Table 1.

Baseline Characteristics

VariableAnalysis 1: All Pregnancies in 2007–2017, No. (%)Analysis 2: Pregnancy Intervals Starting in 2007–2017, No. (%)
Women evaluated, no. (%)1 042 647 (100.0)697 456 (100.0)
Age group, y
 15–19130 808 (12.6)107 842 (15.5)
 20–24288 543 (27.7)204 837 (29.4)
 25–29285 297 (27.4)177 778 (25.5)
 30–34199 201 (19.1)119 158 (17.1)
 35–39102 833 (9.9)64 044 (9.2)
 40–4431 851 (3.1)21 123 (3.0)
 45–494114 (0.4)2674 (0.4)
HIV status, ART status
 Negative/undiagnosed866 587 (83.1)568 706 (81.5)
 Positive, ART-naivea71 289 (6.8)74 656 (10.7)
 Positive, ART-experienced104 771 (10.0)54 094 (7.8)
Pregnancy outcome
 Live birth600 398 (57.6)372 653 (53.4)
 Stillbirth13 521 (1.3)8506 (1.2)
 Neonatal death6294 (0.6)3628 (0.5)
 Miscarriage14 319 (1.4)7401 (1.1)
 Induced abortion30 463 (2.9)15 881 (2.3)
 Unspecified/ambiguous377 652 (36.2)289 387 (41.5)
Population group
 Mixed race457 525 (43.9)301 018 (43.2)
 Black African493 304 (47.3)322 171 (46.2)
 White37 487 (3.6)28 976 (4.2)
 Other/unspecified54 331 (5.2)45 291 (6.5)
Year
 200759 315 (5.7)55 228 (7.9)
 200893 186 (8.9)86 333 (12.4)
 200985 843 (8.2)75 671 (10.9)
 201077 638 (7.5)63 086 (9.1)
 201174 972 (7.2)56 744 (8.1)
 201279 056 (7.6)56 115 (8.1)
 201392 851 (8.9)62 785 (9.0)
 2014106 744 (10.2)69 952 (10.0)
 2015118 672 (11.4)76 335 (10.9)
 2016121 435 (11.7)75 034 (10.8)
 2017132 935 (12.8)20 173 (2.9)
VariableAnalysis 1: All Pregnancies in 2007–2017, No. (%)Analysis 2: Pregnancy Intervals Starting in 2007–2017, No. (%)
Women evaluated, no. (%)1 042 647 (100.0)697 456 (100.0)
Age group, y
 15–19130 808 (12.6)107 842 (15.5)
 20–24288 543 (27.7)204 837 (29.4)
 25–29285 297 (27.4)177 778 (25.5)
 30–34199 201 (19.1)119 158 (17.1)
 35–39102 833 (9.9)64 044 (9.2)
 40–4431 851 (3.1)21 123 (3.0)
 45–494114 (0.4)2674 (0.4)
HIV status, ART status
 Negative/undiagnosed866 587 (83.1)568 706 (81.5)
 Positive, ART-naivea71 289 (6.8)74 656 (10.7)
 Positive, ART-experienced104 771 (10.0)54 094 (7.8)
Pregnancy outcome
 Live birth600 398 (57.6)372 653 (53.4)
 Stillbirth13 521 (1.3)8506 (1.2)
 Neonatal death6294 (0.6)3628 (0.5)
 Miscarriage14 319 (1.4)7401 (1.1)
 Induced abortion30 463 (2.9)15 881 (2.3)
 Unspecified/ambiguous377 652 (36.2)289 387 (41.5)
Population group
 Mixed race457 525 (43.9)301 018 (43.2)
 Black African493 304 (47.3)322 171 (46.2)
 White37 487 (3.6)28 976 (4.2)
 Other/unspecified54 331 (5.2)45 291 (6.5)
Year
 200759 315 (5.7)55 228 (7.9)
 200893 186 (8.9)86 333 (12.4)
 200985 843 (8.2)75 671 (10.9)
 201077 638 (7.5)63 086 (9.1)
 201174 972 (7.2)56 744 (8.1)
 201279 056 (7.6)56 115 (8.1)
 201392 851 (8.9)62 785 (9.0)
 2014106 744 (10.2)69 952 (10.0)
 2015118 672 (11.4)76 335 (10.9)
 2016121 435 (11.7)75 034 (10.8)
 2017132 935 (12.8)20 173 (2.9)

For analysis 1, characteristics of all pregnancies in the database are presented. For analysis 2, characteristics are presented only for the index pregnancy (ie, the first pregnancy in the database), and we exclude HIV-positive women with no CD4+ T-cell count measurements and women whose estimated pregnancy end date is after the end of 2017.

Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus.

aIn analysis 1, pregnancies are only classified as involving HIV-positive women if there is evidence of HIV before the pregnancy outcome date; in analysis 2, pregnancy intervals are classified as HIV positive if there is any evidence of HIV (ie, evidence before or after the index pregnancy outcome date).

Table 1.

Baseline Characteristics

VariableAnalysis 1: All Pregnancies in 2007–2017, No. (%)Analysis 2: Pregnancy Intervals Starting in 2007–2017, No. (%)
Women evaluated, no. (%)1 042 647 (100.0)697 456 (100.0)
Age group, y
 15–19130 808 (12.6)107 842 (15.5)
 20–24288 543 (27.7)204 837 (29.4)
 25–29285 297 (27.4)177 778 (25.5)
 30–34199 201 (19.1)119 158 (17.1)
 35–39102 833 (9.9)64 044 (9.2)
 40–4431 851 (3.1)21 123 (3.0)
 45–494114 (0.4)2674 (0.4)
HIV status, ART status
 Negative/undiagnosed866 587 (83.1)568 706 (81.5)
 Positive, ART-naivea71 289 (6.8)74 656 (10.7)
 Positive, ART-experienced104 771 (10.0)54 094 (7.8)
Pregnancy outcome
 Live birth600 398 (57.6)372 653 (53.4)
 Stillbirth13 521 (1.3)8506 (1.2)
 Neonatal death6294 (0.6)3628 (0.5)
 Miscarriage14 319 (1.4)7401 (1.1)
 Induced abortion30 463 (2.9)15 881 (2.3)
 Unspecified/ambiguous377 652 (36.2)289 387 (41.5)
Population group
 Mixed race457 525 (43.9)301 018 (43.2)
 Black African493 304 (47.3)322 171 (46.2)
 White37 487 (3.6)28 976 (4.2)
 Other/unspecified54 331 (5.2)45 291 (6.5)
Year
 200759 315 (5.7)55 228 (7.9)
 200893 186 (8.9)86 333 (12.4)
 200985 843 (8.2)75 671 (10.9)
 201077 638 (7.5)63 086 (9.1)
 201174 972 (7.2)56 744 (8.1)
 201279 056 (7.6)56 115 (8.1)
 201392 851 (8.9)62 785 (9.0)
 2014106 744 (10.2)69 952 (10.0)
 2015118 672 (11.4)76 335 (10.9)
 2016121 435 (11.7)75 034 (10.8)
 2017132 935 (12.8)20 173 (2.9)
VariableAnalysis 1: All Pregnancies in 2007–2017, No. (%)Analysis 2: Pregnancy Intervals Starting in 2007–2017, No. (%)
Women evaluated, no. (%)1 042 647 (100.0)697 456 (100.0)
Age group, y
 15–19130 808 (12.6)107 842 (15.5)
 20–24288 543 (27.7)204 837 (29.4)
 25–29285 297 (27.4)177 778 (25.5)
 30–34199 201 (19.1)119 158 (17.1)
 35–39102 833 (9.9)64 044 (9.2)
 40–4431 851 (3.1)21 123 (3.0)
 45–494114 (0.4)2674 (0.4)
HIV status, ART status
 Negative/undiagnosed866 587 (83.1)568 706 (81.5)
 Positive, ART-naivea71 289 (6.8)74 656 (10.7)
 Positive, ART-experienced104 771 (10.0)54 094 (7.8)
Pregnancy outcome
 Live birth600 398 (57.6)372 653 (53.4)
 Stillbirth13 521 (1.3)8506 (1.2)
 Neonatal death6294 (0.6)3628 (0.5)
 Miscarriage14 319 (1.4)7401 (1.1)
 Induced abortion30 463 (2.9)15 881 (2.3)
 Unspecified/ambiguous377 652 (36.2)289 387 (41.5)
Population group
 Mixed race457 525 (43.9)301 018 (43.2)
 Black African493 304 (47.3)322 171 (46.2)
 White37 487 (3.6)28 976 (4.2)
 Other/unspecified54 331 (5.2)45 291 (6.5)
Year
 200759 315 (5.7)55 228 (7.9)
 200893 186 (8.9)86 333 (12.4)
 200985 843 (8.2)75 671 (10.9)
 201077 638 (7.5)63 086 (9.1)
 201174 972 (7.2)56 744 (8.1)
 201279 056 (7.6)56 115 (8.1)
 201392 851 (8.9)62 785 (9.0)
 2014106 744 (10.2)69 952 (10.0)
 2015118 672 (11.4)76 335 (10.9)
 2016121 435 (11.7)75 034 (10.8)
 2017132 935 (12.8)20 173 (2.9)

For analysis 1, characteristics of all pregnancies in the database are presented. For analysis 2, characteristics are presented only for the index pregnancy (ie, the first pregnancy in the database), and we exclude HIV-positive women with no CD4+ T-cell count measurements and women whose estimated pregnancy end date is after the end of 2017.

Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus.

aIn analysis 1, pregnancies are only classified as involving HIV-positive women if there is evidence of HIV before the pregnancy outcome date; in analysis 2, pregnancy intervals are classified as HIV positive if there is any evidence of HIV (ie, evidence before or after the index pregnancy outcome date).

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