Table 1.

Criteria Used to Define Frailty in the SJLIFE Cohort

Frailty ComponentSJLIFE Criteria (Reference)
Decreased lean muscle massLean muscle mass by dual x-ray absorptiometry below −1 age- and sex-specific SD when compared with data from a national sample (NHANES) (16)
Decreased vitalityScore ≤40 (1 SD, based on a standard normal distribution; this represents approximately the lowest 6.7% of the general population) on the Vitality Subscale of the Medical Outcomes Survey Short Form 36 (16).
Poor physical activityExpended <383 Kcal/wk (males) or <270 Kcal/wk (females) during leisure time physical activity based on the NHANES Physical Activity Questionnaire (18, 19).
Walking speed (slowness)Females <159 and males <173 centimeters tall were classified as slow if they took ≥7 seconds, and females ≥159 and males ≥173 centimeters tall were classified as slow if they took ≥6 seconds to walk 15 feet at their usual pace (20).
Hand grip strength (weakness)Hand grip strength stratified by body mass index and sex (20).
MalesFemales
BMICut PointBMICut Point
≤ 24 kg/m2≤29 kg≤ 23 kg/m2≤17 kg
24.1–26 kg/m2≤30 kg23.1–26 kg/m2≤17.3 kg
26.1–28 kg/m2≤30 kg26.1–29 kg/m2≤18 kg
> 28 kg/m2≤32 kg> 29 kg/m2≤21 kg
Frailty ComponentSJLIFE Criteria (Reference)
Decreased lean muscle massLean muscle mass by dual x-ray absorptiometry below −1 age- and sex-specific SD when compared with data from a national sample (NHANES) (16)
Decreased vitalityScore ≤40 (1 SD, based on a standard normal distribution; this represents approximately the lowest 6.7% of the general population) on the Vitality Subscale of the Medical Outcomes Survey Short Form 36 (16).
Poor physical activityExpended <383 Kcal/wk (males) or <270 Kcal/wk (females) during leisure time physical activity based on the NHANES Physical Activity Questionnaire (18, 19).
Walking speed (slowness)Females <159 and males <173 centimeters tall were classified as slow if they took ≥7 seconds, and females ≥159 and males ≥173 centimeters tall were classified as slow if they took ≥6 seconds to walk 15 feet at their usual pace (20).
Hand grip strength (weakness)Hand grip strength stratified by body mass index and sex (20).
MalesFemales
BMICut PointBMICut Point
≤ 24 kg/m2≤29 kg≤ 23 kg/m2≤17 kg
24.1–26 kg/m2≤30 kg23.1–26 kg/m2≤17.3 kg
26.1–28 kg/m2≤30 kg26.1–29 kg/m2≤18 kg
> 28 kg/m2≤32 kg> 29 kg/m2≤21 kg

Abbreviations: BMI, body mass index; NHANES, National Health and Nutrition Examination Survey.

Table 1.

Criteria Used to Define Frailty in the SJLIFE Cohort

Frailty ComponentSJLIFE Criteria (Reference)
Decreased lean muscle massLean muscle mass by dual x-ray absorptiometry below −1 age- and sex-specific SD when compared with data from a national sample (NHANES) (16)
Decreased vitalityScore ≤40 (1 SD, based on a standard normal distribution; this represents approximately the lowest 6.7% of the general population) on the Vitality Subscale of the Medical Outcomes Survey Short Form 36 (16).
Poor physical activityExpended <383 Kcal/wk (males) or <270 Kcal/wk (females) during leisure time physical activity based on the NHANES Physical Activity Questionnaire (18, 19).
Walking speed (slowness)Females <159 and males <173 centimeters tall were classified as slow if they took ≥7 seconds, and females ≥159 and males ≥173 centimeters tall were classified as slow if they took ≥6 seconds to walk 15 feet at their usual pace (20).
Hand grip strength (weakness)Hand grip strength stratified by body mass index and sex (20).
MalesFemales
BMICut PointBMICut Point
≤ 24 kg/m2≤29 kg≤ 23 kg/m2≤17 kg
24.1–26 kg/m2≤30 kg23.1–26 kg/m2≤17.3 kg
26.1–28 kg/m2≤30 kg26.1–29 kg/m2≤18 kg
> 28 kg/m2≤32 kg> 29 kg/m2≤21 kg
Frailty ComponentSJLIFE Criteria (Reference)
Decreased lean muscle massLean muscle mass by dual x-ray absorptiometry below −1 age- and sex-specific SD when compared with data from a national sample (NHANES) (16)
Decreased vitalityScore ≤40 (1 SD, based on a standard normal distribution; this represents approximately the lowest 6.7% of the general population) on the Vitality Subscale of the Medical Outcomes Survey Short Form 36 (16).
Poor physical activityExpended <383 Kcal/wk (males) or <270 Kcal/wk (females) during leisure time physical activity based on the NHANES Physical Activity Questionnaire (18, 19).
Walking speed (slowness)Females <159 and males <173 centimeters tall were classified as slow if they took ≥7 seconds, and females ≥159 and males ≥173 centimeters tall were classified as slow if they took ≥6 seconds to walk 15 feet at their usual pace (20).
Hand grip strength (weakness)Hand grip strength stratified by body mass index and sex (20).
MalesFemales
BMICut PointBMICut Point
≤ 24 kg/m2≤29 kg≤ 23 kg/m2≤17 kg
24.1–26 kg/m2≤30 kg23.1–26 kg/m2≤17.3 kg
26.1–28 kg/m2≤30 kg26.1–29 kg/m2≤18 kg
> 28 kg/m2≤32 kg> 29 kg/m2≤21 kg

Abbreviations: BMI, body mass index; NHANES, National Health and Nutrition Examination Survey.

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