0 | 4 | 58 | 1 | 59 |
| (–), No. | 0 | 2 | 2 | 3 | 2 | 5 | 21 | 0 | 21 | 19 | 3 | 22 | 4 | 0 | 4 | 46 | 7 | 53 |
| Total No. | 4 | 3 | 7 | 8 | 2 | 10 | 38 | 0 | 38 | 46 | 3 | 49 | 8 | 0 | 8 | 104 | 8 | 112 |
| IgM titer, AU/mL | 17.65 ± 18.40 | 14.98 ± 21.85a | 10.89 ± 9.34a | 28.99 ± 64.12a | 27.03 ± 17.35a | 20.93 ± 45.94 | ||||||||||||
| IgG titer, AU/mL | 31.53 ± 51.33 | 76.81 ± 63.59a | 126.54 ± 44.80b | 130.19 ± 63.57c | 165.46 ± 18.92d | 122.26 ± 60.94 |
| IgM . | IgG . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | < 10 d . | . | . | 10–19 d . | . | . | 20–29 d . | . | . | 30–39 d . | . | . | 40–49 d . | . | . | Sum . | . | . |
| . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . | (+) . | (–) . | Total . |
| (+), No. | 4 | 1 | 5 | 5 | 0 | 5 | 17 | 0 | 17 | 27 | 0 | 27 | 4 | 0 | 4 | 58 | 1 | 59 |
| (–), No. | 0 | 2 | 2 | 3 | 2 | 5 | 21 | 0 | 21 | 19 | 3 | 22 | 4 | 0 | 4 | 46 | 7 | 53 |
| Total No. | 4 | 3 | 7 | 8 | 2 | 10 | 38 | 0 | 38 | 46 | 3 | 49 | 8 | 0 | 8 | 104 | 8 | 112 |
| IgM titer, AU/mL | 17.65 ± 18.40 | 14.98 ± 21.85a | 10.89 ± 9.34a | 28.99 ± 64.12a | 27.03 ± 17.35a | 20.93 ± 45.94 | ||||||||||||
| IgG titer, AU/mL | 31.53 ± 51.33 | 76.81 ± 63.59a | 126.54 ± 44.80b | 130.19 ± 63.57c | 165.46 ± 18.92d | 122.26 ± 60.94 |
Data represent mean ± standard deviation unless otherwise indicated.
Abbreviations: IgG, immunoglobulin G; IgM, immunoglobulin M.
aCompared to the IgM and IgG titer in patients < 10 days after coronavirus disease 2019 onset, no statistical difference was shown.
b–dCompared to the IgM and IgG titer in patients < 10 days after coronavirus disease 2019 onset, there is a significant difference of IgG titer in patients’ disease onset at 20–29 days (P = .0025b), 30–39 days (P = .0147c), and > 40 days (P = .0049d), respectively. The rest showed no statistical difference in other subgroups.
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