Table 2 Open in new tab Long-term change... | Oxford Academic

Table 2

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Long-term change in MMSE by treatment arm. Clinically significant change in MMSE score at key evaluations for patients without tumor progression

	Year
	0	1	2	3	5	7	8	10	12	15
Alive	203	192	178	166	132	113	102	85	68	44
Alive, baseline MMSE	187	178	165	153	121	103	94	78	62	39
Alive, prog-free, baseline MMSE	187	162	141	126	91	69	63	45	34	18
Abnormal baseline MMSE	47	35	26	22	12	7	7	4	3	3
n with MMSE	47	25	19	16	7	2	4	2	1	1
Decrease		1	1	1	0	0	0	0	1	0
Increase		10	9	6	1	1	2	1	0	0
Stable		14	9	9	6	1	2	1	0	1
Normal baseline MMSE	140	127	115	104	79	62	56	41	31	15
n with MMSE	140	97	87	69	42	20	20	12	3	1
Decrease		7	3	2	2	1	1	0	0	0
Stable		90	84	67	40	19	19	12	3	1

	Year
	0	1	2	3	5	7	8	10	12	15
Alive	203	192	178	166	132	113	102	85	68	44
Alive, baseline MMSE	187	178	165	153	121	103	94	78	62	39
Alive, prog-free, baseline MMSE	187	162	141	126	91	69	63	45	34	18
Abnormal baseline MMSE	47	35	26	22	12	7	7	4	3	3
n with MMSE	47	25	19	16	7	2	4	2	1	1
Decrease		1	1	1	0	0	0	0	1	0
Increase		10	9	6	1	1	2	1	0	0
Stable		14	9	9	6	1	2	1	0	1
Normal baseline MMSE	140	127	115	104	79	62	56	41	31	15
n with MMSE	140	97	87	69	42	20	20	12	3	1
Decrease		7	3	2	2	1	1	0	0	0
Stable		90	84	67	40	19	19	12	3	1

Table 2

Open in new tab

Long-term change in MMSE by treatment arm. Clinically significant change in MMSE score at key evaluations for patients without tumor progression

	Year
	0	1	2	3	5	7	8	10	12	15
Alive	203	192	178	166	132	113	102	85	68	44
Alive, baseline MMSE	187	178	165	153	121	103	94	78	62	39
Alive, prog-free, baseline MMSE	187	162	141	126	91	69	63	45	34	18
Abnormal baseline MMSE	47	35	26	22	12	7	7	4	3	3
n with MMSE	47	25	19	16	7	2	4	2	1	1
Decrease		1	1	1	0	0	0	0	1	0
Increase		10	9	6	1	1	2	1	0	0
Stable		14	9	9	6	1	2	1	0	1
Normal baseline MMSE	140	127	115	104	79	62	56	41	31	15
n with MMSE	140	97	87	69	42	20	20	12	3	1
Decrease		7	3	2	2	1	1	0	0	0
Stable		90	84	67	40	19	19	12	3	1

	Year
	0	1	2	3	5	7	8	10	12	15
Alive	203	192	178	166	132	113	102	85	68	44
Alive, baseline MMSE	187	178	165	153	121	103	94	78	62	39
Alive, prog-free, baseline MMSE	187	162	141	126	91	69	63	45	34	18
Abnormal baseline MMSE	47	35	26	22	12	7	7	4	3	3
n with MMSE	47	25	19	16	7	2	4	2	1	1
Decrease		1	1	1	0	0	0	0	1	0
Increase		10	9	6	1	1	2	1	0	0
Stable		14	9	9	6	1	2	1	0	1
Normal baseline MMSE	140	127	115	104	79	62	56	41	31	15
n with MMSE	140	97	87	69	42	20	20	12	3	1
Decrease		7	3	2	2	1	1	0	0	0
Stable		90	84	67	40	19	19	12	3	1