Table 1.

Characteristics of Study Populationa

Characteristics PWH (n = 587)Controls (n = 587)
Age, years, median (IQR)52 (47–60)52 (47–60)
Sex, male, n (%)518 (88)518 (88)
Body mass index (BMI), kg/m2, mean (SD)24.8 (3.5)26.6 (3.5)
Smoking Status, n (%)
 Never smoker196 (34)261 (45)
 Former smoker222 (39)240 (41)
 Current smoker 157 (27)82 (14)
Physical Activity, n (%)
 Active317 (54)327 (56)
 Mildly active193 (33)222 (38)
 Sedentary 48 (8.2)36 (6.1)
Hypertension, n (%) 272 (46)368 (63)
Diabetes, n (%) 18 (3.1)18 (3.1)
Dyslipidemia, n (%)128 (22)191 (33)
Lipid-lowering treatment, n (%)79 (13)64 (11)
LDL, mmol/L, mean (SD)2.9 (1.0)3.5 (.9)
Framingham risk score, median (IQR)12.8 (7.1–21.5)13.2 (8.2–23.1)
Characteristics PWH (n = 587)Controls (n = 587)
Age, years, median (IQR)52 (47–60)52 (47–60)
Sex, male, n (%)518 (88)518 (88)
Body mass index (BMI), kg/m2, mean (SD)24.8 (3.5)26.6 (3.5)
Smoking Status, n (%)
 Never smoker196 (34)261 (45)
 Former smoker222 (39)240 (41)
 Current smoker 157 (27)82 (14)
Physical Activity, n (%)
 Active317 (54)327 (56)
 Mildly active193 (33)222 (38)
 Sedentary 48 (8.2)36 (6.1)
Hypertension, n (%) 272 (46)368 (63)
Diabetes, n (%) 18 (3.1)18 (3.1)
Dyslipidemia, n (%)128 (22)191 (33)
Lipid-lowering treatment, n (%)79 (13)64 (11)
LDL, mmol/L, mean (SD)2.9 (1.0)3.5 (.9)
Framingham risk score, median (IQR)12.8 (7.1–21.5)13.2 (8.2–23.1)

Abbreviations: BMI, body mass index; HIV, human immunodeficiency virus; IQR, interquartile range; LDL, low-density lipoprotein; PWH, persons with HIV; SD, standard deviation.

aHypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg and/or antihypertensive treatment. Dyslipidemia was defined as LDL ≥4.16 mmol/L (160 mg/dL) and/or lipid-lowering treatment. Diabetes was defined as nonfasting venous plasma glucose ≥11.1 mmol/L or HbA1c ≥6.5% or treatment with antidiabetic drug for type II diabetes. Physical activity was grouped as sedentary if active less than 2 hours/week, mildly active if active 2–4 hours/week, or active if active more than 4 hours/week or strenuous exercise 2–4 hours a week. If numbers and percentages do not add up, it is due to missing values. Framingham risk score was calculated for those 40–74 years of age.

Table 1.

Characteristics of Study Populationa

Characteristics PWH (n = 587)Controls (n = 587)
Age, years, median (IQR)52 (47–60)52 (47–60)
Sex, male, n (%)518 (88)518 (88)
Body mass index (BMI), kg/m2, mean (SD)24.8 (3.5)26.6 (3.5)
Smoking Status, n (%)
 Never smoker196 (34)261 (45)
 Former smoker222 (39)240 (41)
 Current smoker 157 (27)82 (14)
Physical Activity, n (%)
 Active317 (54)327 (56)
 Mildly active193 (33)222 (38)
 Sedentary 48 (8.2)36 (6.1)
Hypertension, n (%) 272 (46)368 (63)
Diabetes, n (%) 18 (3.1)18 (3.1)
Dyslipidemia, n (%)128 (22)191 (33)
Lipid-lowering treatment, n (%)79 (13)64 (11)
LDL, mmol/L, mean (SD)2.9 (1.0)3.5 (.9)
Framingham risk score, median (IQR)12.8 (7.1–21.5)13.2 (8.2–23.1)
Characteristics PWH (n = 587)Controls (n = 587)
Age, years, median (IQR)52 (47–60)52 (47–60)
Sex, male, n (%)518 (88)518 (88)
Body mass index (BMI), kg/m2, mean (SD)24.8 (3.5)26.6 (3.5)
Smoking Status, n (%)
 Never smoker196 (34)261 (45)
 Former smoker222 (39)240 (41)
 Current smoker 157 (27)82 (14)
Physical Activity, n (%)
 Active317 (54)327 (56)
 Mildly active193 (33)222 (38)
 Sedentary 48 (8.2)36 (6.1)
Hypertension, n (%) 272 (46)368 (63)
Diabetes, n (%) 18 (3.1)18 (3.1)
Dyslipidemia, n (%)128 (22)191 (33)
Lipid-lowering treatment, n (%)79 (13)64 (11)
LDL, mmol/L, mean (SD)2.9 (1.0)3.5 (.9)
Framingham risk score, median (IQR)12.8 (7.1–21.5)13.2 (8.2–23.1)

Abbreviations: BMI, body mass index; HIV, human immunodeficiency virus; IQR, interquartile range; LDL, low-density lipoprotein; PWH, persons with HIV; SD, standard deviation.

aHypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg and/or antihypertensive treatment. Dyslipidemia was defined as LDL ≥4.16 mmol/L (160 mg/dL) and/or lipid-lowering treatment. Diabetes was defined as nonfasting venous plasma glucose ≥11.1 mmol/L or HbA1c ≥6.5% or treatment with antidiabetic drug for type II diabetes. Physical activity was grouped as sedentary if active less than 2 hours/week, mildly active if active 2–4 hours/week, or active if active more than 4 hours/week or strenuous exercise 2–4 hours a week. If numbers and percentages do not add up, it is due to missing values. Framingham risk score was calculated for those 40–74 years of age.

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