Table 2.

Arboviral Serostatus of 17D Vaccinees

DENV Immune StatusaZIKV Immune StatusbCHIKV Immune Statusc
NaivePositiveNaivePositive
Naive57525534
DENV198190
DENV211101110
DENV376161
DENV422020
Secondary66060
Total92848875
DENV Immune StatusaZIKV Immune StatusbCHIKV Immune Statusc
NaivePositiveNaivePositive
Naive57525534
DENV198190
DENV211101110
DENV376161
DENV422020
Secondary66060
Total92848875

Abbreviations: CHIKV, chikungunya virus; DENV, dengue virus; PRNT50, 50 percent plaque reduction neutralization test; ZIKV, Zika virus.

aSubjects with PRNT50 ≥1:20 against only 1 serotype or with a PRNT50 against 1 serotype that was 4-fold higher than the other serotype were classified as primary for the highest titer serotype. All other DENV seropositive subjects were classified as secondary.

bSubjects with PRNT50 ≥1:20 against ZIKV were classified as ZIKV positive.

cSubjects with PRNT90 ≥1:20 against CHIKV were classified as CHIKV positive.

Table 2.

Arboviral Serostatus of 17D Vaccinees

DENV Immune StatusaZIKV Immune StatusbCHIKV Immune Statusc
NaivePositiveNaivePositive
Naive57525534
DENV198190
DENV211101110
DENV376161
DENV422020
Secondary66060
Total92848875
DENV Immune StatusaZIKV Immune StatusbCHIKV Immune Statusc
NaivePositiveNaivePositive
Naive57525534
DENV198190
DENV211101110
DENV376161
DENV422020
Secondary66060
Total92848875

Abbreviations: CHIKV, chikungunya virus; DENV, dengue virus; PRNT50, 50 percent plaque reduction neutralization test; ZIKV, Zika virus.

aSubjects with PRNT50 ≥1:20 against only 1 serotype or with a PRNT50 against 1 serotype that was 4-fold higher than the other serotype were classified as primary for the highest titer serotype. All other DENV seropositive subjects were classified as secondary.

bSubjects with PRNT50 ≥1:20 against ZIKV were classified as ZIKV positive.

cSubjects with PRNT90 ≥1:20 against CHIKV were classified as CHIKV positive.

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